Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   R8568_RS09765 Genome accession   NZ_AP026931
Coordinates   1900318..1901259 (-) Length   313 a.a.
NCBI ID   WP_000249567.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900701541     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1895318..1906259
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8568_RS09725 (PC1520_18930) comYH 1895804..1896757 (-) 954 WP_000345101.1 class I SAM-dependent methyltransferase Machinery gene
  R8568_RS09730 - 1896818..1897412 (-) 595 Protein_1892 class I SAM-dependent methyltransferase -
  R8568_RS09735 (PC1520_18960) comGG/cglG 1897549..1897962 (-) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8568_RS09740 (PC1520_18970) comGF/cglF 1897940..1898401 (-) 462 WP_000250542.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8568_RS09745 (PC1520_18980) comGE/cglE 1898364..1898666 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8568_RS09750 (PC1520_18990) comGD/cglD 1898629..1899033 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8568_RS09755 (PC1520_19000) comGC/cglC 1899026..1899352 (-) 327 WP_000738626.1 comG operon protein ComGC Machinery gene
  R8568_RS09760 (PC1520_19010) comGB/cglB 1899354..1900370 (-) 1017 WP_078375398.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8568_RS09765 (PC1520_19020) comGA/cglA/cilD 1900318..1901259 (-) 942 WP_000249567.1 competence type IV pilus ATPase ComGA Machinery gene
  R8568_RS09770 (PC1520_19030) - 1901335..1901700 (-) 366 WP_000286415.1 DUF1033 family protein -
  R8568_RS09775 (PC1520_19040) - 1901851..1902909 (-) 1059 WP_000649473.1 zinc-dependent alcohol dehydrogenase family protein -
  R8568_RS09780 (PC1520_19050) nagA 1903072..1904223 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  R8568_RS09785 (PC1520_19060) - 1904376..1906193 (-) 1818 WP_001220920.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35573.48 Da        Isoelectric Point: 6.0083

>NTDB_id=98854 R8568_RS09765 WP_000249567.1 1900318..1901259(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain PZ900701541]
MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKIASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFANRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=98854 R8568_RS09765 WP_000249567.1 1900318..1901259(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain PZ900701541]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCAGCTCGGAAAAAAGGGACGCAGGATATCTATTTTGTCCCTAAGTT
AGACGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATAGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACCTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTTTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAACAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

99.361

100

0.994
  comGA/cglA/cilD Streptococcus pneumoniae D39

99.361

100

0.994
  comGA/cglA/cilD Streptococcus pneumoniae R6

99.361

100

0.994
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

99.361

100

0.994
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

96.486

100

0.965
  comYA Streptococcus gordonii str. Challis substr. CH1

77.742

99.042

0.77
  comYA Streptococcus mutans UA159

65.916

99.361

0.655
  comYA Streptococcus mutans UA140

65.916

99.361

0.655
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.581

99.042

0.62
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

99.681

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

42.642

84.665

0.361

Multiple sequence alignment