Detailed information
Bioinformatically predicted
Overview
| Name | comX/comX2 | Type | Regulator |
| Locus tag | ABC810_RS11045 | Genome accession | NZ_CP155532 |
| Coordinates | 2172673..2173152 (-) | Length | 159 a.a. |
| NCBI ID | WP_000588897.1 | Uniprot ID | Q9R2W8 |
| Organism | Streptococcus pneumoniae strain SP264 | ||
| Function | activate transcription of late competence genes (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 2127184..2176655 | 2172673..2173152 | within | 0 |
| IS/Tn | 2173375..2174631 | 2172673..2173152 | flank | 223 |
Gene organization within MGE regions
Location: 2127184..2176655
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ABC810_RS10785 (ABC810_10790) | purH | 2127184..2128731 (-) | 1548 | WP_000167083.1 | bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | - |
| ABC810_RS10790 (ABC810_10795) | - | 2128756..2129265 (-) | 510 | WP_000894018.1 | VanZ family protein | - |
| ABC810_RS10795 (ABC810_10800) | purN | 2129349..2129894 (-) | 546 | WP_000717506.1 | phosphoribosylglycinamide formyltransferase | - |
| ABC810_RS10800 (ABC810_10805) | purM | 2129891..2130913 (-) | 1023 | WP_000182575.1 | phosphoribosylformylglycinamidine cyclo-ligase | - |
| ABC810_RS10805 (ABC810_10810) | purF | 2130950..2132392 (-) | 1443 | WP_000220632.1 | amidophosphoribosyltransferase | - |
| ABC810_RS10810 (ABC810_10815) | - | 2132485..2136210 (-) | 3726 | WP_000361217.1 | phosphoribosylformylglycinamidine synthase | - |
| ABC810_RS10815 (ABC810_10820) | purC | 2136267..2136974 (-) | 708 | WP_000043310.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
| ABC810_RS10820 (ABC810_10825) | comB | 2137144..2138493 (-) | 1350 | WP_000801611.1 | competence pheromone export protein ComB | Regulator |
| ABC810_RS10825 (ABC810_10830) | comA | 2138506..2140659 (-) | 2154 | WP_000668272.1 | peptide cleavage/export ABC transporter ComA | Regulator |
| ABC810_RS10830 (ABC810_10835) | - | 2141246..2141371 (-) | 126 | WP_000346297.1 | PncF family bacteriocin immunity protein | - |
| ABC810_RS10835 (ABC810_10840) | blpU | 2141374..2141604 (-) | 231 | WP_001093075.1 | bacteriocin-like peptide BlpU | - |
| ABC810_RS10840 (ABC810_10845) | - | 2141806..2142097 (-) | 292 | Protein_2101 | IS5/IS1182 family transposase | - |
| ABC810_RS10845 (ABC810_10850) | - | 2142143..2142376 (-) | 234 | WP_000136449.1 | acyl carrier protein | - |
| ABC810_RS10850 (ABC810_10855) | plsX | 2142382..2143374 (-) | 993 | WP_000717451.1 | phosphate acyltransferase PlsX | - |
| ABC810_RS10855 (ABC810_10860) | recO | 2143371..2144141 (-) | 771 | WP_000616164.1 | DNA repair protein RecO | - |
| ABC810_RS10860 (ABC810_10865) | - | 2144138..2145307 (-) | 1170 | WP_000366348.1 | pyridoxal phosphate-dependent aminotransferase | - |
| ABC810_RS10865 (ABC810_10870) | - | 2145456..2146466 (+) | 1011 | WP_000009180.1 | YeiH family protein | - |
| ABC810_RS10870 (ABC810_10875) | - | 2146485..2146700 (-) | 216 | WP_001814139.1 | hypothetical protein | - |
| ABC810_RS10875 (ABC810_10880) | - | 2146741..2147178 (-) | 438 | WP_000076479.1 | CoA-binding protein | - |
| ABC810_RS10880 (ABC810_10885) | polA | 2147263..2149896 (-) | 2634 | WP_001812055.1 | DNA polymerase I | - |
| ABC810_RS10885 (ABC810_10890) | - | 2150505..2151432 (-) | 928 | Protein_2110 | Rpn family recombination-promoting nuclease/putative transposase | - |
| ABC810_RS10890 (ABC810_10895) | - | 2151550..2152518 (-) | 969 | WP_000010163.1 | ribose-phosphate diphosphokinase | - |
| ABC810_RS10895 (ABC810_10900) | - | 2152663..2153446 (-) | 784 | Protein_2112 | PrsW family glutamic-type intramembrane protease | - |
| ABC810_RS10900 (ABC810_10905) | - | 2153471..2153968 (-) | 498 | WP_001809263.1 | carbonic anhydrase | - |
| ABC810_RS10905 (ABC810_10910) | radA | 2154041..2155402 (-) | 1362 | WP_075213698.1 | DNA repair protein RadA | Machinery gene |
