Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   BJR96_RS01145 Genome accession   NZ_LT545678
Coordinates   199273..200244 (+) Length   323 a.a.
NCBI ID   WP_000250798.1    Uniprot ID   -
Organism   Streptococcus agalactiae isolate SA111     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 194273..205244
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BJR96_RS01135 (SA111_00213) - 197172..197537 (+) 366 WP_000285374.1 DUF1033 family protein -
  BJR96_RS01140 (SA111_00214) - 197767..199227 (+) 1461 WP_000468685.1 IS1182-like element IS1563 family transposase -
  BJR96_RS01145 (SA111_00215) comGA 199273..200244 (+) 972 WP_000250798.1 competence type IV pilus ATPase ComGA Machinery gene
  BJR96_RS01150 (SA111_00216) comGB 200138..201181 (+) 1044 WP_261368811.1 competence type IV pilus assembly protein ComGB Machinery gene
  BJR96_RS01155 (SA111_00217) comGC/cglC 201178..201507 (+) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  BJR96_RS01160 (SA111_00218) comGD 201482..201895 (+) 414 WP_000244259.1 competence type IV pilus minor pilin ComGD Machinery gene
  BJR96_RS01165 (SA111_00219) comGE 201867..202166 (+) 300 WP_001872488.1 competence type IV pilus minor pilin ComGE Machinery gene
  BJR96_RS01170 (SA111_00220) comGF 202120..202581 (+) 462 WP_001874060.1 competence type IV pilus minor pilin ComGF Machinery gene
  BJR96_RS01175 (SA111_00221) comGG 202559..202930 (+) 372 WP_000601101.1 competence type IV pilus minor pilin ComGG Machinery gene
  BJR96_RS01180 (SA111_00222) comGH 203045..204019 (+) 975 WP_001008569.1 class I SAM-dependent methyltransferase Machinery gene
  BJR96_RS01185 (SA111_00223) - 204051..205244 (+) 1194 WP_000047534.1 acetate kinase -

Sequence

Protein


Download         Length: 323 a.a.        Molecular weight: 36768.25 Da        Isoelectric Point: 6.9167

>NTDB_id=1027449 BJR96_RS01145 WP_000250798.1 199273..200244(+) (comGA) [Streptococcus agalactiae isolate SA111]
MVQSLAKHVIHQAVEVNAQDIYIIPKGDCYELYMRIDDERRFIDVFEFNRMASLISHFKFVAGMNVGEKRRSQLGSCDYE
LSEGRLVSLRLSSVGDYRGQESLVIRILYSGHQDLKYWFDNIKQMKEVLGARGLYLFSGPVGSGKTTLMYQLASEVFKNK
QIITIEDPVEIKNDKMLQLQLNEDIGMTYDALIKLSLRHRPDILIIGEIRDQATARAVIRASLTGVMVFSTIHAKSIPGV
YDRLIELGVNYQELENSLKLIAYQRLIGGGSLIDFETGNFKKHSSDKWNRQVDILAEEGHISKKQAQVEKIIPQETTESS
PTF

Nucleotide


Download         Length: 972 bp        

>NTDB_id=1027449 BJR96_RS01145 WP_000250798.1 199273..200244(+) (comGA) [Streptococcus agalactiae isolate SA111]
ATGGTTCAATCATTAGCAAAGCACGTCATCCATCAGGCAGTAGAAGTAAATGCTCAAGATATTTATATCATTCCCAAAGG
TGATTGTTATGAACTCTATATGCGTATTGATGATGAAAGGCGGTTTATTGATGTTTTTGAGTTTAATAGGATGGCTAGTC
TTATTAGTCACTTTAAATTTGTGGCAGGCATGAACGTTGGAGAAAAAAGACGAAGTCAATTAGGTTCTTGTGACTATGAA
CTGTCAGAGGGAAGACTGGTTTCATTACGACTATCAAGTGTGGGAGATTATCGTGGTCAAGAATCTTTAGTTATTCGTAT
TTTGTATTCAGGTCATCAGGACTTAAAATATTGGTTTGATAATATAAAGCAAATGAAGGAAGTACTGGGTGCAAGAGGGC
TATATCTTTTTTCCGGCCCTGTGGGGAGTGGTAAAACAACTCTCATGTATCAATTAGCTTCAGAAGTATTTAAAAATAAG
CAAATTATCACGATTGAAGATCCGGTAGAAATCAAGAATGACAAGATGTTACAACTCCAATTGAATGAGGATATTGGAAT
GACTTATGATGCTTTAATCAAACTGTCTTTACGGCATCGTCCAGATATTTTAATTATCGGAGAGATTAGAGATCAAGCGA
CGGCCCGTGCTGTTATTCGTGCAAGTTTAACGGGAGTGATGGTTTTTTCTACTATTCATGCTAAAAGTATTCCCGGAGTC
TATGATAGGCTTATAGAATTAGGGGTTAACTATCAAGAGTTAGAAAATAGTCTAAAATTAATAGCATATCAACGTTTAAT
TGGAGGAGGAAGCCTAATTGACTTTGAGACAGGTAATTTTAAAAAACACTCATCAGACAAGTGGAATAGACAAGTGGATA
TCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAAACAACGGAAAGTAGT
CCAACTTTTTAA

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Streptococcus mutans UA159

68.81

96.285

0.663
  comGA Streptococcus mutans UA140

68.81

96.285

0.663
  comGA Streptococcus gordonii str. Challis substr. CH1

63.636

98.762

0.628
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.701

96.285

0.604
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.736

96.285

0.594
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.736

96.285

0.594
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.736

96.285

0.594
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.736

96.285

0.594
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.935

95.975

0.594
  comGA Lactococcus lactis subsp. cremoris KW2

50.621

99.69

0.505