Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00021  |
| T6SS type | Type i3 |
| Strain | Yersinia pestis CO92 |
| Replicon (RefSeq) | chromosome (NC_003143) |
| Location | 3272776..3302045 |
| Function | - |
| Comment | - |
| References | [1] Boyer F et al (2009) Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 0.488888889. [PudMed:19284603] |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | TagL | TssA | TssB | TssC | TssD | TssF | TssG | TssH | TssJ | TssK |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| YPO_RS15580 (tadA) | 3269085..3269687 | - | 603 | WP_002211563.1 | tRNA adenosine(34) deaminase TadA | ||
| YPO_RS15585 (yfhb) | 3269758..3270453 | - | 696 | WP_002211564.1 | phosphatidylglycerophosphatase C | ||
| YPO_RS15590 (murQ) | 3270680..3271567 | - | 888 | WP_002211565.1 | N-acetylmuramic acid 6-phosphate etherase | ||
| YPO_RS15595 | 3271775..3272614 | + | 840 | WP_002211566.1 | MurR/RpiR family transcriptional regulator | ||
| YPO_RS15600 | 3272776..3273036 | + | 261 | WP_002211567.1 | YfhL family 4Fe-4S dicluster ferredoxin | ||
| YPO_RS15605 (tnpA) | 3273192..3273650 | - | 459 | WP_002213775.1 | IS200/IS605-like element IS1541B family transposase | ||
| YPO_RS15610 | 3273852..3274232 | - | 381 | WP_002211568.1 | holo-ACP synthase | ||
| YPO_RS15615 (pdxJ) | 3274232..3274963 | - | 732 | WP_002211569.1 | pyridoxine 5'-phosphate synthase | ||
| YPO_RS15620 (istB) | 3275153..3275932 | - | 780 | WP_001297096.1 | IS21-like element IS100kyp family helper ATPase IstB | ||
| YPO_RS15625 (istA) | 3275932..3276954 | - | 1023 | WP_000255944.1 | IS21-like element IS100 family transposase | ||
| YPO_RS15630 | 3277040..3277636 | - | 597 | pseudogene | DotU family type IV/VI secretion system protein | ||
| T6CP000156 | TssK | YPO_RS15635 (tssK) | 3277633..3278982 | - | 1350 | WP_002211571.1 | type VI secretion system baseplate subunit TssK |
| T6CP000157 | TssJ | YPO_RS15640 (tssJ) | 3278986..3279525 | - | 540 | WP_002211572.1 | type VI secretion system lipoprotein TssJ |
| T6CP000158 | TssD | YPO_RS15645 | 3279799..3280284 | - | 486 | WP_002211573.1 | type VI secretion system tube protein Hcp |
| T6CP000159 | TssC | YPO_RS15650 (tssC) | 3280610..3282112 | - | 1503 | WP_002211574.1 | type VI secretion system contractile sheath large subunit |
| T6CP000160 | TssB | YPO_RS15655 (tssB) | 3282136..3282660 | - | 525 | WP_002211575.1 | type VI secretion system contractile sheath small subunit |
| YPO_RS15660 | 3282765..3283373 | - | 609 | WP_002211576.1 | type 1 fimbrial protein | ||
| YPO_RS15665 | 3283358..3284548 | - | 1191 | WP_002211577.1 | fimbrial biogenesis outer membrane usher protein | ||
| YPO_RS15670 | 3284573..3285781 | + | 1209 | WP_002209743.1 | IS256 family transposase | ||
| YPO_RS15675 | 3285803..3287353 | - | 1551 | WP_002215157.1 | fimbrial biogenesis outer membrane usher protein | ||
| YPO_RS15680 | 3287481..3288242 | - | 762 | WP_002211579.1 | fimbria/pilus periplasmic chaperone | ||
| YPO_RS15685 | 3288399..3288944 | - | 546 | WP_002211580.1 | type 1 fimbrial protein | ||
| T6CP000161 | TssH | YPO_RS15690 (tssH) | 3289145..3291820 | - | 2676 | WP_002215317.1 | type VI secretion system ATPase TssH |
| T6CP000162 | TssF | YPO_RS15695 (tssF) | 3292603..3294483 | + | 1881 | WP_002211582.1 | type VI secretion system baseplate subunit TssF |
| T6CP000163 | TssG | YPO_RS15700 (tssG) | 3294483..3295508 | + | 1026 | WP_002211583.1 | type VI secretion system baseplate subunit TssG |
| T6CP000164 | TssA | YPO_RS15705 | 3295607..3296788 | + | 1182 | WP_002211584.1 | ImpA family type VI secretion system protein |
| YPO_RS15710 | 3296795..3297826 | + | 1032 | WP_002215319.1 | fimbrial protein | ||
| YPO_RS15715 | 3297866..3299203 | + | 1338 | WP_002211586.1 | glycosyl transferase | ||
| YPO_RS15720 | 3299200..3299883 | + | 684 | WP_002211587.1 | hypothetical protein | ||
| T6CP011409 | TagL | YPO_RS15725 | 3299884..3301566 | + | 1683 | WP_002211588.1 | OmpA family protein |
| YPO_RS15730 | 3301563..3302045 | + | 483 | WP_002215321.1 | DcrB-related protein | ||
| YPO_RS15735 | 3302403..3303005 | - | 603 | WP_002211590.1 | LuxR family transcriptional regulator | ||
| YPO_RS15740 (mltB) | 3304260..3305354 | - | 1095 | WP_002211594.1 | lytic murein transglycosylase B | ||
| YPO_RS15745 | 3305683..3306702 | + | 1020 | WP_002211596.1 | iron ABC transporter substrate-binding protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|