Detailed information NTG1127524

Bioinformatically predicted

Overview

• Name: comYD
• Type: Machinery gene
• Locus tag: FGL12_RS09805
• Genome accession: NZ_LR594041
• Coordinates: 2029011..2029439 (-)
• Length: 142 a.a.
• NCBI ID: WP_012130939.1
• Uniprot ID: A8AZH7
• Organism: Streptococcus gordonii strain NCTC9124
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2024011..2034439

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL12_RS11060	-	2024975..2025406 (-)	432	WP_231069241.1	CPBP family intramembrane glutamic endopeptidase	-
FGL12_RS09780 (NCTC9124_01971)	-	2025688..2026878 (-)	1191	WP_012130934.1	acetate kinase	-
FGL12_RS09785 (NCTC9124_01972)	comYH	2026928..2027881 (-)	954	WP_012130935.1	class I SAM-dependent methyltransferase	Machinery gene
FGL12_RS09790 (NCTC9124_01973)	comGG	2027912..2028343 (-)	432	WP_223341947.1	competence type IV pilus minor pilin ComGG	-
FGL12_RS09795 (NCTC9124_01974)	comGF/cglF	2028324..2028713 (-)	390	WP_241974402.1	competence type IV pilus minor pilin ComGF	Machinery gene
FGL12_RS09800 (NCTC9124_01975)	comGE/cglE	2028740..2029039 (-)	300	WP_138101351.1	competence type IV pilus minor pilin ComGE	Machinery gene
FGL12_RS09805 (NCTC9124_01976)	comYD	2029011..2029439 (-)	429	WP_012130939.1	competence type IV pilus minor pilin ComGD	Machinery gene
FGL12_RS09810 (NCTC9124_01977)	comYC	2029399..2029716 (-)	318	WP_012130940.1	competence type IV pilus major pilin ComGC	Machinery gene
FGL12_RS09815 (NCTC9124_01978)	comYB	2029713..2030747 (-)	1035	WP_012130941.1	competence type IV pilus assembly protein ComGB	Machinery gene
FGL12_RS09820 (NCTC9124_01979)	comYA	2030659..2031618 (-)	960	WP_012130942.1	competence type IV pilus ATPase ComGA	Machinery gene
FGL12_RS09825 (NCTC9124_01980)	-	2031720..2032088 (-)	369	WP_012130943.1	DUF1033 family protein	-

Sequence

Protein

• Length: 142 a.a.
• Molecular weight: 16043.65 Da
• Isoelectric Point: 10.1975

>NTDB_id=1127524 FGL12_RS09805 WP_012130939.1 2029011..2029439(-) (comYD) [Streptococcus gordonii strain NCTC9124]
MVRTIVRLRQLPIKAFTVLESLLVLMISSFILLALSSSVQATFEQIQAKIFFLEFEHFYQESQKLSVSSQRKLVLEISSQ
EISNGYARLPIPKGIQAPESTQIYFDKAGGNSSLSKVQFQTKEGLVTYQLYIGNGKFKKTTN

Nucleotide

• Length: 429 bp

>NTDB_id=1127524 FGL12_RS09805 WP_012130939.1 2029011..2029439(-) (comYD) [Streptococcus gordonii strain NCTC9124]
ATGGTAAGAACAATAGTGAGACTCAGGCAGTTGCCAATTAAGGCCTTTACGGTTTTGGAAAGCCTCTTGGTCTTGATGAT
TAGCAGTTTTATCTTGCTGGCTTTATCAAGCTCTGTTCAAGCTACATTTGAACAGATTCAGGCAAAGATCTTCTTTTTAG
AATTTGAGCATTTTTATCAGGAAAGTCAGAAGCTTAGCGTATCTTCTCAGAGAAAGCTGGTGCTAGAAATATCCAGTCAA
GAGATTTCAAATGGTTATGCTCGTCTTCCAATTCCTAAAGGAATCCAAGCACCTGAATCTACACAGATCTATTTTGATAA
GGCTGGTGGTAATTCTTCACTCAGTAAAGTTCAGTTTCAAACCAAGGAAGGACTGGTGACCTATCAACTCTATATTGGAA
ATGGCAAATTTAAGAAAACGACAAATTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A8AZH7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYD	Streptococcus gordonii str. Challis substr. CH1	100	100	1
comGD/cglD	Streptococcus pneumoniae TIGR4	59.055	89.437	0.528
comGD/cglD	Streptococcus mitis SK321	59.055	89.437	0.528
comGD/cglD	Streptococcus pneumoniae Rx1	59.055	89.437	0.528
comGD/cglD	Streptococcus pneumoniae D39	59.055	89.437	0.528
comGD/cglD	Streptococcus pneumoniae R6	59.055	89.437	0.528
comGD/cglD	Streptococcus mitis NCTC 12261	55.97	94.366	0.528
comYD	Streptococcus mutans UA140	50.388	90.845	0.458
comYD	Streptococcus mutans UA159	50.388	90.845	0.458
comGD	Lactococcus lactis subsp. cremoris KW2	36.879	99.296	0.366