Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   AAA985_RS10440 Genome accession   NZ_AP028603
Coordinates   1979853..1980179 (-) Length   108 a.a.
NCBI ID   WP_050260822.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Pne2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1974853..1985179
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAA985_RS10395 (TKY181970_20270) rnpA 1974870..1975241 (-) 372 WP_000739244.1 ribonuclease P protein component -
  AAA985_RS10400 - 1975258..1975389 (-) 132 WP_000768904.1 hypothetical protein -
  AAA985_RS10405 (TKY181970_20280) - 1975390..1976580 (-) 1191 WP_000167752.1 acetate kinase -
  AAA985_RS10410 (TKY181970_20290) comYH 1976631..1977584 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  AAA985_RS10415 - 1977645..1978239 (-) 595 Protein_2027 methyltransferase domain-containing protein -
  AAA985_RS10420 (TKY181970_20320) comGG/cglG 1978376..1978789 (-) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  AAA985_RS10425 (TKY181970_20330) comGF/cglF 1978767..1979228 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  AAA985_RS10430 (TKY181970_20340) comGE/cglE 1979191..1979493 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  AAA985_RS10435 (TKY181970_20350) comGD/cglD 1979456..1979860 (-) 405 WP_000588023.1 competence type IV pilus minor pilin ComGD Machinery gene
  AAA985_RS10440 (TKY181970_20360) comGC/cglC 1979853..1980179 (-) 327 WP_050260822.1 comG operon protein ComGC Machinery gene
  AAA985_RS10445 (TKY181970_20370) comGB/cglB 1980181..1981197 (-) 1017 WP_073177425.1 competence type IV pilus assembly protein ComGB Machinery gene
  AAA985_RS10450 (TKY181970_20380) comGA/cglA/cilD 1981145..1982086 (-) 942 WP_000249559.1 competence type IV pilus ATPase ComGA Machinery gene
  AAA985_RS10455 (TKY181970_20390) - 1982162..1982527 (-) 366 WP_000286415.1 DUF1033 family protein -
  AAA985_RS10460 (TKY181970_20400) - 1982794..1984049 (+) 1256 WP_088804233.1 ISL3 family transposase -
  AAA985_RS10465 (TKY181970_20410) - 1984098..1985156 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12316.49 Da        Isoelectric Point: 10.0300

>NTDB_id=106001 AAA985_RS10440 WP_050260822.1 1979853..1980179(-) (comGC/cglC) [Streptococcus pneumoniae strain Pne2]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDARLSKLKD
DGRITEEQAKAYKEYHDKNGEANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=106001 AAA985_RS10440 WP_050260822.1 1979853..1980179(-) (comGC/cglC) [Streptococcus pneumoniae strain Pne2]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGACTAAGCAAGTTAAAAGAC
GATGGGCGAATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGAAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

95.37

100

0.954
  comGC/cglC Streptococcus pneumoniae D39

95.37

100

0.954
  comGC/cglC Streptococcus pneumoniae R6

95.37

100

0.954
  comGC/cglC Streptococcus pneumoniae TIGR4

94.444

100

0.944
  comGC/cglC Streptococcus mitis SK321

91.667

100

0.917
  comGC/cglC Streptococcus mitis NCTC 12261

93.878

90.741

0.852
  comYC Streptococcus gordonii str. Challis substr. CH1

67.961

95.37

0.648
  comYC Streptococcus mutans UA140

62.745

94.444

0.593
  comYC Streptococcus mutans UA159

62.745

94.444

0.593
  comGC Lactococcus lactis subsp. cremoris KW2

54.902

94.444

0.519
  comYC Streptococcus suis isolate S10

67.901

75

0.509
  comGC Staphylococcus aureus MW2

45.098

94.444

0.426
  comGC Staphylococcus aureus N315

45.098

94.444

0.426

Multiple sequence alignment