Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01243  |
| T6SS type | Type i5 |
| Strain | Agrobacterium fabrum strain 12D13 |
| Replicon (RefSeq) | chromosome (NZ_CP033035) |
| Location | 1420086..1444587 |
| Function | anti-bacterial |
| Comment | T6SS exhibits antibacterial and secrete hcp activity |
| References | [1] Wu CF, Santos MNM, Cho ST, Chang HH, Tsai YM, Smith DA, Kuo CH, Chang JH, Lai EM. et al (2019) Plant-Pathogenic Agrobacterium tumefaciens Strains Have Diverse Type VI Effector-Immunity Pairs and Vary in In-Planta Competitiveness.. Mol Plant Microbe Interact. 32(8):961-971. [PudMed:30830835] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | Tae4 | TagF | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| At12D13_RS20875 (proP) | 1415802..1417322 | - | 1521 | WP_162991976.1 | glycine betaine/L-proline transporter ProP | ||
| At12D13_RS20880 | 1417488..1417784 | - | 297 | WP_006315910.1 | PRC-barrel domain-containing protein | ||
| At12D13_RS20885 | 1418049..1419185 | + | 1137 | WP_121691708.1 | polysaccharide export protein | ||
| At12D13_RS20890 | 1419194..1420099 | - | 906 | WP_162991977.1 | protein kinase | ||
| T6CP015583 | TagF | At12D13_RS20895 (tagF) | 1420086..1421501 | - | 1416 | WP_121691709.1 | type VI secretion system-associated protein TagF |
| T6CP015584 | TssM | At12D13_RS20900 (tssM) | 1421584..1425063 | - | 3480 | WP_121691710.1 | type VI secretion system membrane subunit TssM |
| T6CP015585 | TssL | At12D13_RS20905 (tssL) | 1425060..1426565 | - | 1506 | WP_121691711.1 | type VI secretion system protein TssL, long form |
| T6CP015586 | TssK | At12D13_RS20910 (tssK) | 1426562..1427902 | - | 1341 | WP_080813040.1 | type VI secretion system baseplate subunit TssK |
| At12D13_RS20915 | 1427892..1429091 | - | 1200 | WP_121691712.1 | type VI secretion system-associated FHA domain protein | ||
| T6CP015587 | TssG | At12D13_RS20920 (tssG) | 1429102..1430106 | - | 1005 | WP_121691713.1 | type VI secretion system baseplate subunit TssG |
| T6CP015588 | TssF | At12D13_RS20925 (tssF) | 1430116..1431897 | - | 1782 | WP_121691714.1 | type VI secretion system baseplate subunit TssF |
| T6CP015589 | TssE | At12D13_RS20930 (tssE) | 1431890..1432399 | - | 510 | WP_121691715.1 | type VI secretion system baseplate subunit TssE |
| At12D13_RS20935 | 1432392..1433216 | - | 825 | WP_121691716.1 | nitrogen fixation protein | ||
| T6CP015590 | TssC | At12D13_RS20940 (tssC) | 1433213..1434607 | - | 1395 | WP_121691717.1 | type VI secretion system contractile sheath large subunit |
| T6CP015591 | TssC | At12D13_RS20945 (tssC) | 1434662..1436143 | - | 1482 | WP_121691718.1 | type VI secretion system contractile sheath large subunit |
| T6CP015592 | TssB | At12D13_RS20950 (tssB) | 1436237..1436746 | - | 510 | WP_010973761.1 | type VI secretion system contractile sheath small subunit |
| T6CP015593 | TssA | At12D13_RS20955 (tssA) | 1436812..1437867 | - | 1056 | WP_010973762.1 | type VI secretion system protein TssA |
| T6CP015594 | TssH | At12D13_RS20960 (tssH) | 1438088..1440766 | + | 2679 | WP_121691719.1 | type VI secretion system ATPase TssH |
| T6CP015595 | TssD | At12D13_RS20965 | 1440824..1441300 | + | 477 | WP_003504561.1 | type VI secretion system tube protein Hcp |
| At12D13_RS20970 | 1441407..1441796 | + | 390 | WP_006315891.1 | hypothetical protein | ||
| T6CP015596 | Tae4 | At12D13_RS20975 | 1441808..1442308 | + | 501 | WP_006315890.1 | type VI secretion system amidase effector protein Tae4 |
| T6CP015597 | TssI | At12D13_RS20980 (tssI) | 1442323..1444587 | + | 2265 | WP_121691720.1 | type VI secretion system tip protein VgrG |
| At12D13_RS20985 | 1444601..1445710 | + | 1110 | WP_121691721.1 | DUF2169 domain-containing protein | ||
| At12D13_RS20990 | 1445707..1447287 | + | 1581 | WP_121691722.1 | DUF4150 domain-containing protein | ||
| At12D13_RS20995 | 1447290..1448021 | + | 732 | WP_121691723.1 | DUF1851 domain-containing protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| EFF01860 |
ATU_RS20360 (Tae4) | Tae | - | Agrobacterium fabrum strain 12D13 | chromosome (NZ_CP033035) | 1480980..1481480 (+) | 493359403 |
| EFF01859 |
At12D13_RS20965 (Hcp) | - | Agrobacterium fabrum strain 12D13 | chromosome (NZ_CP033035) | 1440824..1441300 (+) | 489600119 |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|