Detailed information NTG1111773

Bioinformatically predicted

Overview

• Name: comX
• Type: Regulator
• Locus tag: HMPREF9425_RS08395
• Genome accession: NZ_GL831112
• Coordinates: 1741579..1742076 (-)
• Length: 165 a.a.
• NCBI ID: WP_003095137.1
• Uniprot ID: A0A3E4XFR1
• Organism: Streptococcus vestibularis ATCC 49124
• Function: activation of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1736579..1747076

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF9425_RS08375 (HMPREF9425_1754)	-	1736619..1738223 (-)	1605	WP_002885608.1	CTP synthase	-
HMPREF9425_RS08380 (HMPREF9425_1755)	rpoE	1738475..1739050 (-)	576	WP_003098181.1	DNA-directed RNA polymerase subunit delta	-
HMPREF9425_RS08385 (HMPREF9425_1756)	tig	1739208..1740491 (-)	1284	WP_003095183.1	trigger factor	-
HMPREF9425_RS08390 (HMPREF9425_1757)	-	1740634..1741476 (+)	843	WP_003098186.1	mechanosensitive ion channel family protein	-
HMPREF9425_RS08395 (HMPREF9425_1758)	comX	1741579..1742076 (-)	498	WP_003095137.1	sigma factor	Regulator
HMPREF9425_RS08400 (HMPREF9425_1759)	-	1742404..1742547 (-)	144	WP_225901374.1	hypothetical protein	-
HMPREF9425_RS10110 (HMPREF9425_1760)	-	1742626..1742847 (-)	222	WP_003098189.1	transposase	-
HMPREF9425_RS09600	-	1743113..1743327 (-)	215	Protein_1717	transposase	-
HMPREF9425_RS09605	-	1743631..1743958 (+)	328	Protein_1718	helix-turn-helix domain-containing protein	-

Sequence

Protein

• Length: 165 a.a.
• Molecular weight: 20077.92 Da
• Isoelectric Point: 5.0125

>NTDB_id=1111773 HMPREF9425_RS08395 WP_003095137.1 1741579..1742076(-) (comX) [Streptococcus vestibularis ATCC 49124]
MEQEVFVHAYETVRPIVLKAFRQYFIQLWDQADMEQEAMMTLYQLLKKFPDLEKDDDKLRRYFKTKFRNRLNDEVRRQES
VKRQANRQCYVEISDIAFCIPNKELDTVDRLAYDEQLNAFREQLSSEDSLKLDRLLAGECFRGRKKMIRELRVWMVDFDP
CNEED

Nucleotide

• Length: 498 bp

>NTDB_id=1111773 HMPREF9425_RS08395 WP_003095137.1 1741579..1742076(-) (comX) [Streptococcus vestibularis ATCC 49124]
ATGGAACAAGAAGTTTTTGTTCACGCATATGAAACTGTAAGGCCGATTGTACTTAAGGCTTTTAGGCAATACTTTATTCA
GCTTTGGGATCAAGCTGACATGGAGCAAGAGGCGATGATGACTTTGTATCAGCTTTTAAAAAAGTTTCCTGATTTAGAGA
AAGATGATGATAAGTTACGTCGTTACTTTAAAACTAAGTTTAGGAATCGACTTAATGATGAAGTGAGGCGGCAGGAGTCA
GTAAAACGTCAAGCTAATAGACAGTGCTATGTTGAAATCTCAGATATTGCTTTTTGTATTCCCAATAAGGAGCTAGATAC
GGTTGATAGACTTGCTTATGATGAGCAGCTTAATGCTTTTCGTGAGCAGTTATCATCGGAAGATTCTCTTAAGTTGGATC
GATTGTTGGCTGGTGAATGCTTTAGGGGAAGGAAAAAGATGATACGAGAGTTAAGAGTTTGGATGGTTGACTTTGATCCA
TGTAATGAAGAAGACTGA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A3E4XFR1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX	Streptococcus thermophilus LMD-9	96.97	100	0.97
comX	Streptococcus thermophilus LMG 18311	96.97	100	0.97
comX/sigX	Streptococcus salivarius strain HSISS4	89.697	100	0.897
comX	Streptococcus salivarius SK126	89.091	100	0.891
comX	Streptococcus sobrinus strain NIDR 6715-7	43.21	98.182	0.424
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	42.949	94.545	0.406
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	43.226	93.939	0.406
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	43.226	93.939	0.406
comX/sigX	Streptococcus mutans UA159	41.026	94.545	0.388
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	42	90.909	0.382
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	42	90.909	0.382
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	42	90.909	0.382
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	42	90.909	0.382
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	41.333	90.909	0.376
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	41.333	90.909	0.376
comX/sigX	Streptococcus suis D9	39.869	92.727	0.37
comX/sigX	Streptococcus suis isolate S10	39.869	92.727	0.37
comX/sigX	Streptococcus suis P1/7	39.869	92.727	0.37