Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01103  |
| T6SS type | Type i5 |
| Strain | Agrobacterium tumefaciens strain 1D1609 |
| Replicon (RefSeq) | chromosome (NZ_CP026925) |
| Location | 1612910..1635897 |
| Function | anti-bacterial |
| Comment | Agrobacterium tumefaciens 1D1609 has a funtional T6SS and employs a nuclease effector as the major T6SS-dependent antibacterial toxin. The secretion assay showed hcp and vgrG remain active in secretion while null in ΔtssL mutant |
| References | [1] Wu CF, Santos MNM, Cho ST, Chang HH, Tsai YM, Smith DA, Kuo CH, Chang JH, Lai EM. et al (2019) Plant-Pathogenic Agrobacterium tumefaciens Strains Have Diverse Type VI Effector-Immunity Pairs and Vary in In-Planta Competitiveness.. Mol Plant Microbe Interact. 32(8):961-971. [PudMed:30830835] [2] Santos MNM, Cho ST, Wu CF, Chang CJ, Kuo CH, Lai EM. et al (2020) Redundancy and Specificity of Type VI Secretion vgrG Loci in Antibacterial Activity of Agrobacterium tumefaciens 1D1609 Strain.. Front Microbiol. 2.502777778. [PudMed:31993035] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssK | TssL | TssM |
| Number | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed. Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| IMU00350 |
At1D1609_44750 (v3a) | EFF01868 |
Agrobacterium tumefaciens strain 1D1609 | chromosome (NZ_CP026925) | 1638588..1639688 (+) | 1349686714 |
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|