Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   BJR96_RS01150 Genome accession   NZ_LT545678
Coordinates   200138..201181 (+) Length   347 a.a.
NCBI ID   WP_261368811.1    Uniprot ID   -
Organism   Streptococcus agalactiae isolate SA111     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 195138..206181
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BJR96_RS01135 (SA111_00213) - 197172..197537 (+) 366 WP_000285374.1 DUF1033 family protein -
  BJR96_RS01140 (SA111_00214) - 197767..199227 (+) 1461 WP_000468685.1 IS1182-like element IS1563 family transposase -
  BJR96_RS01145 (SA111_00215) comGA 199273..200244 (+) 972 WP_000250798.1 competence type IV pilus ATPase ComGA Machinery gene
  BJR96_RS01150 (SA111_00216) comGB 200138..201181 (+) 1044 WP_261368811.1 competence type IV pilus assembly protein ComGB Machinery gene
  BJR96_RS01155 (SA111_00217) comGC/cglC 201178..201507 (+) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  BJR96_RS01160 (SA111_00218) comGD 201482..201895 (+) 414 WP_000244259.1 competence type IV pilus minor pilin ComGD Machinery gene
  BJR96_RS01165 (SA111_00219) comGE 201867..202166 (+) 300 WP_001872488.1 competence type IV pilus minor pilin ComGE Machinery gene
  BJR96_RS01170 (SA111_00220) comGF 202120..202581 (+) 462 WP_001874060.1 competence type IV pilus minor pilin ComGF Machinery gene
  BJR96_RS01175 (SA111_00221) comGG 202559..202930 (+) 372 WP_000601101.1 competence type IV pilus minor pilin ComGG Machinery gene
  BJR96_RS01180 (SA111_00222) comGH 203045..204019 (+) 975 WP_001008569.1 class I SAM-dependent methyltransferase Machinery gene
  BJR96_RS01185 (SA111_00223) - 204051..205244 (+) 1194 WP_000047534.1 acetate kinase -
  BJR96_RS01190 - 205372..205564 (+) 193 Protein_180 helix-turn-helix transcriptional regulator -
  BJR96_RS01195 - 205543..205830 (+) 288 Protein_181 hypothetical protein -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 40074.87 Da        Isoelectric Point: 9.9642

>NTDB_id=1027450 BJR96_RS01150 WP_261368811.1 200138..201181(+) (comGB) [Streptococcus agalactiae isolate SA111]
MDKWISWLKKDISVRNRHKSKKLSLKKQRKVVQLFNNLFASGFSLTDMVTFLKRSKLLSDCYTDRMNKALLEGKDLSKML
GELGFSDTVITQVALADLHGNISRSLLKIEFYLANLLLVRKKVIEVATYPLILLSFLVLIMIGLRHYLMPQLGENNFATR
LITNVPNIFLLLLAVVLIFSLIFYIIQKRLSRIKVACFLTTIPLVGSYVKLYLTAYYAREWGNLLSQGVELDQIVKVMQN
QKSKLFREIGYDMEEGFLSGKAFHQKVLDYPFFLTELSLMIEYGQVKAKLGTELDIYADEKWEDFFTKLARATQLIQPVI
FIFVALIIVMIYAAMLLPMYQNMEILS

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=1027450 BJR96_RS01150 WP_261368811.1 200138..201181(+) (comGB) [Streptococcus agalactiae isolate SA111]
ATAGACAAGTGGATATCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAA
ACAACGGAAAGTAGTCCAACTTTTTAATAATCTTTTTGCTAGTGGTTTTTCTTTAACTGATATGGTCACCTTCTTAAAGA
GGAGTAAGTTATTGTCTGATTGTTATACAGATAGGATGAATAAGGCATTATTAGAGGGAAAAGATTTATCAAAAATGTTA
GGAGAGTTAGGTTTTTCTGACACTGTTATCACACAGGTTGCATTAGCTGATTTGCATGGTAACATTTCAAGGAGCCTACT
AAAGATTGAGTTTTATTTAGCTAATCTTTTGTTAGTTAGAAAAAAAGTAATAGAAGTAGCTACTTACCCATTGATATTAT
TGTCTTTTCTGGTGCTAATTATGATTGGCCTTAGGCATTATTTAATGCCCCAATTAGGAGAAAATAATTTTGCAACTAGA
CTGATTACAAATGTGCCGAATATTTTCTTATTACTTTTAGCAGTTGTACTTATTTTTAGTTTAATATTTTATATTATTCA
AAAGCGATTGTCGCGCATTAAAGTAGCTTGTTTTTTAACAACAATTCCCTTAGTTGGATCATATGTTAAGCTTTATTTAA
CTGCTTACTATGCCCGTGAGTGGGGAAATTTATTAAGTCAAGGTGTTGAATTGGACCAAATTGTTAAAGTAATGCAAAAT
CAGAAATCCAAACTTTTTAGGGAAATAGGATATGACATGGAAGAAGGTTTTCTATCAGGTAAAGCATTTCACCAAAAAGT
ATTAGACTATCCGTTTTTCTTAACTGAGCTTAGTTTAATGATTGAATATGGTCAAGTTAAGGCGAAATTAGGAACAGAGT
TAGATATATATGCTGATGAGAAGTGGGAGGATTTTTTTACAAAATTAGCTAGAGCGACCCAGTTAATCCAACCTGTTATT
TTTATTTTTGTAGCTCTTATCATTGTTATGATTTATGCAGCAATGCTGTTACCAATGTATCAAAATATGGAGATATTATC
ATGA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Streptococcus mutans UA140

61.877

98.271

0.608
  comGB Streptococcus mutans UA159

61.584

98.271

0.605
  comGB Streptococcus gordonii str. Challis substr. CH1

56.012

98.271

0.55
  comGB/cglB Streptococcus mitis NCTC 12261

54.925

96.542

0.53
  comGB/cglB Streptococcus mitis SK321

54.328

96.542

0.524
  comGB/cglB Streptococcus pneumoniae Rx1

53.433

96.542

0.516
  comGB/cglB Streptococcus pneumoniae D39

53.433

96.542

0.516
  comGB/cglB Streptococcus pneumoniae R6

53.433

96.542

0.516
  comGB/cglB Streptococcus pneumoniae TIGR4

53.433

96.542

0.516
  comGB Lactococcus lactis subsp. cremoris KW2

50.148

97.118

0.487

Multiple sequence alignment