Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   ABC814_RS10295 Genome accession   NZ_CP155533
Coordinates   1978511..1978834 (-) Length   107 a.a.
NCBI ID   WP_000738628.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Spn1439-106     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1973511..1983834
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC814_RS10260 (ABC814_10260) comYH 1973651..1974604 (-) 954 WP_000345132.1 class I SAM-dependent methyltransferase Machinery gene
  ABC814_RS10265 (ABC814_10265) - 1974950..1975752 (+) 803 Protein_1998 IS5 family transposase -
  ABC814_RS10270 (ABC814_10270) - 1975903..1976379 (+) 477 WP_000777686.1 GNAT family N-acetyltransferase -
  ABC814_RS10275 (ABC814_10275) comGG/cglG 1977034..1977447 (-) 414 WP_000265615.1 competence type IV pilus minor pilin ComGG Machinery gene
  ABC814_RS10280 (ABC814_10280) comGF/cglF 1977425..1977886 (-) 462 WP_000250520.1 competence type IV pilus minor pilin ComGF Machinery gene
  ABC814_RS10285 (ABC814_10285) comGE/cglE 1977849..1978151 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  ABC814_RS10290 (ABC814_10290) comGD/cglD 1978114..1978548 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  ABC814_RS10295 (ABC814_10295) comGC/cglC 1978511..1978834 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  ABC814_RS10300 (ABC814_10300) comGB/cglB 1978836..1979852 (-) 1017 WP_078141518.1 competence type IV pilus assembly protein ComGB Machinery gene
  ABC814_RS10305 (ABC814_10305) comGA/cglA/cilD 1979800..1980741 (-) 942 WP_000249572.1 competence type IV pilus ATPase ComGA Machinery gene
  ABC814_RS10310 (ABC814_10310) - 1980817..1981182 (-) 366 WP_000286415.1 DUF1033 family protein -
  ABC814_RS10315 (ABC814_10315) - 1981333..1982391 (-) 1059 WP_000649465.1 zinc-dependent alcohol dehydrogenase family protein -
  ABC814_RS10320 (ABC814_10320) nagA 1982554..1983705 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence


Protein


Download         Length: 107 a.a.        Molecular weight: 12232.41 Da        Isoelectric Point: 9.8887

>NTDB_id=997203 ABC814_RS10295 WP_000738628.1 1978511..1978834(-) (comGC/cglC) [Streptococcus pneumoniae strain Spn1439-106]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQD
DGRITEEQAKAYKEYHDKQNTSQIVKD

Nucleotide


Download         Length: 324 bp        

>NTDB_id=997203 ABC814_RS10295 WP_000738628.1 1978511..1978834(-) (comGC/cglC) [Streptococcus pneumoniae strain Spn1439-106]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGAAAGTTACAAGAC
GATGGACGCATCACGGAAGAACAGGCTAAAGCCTATAAAGAATACCATGATAAACAAAATACTAGTCAAATCGTTAAAGA
TTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

93.458

100

0.935

  comGC/cglC Streptococcus pneumoniae D39

94.175

96.262

0.907

  comGC/cglC Streptococcus pneumoniae R6

94.175

96.262

0.907

  comGC/cglC Streptococcus pneumoniae Rx1

94.175

96.262

0.907

  comGC/cglC Streptococcus pneumoniae TIGR4

93.204

96.262

0.897

  comGC/cglC Streptococcus mitis SK321

88.35

96.262

0.85

  comYC Streptococcus gordonii str. Challis substr. CH1

69.388

91.589

0.636

  comYC Streptococcus mutans UA140

64.211

88.785

0.57

  comYC Streptococcus mutans UA159

64.211

88.785

0.57

  comYC Streptococcus suis isolate S10

69.136

75.701

0.523

  comGC Lactococcus lactis subsp. cremoris KW2

54.639

90.654

0.495

  comGC Staphylococcus aureus MW2

48.837

80.374

0.393

  comGC Staphylococcus aureus N315

48.837

80.374

0.393

  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

80.374

0.364


Multiple sequence alignment