Detailed information NTG1119862

Bioinformatically predicted

Overview

• Name: comX
• Type: Regulator
• Locus tag: EL076_RS00910
• Genome accession: NZ_LR134275
• Coordinates: 145924..146421 (+)
• Length: 165 a.a.
• NCBI ID: WP_003095137.1
• Uniprot ID: A0A3E4XFR1
• Organism: Streptococcus vestibularis strain NCTC12167
• Function: activation of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 140924..151421

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL076_RS00895	-	143937..144366 (-)	430	Protein_117	helix-turn-helix domain-containing protein	-
EL076_RS00900	-	144713..144888 (+)	176	Protein_118	transposase	-
EL076_RS09905 (NCTC12167_00174)	-	145093..145374 (+)	282	WP_064519106.1	helix-turn-helix domain-containing protein	-
EL076_RS09910 (NCTC12167_00175)	-	145453..145596 (+)	144	WP_225901374.1	hypothetical protein	-
EL076_RS00910 (NCTC12167_00176)	comX	145924..146421 (+)	498	WP_003095137.1	sigma factor	Regulator
EL076_RS00915 (NCTC12167_00177)	-	146524..147366 (-)	843	WP_126428913.1	mechanosensitive ion channel family protein	-
EL076_RS00920 (NCTC12167_00178)	tig	147509..148792 (+)	1284	WP_003095183.1	trigger factor	-
EL076_RS00925 (NCTC12167_00179)	rpoE	148950..149525 (+)	576	WP_003098181.1	DNA-directed RNA polymerase subunit delta	-
EL076_RS00930 (NCTC12167_00180)	-	149777..151381 (+)	1605	WP_126428914.1	CTP synthase	-

Sequence

Protein

• Length: 165 a.a.
• Molecular weight: 20077.92 Da
• Isoelectric Point: 5.0125

>NTDB_id=1119862 EL076_RS00910 WP_003095137.1 145924..146421(+) (comX) [Streptococcus vestibularis strain NCTC12167]
MEQEVFVHAYETVRPIVLKAFRQYFIQLWDQADMEQEAMMTLYQLLKKFPDLEKDDDKLRRYFKTKFRNRLNDEVRRQES
VKRQANRQCYVEISDIAFCIPNKELDTVDRLAYDEQLNAFREQLSSEDSLKLDRLLAGECFRGRKKMIRELRVWMVDFDP
CNEED

Nucleotide

• Length: 498 bp

>NTDB_id=1119862 EL076_RS00910 WP_003095137.1 145924..146421(+) (comX) [Streptococcus vestibularis strain NCTC12167]
ATGGAACAAGAAGTTTTTGTTCACGCATATGAAACTGTAAGGCCGATTGTACTTAAGGCTTTTAGGCAATACTTTATTCA
GCTTTGGGATCAAGCTGACATGGAGCAAGAGGCGATGATGACTTTGTATCAGCTTTTAAAAAAGTTTCCTGATTTAGAGA
AAGATGATGATAAGTTACGTCGTTACTTTAAAACTAAGTTTAGGAATCGACTTAATGATGAAGTGAGGCGGCAGGAGTCA
GTAAAACGTCAAGCTAATAGACAGTGCTATGTTGAAATCTCAGATATTGCTTTTTGTATTCCCAATAAGGAGCTAGATAC
GGTTGATAGACTTGCTTATGATGAGCAGCTTAATGCTTTTCGTGAGCAGTTATCATCGGAAGATTCTCTTAAGTTGGATC
GATTGTTGGCTGGTGAATGCTTTAGGGGAAGGAAAAAGATGATACGAGAGTTAAGAGTTTGGATGGTTGACTTTGATCCA
TGTAATGAAGAAGACTGA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A3E4XFR1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX	Streptococcus thermophilus LMD-9	96.97	100	0.97
comX	Streptococcus thermophilus LMG 18311	96.97	100	0.97
comX/sigX	Streptococcus salivarius strain HSISS4	89.697	100	0.897
comX	Streptococcus salivarius SK126	89.091	100	0.891
comX	Streptococcus sobrinus strain NIDR 6715-7	43.21	98.182	0.424
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	42.949	94.545	0.406
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	43.226	93.939	0.406
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	43.226	93.939	0.406
comX/sigX	Streptococcus mutans UA159	41.026	94.545	0.388
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	42	90.909	0.382
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	42	90.909	0.382
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	42	90.909	0.382
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	42	90.909	0.382
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	41.333	90.909	0.376
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	41.333	90.909	0.376
comX/sigX	Streptococcus suis D9	39.869	92.727	0.37
comX/sigX	Streptococcus suis isolate S10	39.869	92.727	0.37
comX/sigX	Streptococcus suis P1/7	39.869	92.727	0.37