Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   AAA985_RS10410 Genome accession   NZ_AP028603
Coordinates   1976631..1977584 (-) Length   317 a.a.
NCBI ID   WP_000345126.1    Uniprot ID   A0A0F7YBB9
Organism   Streptococcus pneumoniae strain Pne2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1971631..1982584
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAA985_RS10380 (TKY181970_20240) - 1972392..1973015 (-) 624 WP_000932657.1 hypothetical protein -
  AAA985_RS10385 (TKY181970_20250) jag 1973066..1974052 (-) 987 WP_000260027.1 RNA-binding cell elongation regulator Jag/EloR -
  AAA985_RS10390 (TKY181970_20260) - 1974071..1974895 (-) 825 WP_001832473.1 membrane protein insertase YidC -
  AAA985_RS10395 (TKY181970_20270) rnpA 1974870..1975241 (-) 372 WP_000739244.1 ribonuclease P protein component -
  AAA985_RS10400 - 1975258..1975389 (-) 132 WP_000768904.1 hypothetical protein -
  AAA985_RS10405 (TKY181970_20280) - 1975390..1976580 (-) 1191 WP_000167752.1 acetate kinase -
  AAA985_RS10410 (TKY181970_20290) comYH 1976631..1977584 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  AAA985_RS10415 - 1977645..1978239 (-) 595 Protein_2027 methyltransferase domain-containing protein -
  AAA985_RS10420 (TKY181970_20320) comGG/cglG 1978376..1978789 (-) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  AAA985_RS10425 (TKY181970_20330) comGF/cglF 1978767..1979228 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  AAA985_RS10430 (TKY181970_20340) comGE/cglE 1979191..1979493 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  AAA985_RS10435 (TKY181970_20350) comGD/cglD 1979456..1979860 (-) 405 WP_000588023.1 competence type IV pilus minor pilin ComGD Machinery gene
  AAA985_RS10440 (TKY181970_20360) comGC/cglC 1979853..1980179 (-) 327 WP_050260822.1 comG operon protein ComGC Machinery gene
  AAA985_RS10445 (TKY181970_20370) comGB/cglB 1980181..1981197 (-) 1017 WP_073177425.1 competence type IV pilus assembly protein ComGB Machinery gene
  AAA985_RS10450 (TKY181970_20380) comGA/cglA/cilD 1981145..1982086 (-) 942 WP_000249559.1 competence type IV pilus ATPase ComGA Machinery gene
  AAA985_RS10455 (TKY181970_20390) - 1982162..1982527 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35714.87 Da        Isoelectric Point: 4.2434

>NTDB_id=105996 AAA985_RS10410 WP_000345126.1 1976631..1977584(-) (comYH) [Streptococcus pneumoniae strain Pne2]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=105996 AAA985_RS10410 WP_000345126.1 1976631..1977584(-) (comYH) [Streptococcus pneumoniae strain Pne2]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTACTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAACCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBB9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536

Multiple sequence alignment