Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   ABKJ27_RS08470 Genome accession   NZ_CP157578
Coordinates   1741794..1742735 (-) Length   313 a.a.
NCBI ID   WP_410011681.1    Uniprot ID   -
Organism   Streptococcus sp. KHUD_011     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1736794..1747735
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKJ27_RS08430 (ABKJ27_08440) comYH 1737394..1738347 (-) 954 WP_410011679.1 class I SAM-dependent methyltransferase Machinery gene
  ABKJ27_RS08435 (ABKJ27_08445) - 1738408..1738995 (-) 588 WP_261052044.1 class I SAM-dependent methyltransferase -
  ABKJ27_RS08440 (ABKJ27_08450) comGG/cglG 1739028..1739441 (-) 414 WP_223340416.1 competence type IV pilus minor pilin ComGG Machinery gene
  ABKJ27_RS08445 (ABKJ27_08455) comGF/cglF 1739419..1739880 (-) 462 WP_020903618.1 competence type IV pilus minor pilin ComGF Machinery gene
  ABKJ27_RS08450 (ABKJ27_08460) comGE/cglE 1739843..1740145 (-) 303 WP_153197443.1 competence type IV pilus minor pilin ComGE Machinery gene
  ABKJ27_RS08455 (ABKJ27_08465) comGD/cglD 1740108..1740542 (-) 435 WP_410011680.1 competence type IV pilus minor pilin ComGD Machinery gene
  ABKJ27_RS08460 (ABKJ27_08470) comGC/cglC 1740505..1740828 (-) 324 WP_020903620.1 competence type IV pilus major pilin ComGC Machinery gene
  ABKJ27_RS08465 (ABKJ27_08475) comGB/cglB 1740830..1741846 (-) 1017 WP_410012147.1 competence type IV pilus assembly protein ComGB Machinery gene
  ABKJ27_RS08470 (ABKJ27_08480) comGA/cglA/cilD 1741794..1742735 (-) 942 WP_410011681.1 competence type IV pilus ATPase ComGA Machinery gene
  ABKJ27_RS08475 (ABKJ27_08485) - 1742812..1743177 (-) 366 WP_000286405.1 DUF1033 family protein -
  ABKJ27_RS08480 (ABKJ27_08490) - 1743422..1744480 (-) 1059 WP_004257473.1 zinc-dependent alcohol dehydrogenase family protein -
  ABKJ27_RS08485 (ABKJ27_08495) nagA 1744643..1745794 (-) 1152 WP_410011682.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35472.52 Da        Isoelectric Point: 6.6622

>NTDB_id=1007494 ABKJ27_RS08470 WP_410011681.1 1741794..1742735(-) (comGA/cglA/cilD) [Streptococcus sp. KHUD_011]
MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDKRCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKMASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELAKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFANKDYQAHQPTSWNKQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1007494 ABKJ27_RS08470 WP_410011681.1 1741794..1742735(-) (comGA/cglA/cilD) [Streptococcus sp. KHUD_011]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCGGCTCGGAAAAAAGGGGCACAAGACATTTATTTTGTCCCTAAGTT
AGACGCCTATGAGCTTCATATGAGGGTCGGAGACAAGCGCTGTAAAATCGGTTCTTATGATTTCGAAAAATTTGCGGCCG
TCATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTTGGAGAAAAGCGACGTAGTCAACTTGGTTCCTGTGATTATGCC
TATGACCAGAAGATGGCGTCCCTACGTCTATCTACCGTAGGCGATTATCGAGGGCATGAGAGTTTGGTGATTCGCTTGTT
GCATGATGAGGAGCAGGACTTGCATTTTTGGTTTCAGGACATTGAAGAATTGGGTAAGCAGTATAGGCAACGTGGTCTTT
ATCTTTTTGCTGGACCAGTCGGCAGTGGCAAGACAACCTTGATGCATGAATTGGCCAAGTCTCTCTTTAAAGGACAGCAG
GTCATGTCCATCGAAGATCCTGTTGAAATCAAGCAGGACGACATGCTCCAATTGCAGTTGAATGAGGCAATCGGGTTAAC
CTATGAAAATCTCATCAAACTTTCCTTACGGCATCGTCCTGATCTATTGATTATCGGAGAAATTCGGGACAGCGAGACGG
CGCGTGCGGTAGTCAGAGCCAGTTTGACAGGGGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATTCGAGGTGTTTAT
GAGCGACTGCTGGAGTTGGGTGTGAGTGAGGAAGAGTTGGCAGTCGTTCTACAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGATTTTGCAAACAAAGACTATCAAGCACACCAGCCAACTAGCTGGAATAAGCAGATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAAACAGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

97.764

100

0.978
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

96.166

100

0.962
  comGA/cglA/cilD Streptococcus pneumoniae D39

96.166

100

0.962
  comGA/cglA/cilD Streptococcus pneumoniae R6

96.166

100

0.962
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

96.166

100

0.962
  comYA Streptococcus gordonii str. Challis substr. CH1

78.387

99.042

0.776
  comYA Streptococcus mutans UA159

65.595

99.361

0.652
  comYA Streptococcus mutans UA140

65.595

99.361

0.652
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.581

99.042

0.62
  comGA Lactococcus lactis subsp. cremoris KW2

55.128

99.681

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

42.279

86.901

0.367

Multiple sequence alignment