Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   AAFQ93_RS00720 Genome accession   NZ_CP152419
Coordinates   161633..162574 (-) Length   313 a.a.
NCBI ID   WP_375555364.1    Uniprot ID   -
Organism   Streptococcus nidrosiense strain SO-23-1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 156633..167574
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAFQ93_RS00685 (AAFQ93_00685) - 158033..158734 (-) 702 WP_000179052.1 histidine phosphatase family protein -
  AAFQ93_RS00690 (AAFQ93_00690) comGG/cglG 158844..159281 (-) 438 WP_223140197.1 competence type IV pilus minor pilin ComGG Machinery gene
  AAFQ93_RS00695 (AAFQ93_00695) comGF/cglF 159259..159720 (-) 462 WP_223140198.1 competence type IV pilus minor pilin ComGF Machinery gene
  AAFQ93_RS00700 (AAFQ93_00700) comGE/cglE 159683..159985 (-) 303 WP_223140199.1 competence type IV pilus minor pilin ComGE Machinery gene
  AAFQ93_RS00705 (AAFQ93_00705) comGD/cglD 159948..160382 (-) 435 WP_375555362.1 competence type IV pilus minor pilin ComGD Machinery gene
  AAFQ93_RS00710 (AAFQ93_00710) comGC/cglC 160345..160668 (-) 324 WP_375555363.1 competence type IV pilus major pilin ComGC Machinery gene
  AAFQ93_RS00715 (AAFQ93_00715) comGB/cglB 160669..161712 (-) 1044 WP_223141129.1 competence type IV pilus assembly protein ComGB Machinery gene
  AAFQ93_RS00720 (AAFQ93_00720) comGA/cglA/cilD 161633..162574 (-) 942 WP_375555364.1 competence type IV pilus ATPase ComGA Machinery gene
  AAFQ93_RS00725 (AAFQ93_00725) - 162633..163010 (-) 378 WP_223140241.1 DUF1033 family protein -
  AAFQ93_RS00730 (AAFQ93_00730) - 163147..164205 (-) 1059 WP_375555365.1 zinc-dependent alcohol dehydrogenase family protein -
  AAFQ93_RS00735 (AAFQ93_00735) nagA 164346..165497 (-) 1152 WP_049509183.1 N-acetylglucosamine-6-phosphate deacetylase -
  AAFQ93_RS00740 (AAFQ93_00740) - 166089..167345 (+) 1257 WP_375555366.1 ISL3 family transposase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35399.48 Da        Isoelectric Point: 6.4324

>NTDB_id=989137 AAFQ93_RS00720 WP_375555364.1 161633..162574(-) (comGA/cglA/cilD) [Streptococcus nidrosiense strain SO-23-1]
MVQTLAQELITLAKKQGAQDIYFVPKEKIYELHMRVGDERHLINTYDFEKLGAVISHFKFIAGMNVGEKRRSQLGSCDYQ
HGDKVSSLRLSTVGDYRGHESLVIRLLHDQEQELRFWFQDLIELEKGFRQRGLYLFAGPVGSGKTTLMHELAKSLFKGQQ
VMSIEDPVEIKQEAMLQLQLNEAIGLSYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSVRGVY
ERLLELGVSEDELAVVLQGVCYQRLIGGGGIIDFANGNYQEHQAEKWNGQIDQLLKEGHITALQAETEKISYQ

Nucleotide


Download         Length: 942 bp        

>NTDB_id=989137 AAFQ93_RS00720 WP_375555364.1 161633..162574(-) (comGA/cglA/cilD) [Streptococcus nidrosiense strain SO-23-1]
ATGGTACAAACACTTGCACAAGAATTGATTACACTGGCCAAAAAACAAGGAGCTCAGGACATCTATTTTGTTCCTAAAGA
AAAGATTTATGAGCTACATATGCGAGTTGGAGATGAGAGACATTTGATTAACACCTATGACTTTGAAAAGTTGGGGGCTG
TCATTAGTCATTTTAAGTTTATTGCGGGGATGAACGTTGGAGAAAAACGCCGTAGTCAGCTTGGTTCCTGTGATTATCAG
CATGGAGATAAGGTTTCTTCATTACGCTTATCGACGGTGGGAGATTATCGTGGTCATGAGAGTCTAGTAATCCGGCTTTT
GCATGATCAAGAACAAGAGTTGCGCTTCTGGTTTCAGGACCTTATAGAACTGGAAAAGGGCTTTAGGCAACGCGGGCTTT
ATCTTTTTGCAGGCCCCGTAGGAAGCGGCAAAACTACTTTGATGCATGAATTAGCCAAGTCATTGTTTAAGGGACAACAG
GTCATGTCCATTGAAGATCCGGTTGAGATTAAGCAAGAAGCAATGCTACAATTACAGCTCAATGAAGCTATCGGACTGAG
CTATGAAAACTTGATAAAACTTTCCCTACGACATCGTCCAGATCTTTTAATCATTGGAGAAATCAGGGATAGTGAAACAG
CCCGTGCTGTTGTACGAGCTAGTCTGACAGGTGCCACGGTATTCTCGACAATCCATGCCAAGAGTGTTCGTGGTGTCTAT
GAGCGTCTTTTAGAACTGGGTGTCAGTGAAGATGAACTAGCAGTTGTTTTACAAGGCGTATGCTACCAGAGGTTAATCGG
GGGAGGAGGAATTATTGATTTTGCAAATGGAAATTATCAAGAACACCAGGCAGAAAAGTGGAATGGACAAATTGACCAGC
TTCTTAAAGAAGGACATATCACTGCCCTTCAAGCTGAAACGGAGAAAATTAGCTACCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(12-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

85.577

99.681

0.853
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

85.256

99.681

0.85
  comGA/cglA/cilD Streptococcus pneumoniae D39

85.256

99.681

0.85
  comGA/cglA/cilD Streptococcus pneumoniae R6

85.256

99.681

0.85
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

85.256

99.681

0.85
  comYA Streptococcus gordonii str. Challis substr. CH1

76.997

100

0.77
  comYA Streptococcus mutans UA159

63.987

99.361

0.636
  comYA Streptococcus mutans UA140

63.987

99.361

0.636
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

63.226

99.042

0.626
  comGA Lactococcus lactis subsp. cremoris KW2

57.188

100

0.572
  comGA Latilactobacillus sakei subsp. sakei 23K

43.885

88.818

0.39

Multiple sequence alignment