| ABC810_RS10910 (ABC810_10915) | - | 2155416..2155931 (-) | 516 | WP_000691236.1 | histidine phosphatase family protein | - |
| ABC810_RS10915 (ABC810_10920) | - | 2155933..2156376 (-) | 444 | WP_000701992.1 | dUTP diphosphatase | - |
| ABC810_RS10920 (ABC810_10925) | - | 2156681..2156830 (+) | 150 | WP_001030863.1 | hypothetical protein | - |
| ABC810_RS10925 (ABC810_10930) | - | 2156972..2157151 (+) | 180 | WP_001209433.1 | hypothetical protein | - |
| ABC810_RS10930 (ABC810_10935) | - | 2157371..2157736 (-) | 366 | Protein_2119 | autolysin | - |
| ABC810_RS10935 (ABC810_10940) | - | 2157756..2157923 (+) | 168 | WP_000024181.1 | YjzC family protein | - |
| ABC810_RS10940 (ABC810_10945) | - | 2158078..2158281 (-) | 204 | WP_001247549.1 | hypothetical protein | - |
| ABC810_RS10945 (ABC810_10950) | - | 2158304..2158495 (-) | 192 | WP_001112859.1 | DNA-binding protein | - |
| ABC810_RS10950 (ABC810_10955) | - | 2159067..2159435 (+) | 369 | WP_000464160.1 | helix-turn-helix transcriptional regulator | - |
| ABC810_RS10955 (ABC810_10960) | - | 2159435..2159668 (+) | 234 | WP_000156419.1 | hypothetical protein | - |
| ABC810_RS10960 (ABC810_10965) | - | 2159668..2159931 (+) | 264 | WP_000285962.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| ABC810_RS10965 (ABC810_10970) | - | 2159944..2160324 (+) | 381 | WP_000170931.1 | ImmA/IrrE family metallo-endopeptidase | - |
| ABC810_RS10970 (ABC810_10975) | - | 2160341..2161411 (+) | 1071 | WP_000401841.1 | type I restriction endonuclease | - |
| ABC810_RS10975 (ABC810_10980) | - | 2161472..2161819 (+) | 348 | WP_001839379.1 | hypothetical protein | - |
| ABC810_RS10980 (ABC810_10985) | - | 2161909..2162607 (+) | 699 | WP_001106362.1 | site-specific integrase | - |
| ABC810_RS10990 (ABC810_10995) | tadA | 2162816..2163283 (-) | 468 | WP_000291870.1 | tRNA adenosine(34) deaminase TadA | - |
| ABC810_RS10995 (ABC810_11000) | - | 2163484..2164770 (-) | 1287 | WP_000205044.1 | adenylosuccinate synthase | - |
| ABC810_RS11000 (ABC810_11005) | comW | 2165001..2165237 (-) | 237 | WP_000939545.1 | sigma(X)-activator ComW | Regulator |
| ABC810_RS11005 (ABC810_11010) | - | 2165503..2166300 (+) | 798 | Protein_2133 | transposase | - |
| ABC810_RS11010 (ABC810_11015) | - | 2166335..2167181 (-) | 847 | Protein_2134 | IS630 family transposase | - |
| ABC810_RS11045 (ABC810_11050) | comX/comX2 | 2172673..2173152 (-) | 480 | WP_000588897.1 | sigma-70 family RNA polymerase sigma factor | Regulator |
| ABC810_RS11050 (ABC810_11055) | - | 2173375..2174631 (+) | 1257 | WP_000436644.1 | ISL3 family transposase | - |
| ABC810_RS11055 (ABC810_11060) | ftsH | 2174697..2176655 (-) | 1959 | WP_000744545.1 | ATP-dependent zinc metalloprotease FtsH | - |
Sequence
Protein
Download Length: 159 a.a. Molecular weight: 19873.52 Da Isoelectric Point: 7.3797
>NTDB_id=997142 ABC810_RS11045 WP_000588897.1 2172673..2173152(-) (comX/comX2) [Streptococcus pneumoniae strain SP264]
MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH
MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH
Nucleotide
Download Length: 480 bp
>NTDB_id=997142 ABC810_RS11045 WP_000588897.1 2172673..2173152(-) (comX/comX2) [Streptococcus pneumoniae strain SP264]
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
ATCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAGA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGATCAGTCATCGTATAAGTGAGGGGGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCACTAG
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
ATCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAGA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGATCAGTCATCGTATAAGTGAGGGGGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCACTAG
Domains
No domain identified.
Similar proteins
Only experimentally validated proteins are listed.