Detailed information NTG1127157

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: FGK99_RS00720
• Genome accession: NZ_LR594033
• Coordinates: 126151..126474 (+)
• Length: 107 a.a.
• NCBI ID: WP_012514782.1
• Uniprot ID: B4U056
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC4675
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 121151..131474

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGK99_RS00700 (NCTC4675_00141)	-	121416..123419 (+)	2004	WP_043024947.1	DUF1430 domain-containing protein	-
FGK99_RS00705 (NCTC4675_00142)	-	123421..124089 (+)	669	WP_043024949.1	ATP-binding cassette domain-containing protein	-
FGK99_RS00710 (NCTC4675_00143)	comGA/cglA	124245..125183 (+)	939	WP_021320259.1	competence type IV pilus ATPase ComGA	Machinery gene
FGK99_RS00715 (NCTC4675_00144)	comYB	125116..126150 (+)	1035	WP_229296759.1	competence type IV pilus assembly protein ComGB	Machinery gene
FGK99_RS00720 (NCTC4675_00145)	comGC/cglC	126151..126474 (+)	324	WP_012514782.1	competence type IV pilus major pilin ComGC	Machinery gene
FGK99_RS00725 (NCTC4675_00146)	comGD	126452..126877 (+)	426	WP_012514783.1	competence type IV pilus minor pilin ComGD	-
FGK99_RS00730 (NCTC4675_00147)	comGE	126882..127124 (+)	243	WP_012677236.1	competence type IV pilus minor pilin ComGE	-
FGK99_RS00735 (NCTC4675_00148)	comYF	127111..127545 (+)	435	WP_012677237.1	competence type IV pilus minor pilin ComGF	Machinery gene
FGK99_RS00740 (NCTC4675_00149)	comGG	127523..127885 (+)	363	WP_043024957.1	competence type IV pilus minor pilin ComGG	-
FGK99_RS00750 (NCTC4675_00152)	comYH	129379..130332 (+)	954	WP_043024962.1	class I SAM-dependent methyltransferase	Machinery gene

Sequence

Protein

• Length: 107 a.a.
• Molecular weight: 12149.19 Da
• Isoelectric Point: 8.4057

>NTDB_id=1127157 FGK99_RS00720 WP_012514782.1 126151..126474(+) (comGC/cglC) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKDKVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQE
DGSISDKQQKAYQDYYAKHKDEAKKLN

Nucleotide

• Length: 324 bp

>NTDB_id=1127157 FGK99_RS00720 WP_012514782.1 126151..126474(+) (comGC/cglC) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
ATGAAAATGAGATTATCAATCTTAAAAGATCAAGGTGTTCAGGCCTTCACTTTACTGGAAATGCTTCTGGTTTTGTTAAT
CATTAGTGTTTTGATGCTGTTATTTGTTCCAAATTTAAGTAAACAAAAGGATAAGGTGACAGACACAGGCAATGCTGCGG
TGGTAAAGCTGGTTGAAAATCAGGCAGAGCTTTATGAATTATCACATGGGGAAAAGCCAAGCCTGAAGCAGCTGCAAGAG
GATGGAAGTATCAGTGACAAGCAGCAAAAGGCTTATCAGGATTATTATGCAAAGCATAAAGATGAAGCTAAGAAGCTCAA
TTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (14-34)

3D structure

• AlphaFold DB: B4U056

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis SK321	59.813	100	0.598
comGC/cglC	Streptococcus pneumoniae Rx1	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae D39	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae R6	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae TIGR4	57.944	100	0.579
comYC	Streptococcus gordonii str. Challis substr. CH1	62.245	91.589	0.57
comGC/cglC	Streptococcus mitis NCTC 12261	61.616	92.523	0.57
comYC	Streptococcus mutans UA140	58.763	90.654	0.533
comYC	Streptococcus mutans UA159	58.763	90.654	0.533
comGC	Lactococcus lactis subsp. cremoris KW2	56.842	88.785	0.505
comYC	Streptococcus suis isolate S10	60	74.766	0.449
comGC	Staphylococcus aureus MW2	50	72.897	0.364
comGC	Staphylococcus aureus N315	50	72.897	0.364