Detailed information NTG1007228

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: ABLU29_RS04045
• Genome accession: NZ_CP157498
• Coordinates: 713428..713811 (+)
• Length: 127 a.a.
• NCBI ID: WP_010906318.1
• Uniprot ID: A0A3N6KXZ7
• Organism: Lactococcus lactis strain 2B-5
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 708428..718811

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABLU29_RS04035 (ABLU29_04025)	comGA	711509..712447 (+)	939	WP_058212859.1	competence type IV pilus ATPase ComGA	Machinery gene
ABLU29_RS04040 (ABLU29_04030)	comGB	712341..713414 (+)	1074	WP_406835453.1	competence type IV pilus assembly protein ComGB	Machinery gene
ABLU29_RS04045 (ABLU29_04035)	comGC	713428..713811 (+)	384	WP_010906318.1	competence type IV pilus major pilin ComGC	Machinery gene
ABLU29_RS04050 (ABLU29_04040)	comGD	713786..714202 (+)	417	WP_021216554.1	competence type IV pilus minor pilin ComGD	Machinery gene
ABLU29_RS04055 (ABLU29_04045)	comGE	714174..714470 (+)	297	WP_010906316.1	competence type IV pilus minor pilin ComGE	Machinery gene
ABLU29_RS04060 (ABLU29_04050)	comGF	714433..714879 (+)	447	WP_029344525.1	competence type IV pilus minor pilin ComGF	Machinery gene
ABLU29_RS04065 (ABLU29_04055)	comGG	714927..715202 (+)	276	WP_257012268.1	hypothetical protein	Machinery gene
ABLU29_RS04070 (ABLU29_04060)	-	715283..715720 (+)	438	WP_058213216.1	zinc-dependent MarR family transcriptional regulator	-
ABLU29_RS04075 (ABLU29_04065)	-	715717..716559 (+)	843	WP_015427160.1	metal ABC transporter substrate-binding protein	-
ABLU29_RS04080 (ABLU29_04070)	-	716736..717473 (+)	738	WP_012898617.1	metal ABC transporter ATP-binding protein	-
ABLU29_RS04085 (ABLU29_04075)	-	717466..718275 (+)	810	WP_014570791.1	metal ABC transporter permease	-

Sequence

Protein

• Length: 127 a.a.
• Molecular weight: 14797.39 Da
• Isoelectric Point: 8.4538

>NTDB_id=1007228 ABLU29_RS04045 WP_010906318.1 713428..713811(+) (comGC) [Lactococcus lactis strain 2B-5]
MERTKKFILKKIQKIFLFVKICEKKCRQKELKAFTLIEMLIVLAIISILILLFVPNLIKEKSQVQKTGEAAVVKVVESQA
QLYELDHDDEKPSLSELLSAGMITQKQISAYDNYYDQNKNEERNFND

Nucleotide

• Length: 384 bp

>NTDB_id=1007228 ABLU29_RS04045 WP_010906318.1 713428..713811(+) (comGC) [Lactococcus lactis strain 2B-5]
ATGGAAAGAACAAAGAAGTTTATTTTAAAAAAAATACAAAAAATATTTTTATTCGTTAAAATTTGTGAAAAAAAATGCCG
TCAGAAAGAGCTAAAAGCTTTTACTTTGATAGAGATGTTAATTGTACTAGCTATTATTAGTATTTTGATATTACTATTTG
TTCCAAATTTAATTAAAGAAAAATCACAAGTTCAAAAAACTGGAGAAGCGGCAGTTGTCAAAGTAGTAGAAAGTCAAGCT
CAACTTTATGAATTAGATCATGATGATGAGAAGCCGAGTCTGTCAGAATTGCTCAGTGCAGGGATGATTACTCAAAAACA
AATTTCTGCTTACGATAATTACTATGATCAGAATAAAAATGAAGAACGAAATTTTAATGACTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (32-52)

3D structure

• AlphaFold DB: A0A3N6KXZ7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Lactococcus lactis subsp. cremoris KW2	81.034	91.339	0.74
comGC/cglC	Streptococcus mitis SK321	56.436	79.528	0.449
comYC	Streptococcus mutans UA159	55.446	79.528	0.441
comYC	Streptococcus mutans UA140	55.446	79.528	0.441
comYC	Streptococcus gordonii str. Challis substr. CH1	56.566	77.953	0.441
comGC/cglC	Streptococcus pneumoniae TIGR4	54.455	79.528	0.433
comGC/cglC	Streptococcus pneumoniae Rx1	54.455	79.528	0.433
comGC/cglC	Streptococcus pneumoniae D39	54.455	79.528	0.433
comGC/cglC	Streptococcus pneumoniae R6	54.455	79.528	0.433
comGC/cglC	Streptococcus mitis NCTC 12261	58.427	70.079	0.409
comYC	Streptococcus suis isolate S10	56.818	69.291	0.394