Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   FGL12_RS09800 Genome accession   NZ_LR594041
Coordinates   2028740..2029039 (-) Length   99 a.a.
NCBI ID   WP_138101351.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC9124     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2023740..2034039
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL12_RS09770 (NCTC9124_01969) folP 2023932..2024897 (-) 966 WP_012130932.1 dihydropteroate synthase -
  FGL12_RS11060 - 2024975..2025406 (-) 432 WP_231069241.1 CPBP family intramembrane glutamic endopeptidase -
  FGL12_RS09780 (NCTC9124_01971) - 2025688..2026878 (-) 1191 WP_012130934.1 acetate kinase -
  FGL12_RS09785 (NCTC9124_01972) comYH 2026928..2027881 (-) 954 WP_012130935.1 class I SAM-dependent methyltransferase Machinery gene
  FGL12_RS09790 (NCTC9124_01973) comGG 2027912..2028343 (-) 432 WP_223341947.1 competence type IV pilus minor pilin ComGG -
  FGL12_RS09795 (NCTC9124_01974) comGF/cglF 2028324..2028713 (-) 390 WP_241974402.1 competence type IV pilus minor pilin ComGF Machinery gene
  FGL12_RS09800 (NCTC9124_01975) comGE/cglE 2028740..2029039 (-) 300 WP_138101351.1 competence type IV pilus minor pilin ComGE Machinery gene
  FGL12_RS09805 (NCTC9124_01976) comYD 2029011..2029439 (-) 429 WP_012130939.1 competence type IV pilus minor pilin ComGD Machinery gene
  FGL12_RS09810 (NCTC9124_01977) comYC 2029399..2029716 (-) 318 WP_012130940.1 competence type IV pilus major pilin ComGC Machinery gene
  FGL12_RS09815 (NCTC9124_01978) comYB 2029713..2030747 (-) 1035 WP_012130941.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGL12_RS09820 (NCTC9124_01979) comYA 2030659..2031618 (-) 960 WP_012130942.1 competence type IV pilus ATPase ComGA Machinery gene
  FGL12_RS09825 (NCTC9124_01980) - 2031720..2032088 (-) 369 WP_012130943.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 99 a.a.        Molecular weight: 11083.04 Da        Isoelectric Point: 10.0137

>NTDB_id=1127523 FGL12_RS09800 WP_138101351.1 2028740..2029039(-) (comGE/cglE) [Streptococcus gordonii strain NCTC9124]
MANLRKRQIKGTILLEALLALGVFAVIASLLLGQITQSRKEAAVILQKEEVLQVAQMALQTGQDHLSLNGIEIRIQRTKD
QIRVFHQGEELIDVEKKVN

Nucleotide


Download         Length: 300 bp        

>NTDB_id=1127523 FGL12_RS09800 WP_138101351.1 2028740..2029039(-) (comGE/cglE) [Streptococcus gordonii strain NCTC9124]
ATGGCAAATTTAAGAAAACGACAAATTAAAGGGACTATTTTACTGGAAGCCTTACTAGCTTTGGGAGTTTTTGCTGTAAT
TGCAAGTTTGCTACTAGGTCAAATCACGCAATCACGCAAAGAAGCAGCTGTCATTTTACAAAAAGAAGAGGTCCTGCAGG
TGGCCCAAATGGCCCTCCAAACAGGGCAGGACCATCTTTCCTTAAATGGCATTGAAATTCGGATTCAGAGAACAAAGGAT
CAGATTCGAGTATTCCATCAGGGGGAGGAATTGATTGATGTTGAAAAAAAGGTAAACTAG

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

53.763

93.939

0.505
  comGE/cglE Streptococcus pneumoniae D39

53.763

93.939

0.505
  comGE/cglE Streptococcus pneumoniae R6

53.763

93.939

0.505
  comGE/cglE Streptococcus pneumoniae TIGR4

53.763

93.939

0.505
  comGE/cglE Streptococcus mitis NCTC 12261

51.613

93.939

0.485
  comGE/cglE Streptococcus mitis SK321

51.613

93.939

0.485
  comYE Streptococcus mutans UA140

43.299

97.98

0.424
  comYE Streptococcus mutans UA159

43.299

97.98

0.424

Multiple sequence alignment