Detailed information NTG0098849

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: R8568_RS09740
• Genome accession: NZ_AP026931
• Coordinates: 1897940..1898401 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250542.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900701541
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1892940..1903401

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8568_RS09705 (PC1520_18900)	-	1893244..1894068 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
R8568_RS09710 (PC1520_18910)	rnpA	1894043..1894414 (-)	372	WP_000739246.1	ribonuclease P protein component	-
R8568_RS09715	-	1894431..1894562 (-)	132	WP_000768904.1	hypothetical protein	-
R8568_RS09720 (PC1520_18920)	-	1894563..1895753 (-)	1191	WP_000167766.1	acetate kinase	-
R8568_RS09725 (PC1520_18930)	comYH	1895804..1896757 (-)	954	WP_000345101.1	class I SAM-dependent methyltransferase	Machinery gene
R8568_RS09730	-	1896818..1897412 (-)	595	Protein_1892	class I SAM-dependent methyltransferase	-
R8568_RS09735 (PC1520_18960)	comGG/cglG	1897549..1897962 (-)	414	WP_000265624.1	competence type IV pilus minor pilin ComGG	Machinery gene
R8568_RS09740 (PC1520_18970)	comGF/cglF	1897940..1898401 (-)	462	WP_000250542.1	competence type IV pilus minor pilin ComGF	Machinery gene
R8568_RS09745 (PC1520_18980)	comGE/cglE	1898364..1898666 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R8568_RS09750 (PC1520_18990)	comGD/cglD	1898629..1899033 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
R8568_RS09755 (PC1520_19000)	comGC/cglC	1899026..1899352 (-)	327	WP_000738626.1	comG operon protein ComGC	Machinery gene
R8568_RS09760 (PC1520_19010)	comGB/cglB	1899354..1900370 (-)	1017	WP_078375398.1	competence type IV pilus assembly protein ComGB	Machinery gene
R8568_RS09765 (PC1520_19020)	comGA/cglA/cilD	1900318..1901259 (-)	942	WP_000249567.1	competence type IV pilus ATPase ComGA	Machinery gene
R8568_RS09770 (PC1520_19030)	-	1901335..1901700 (-)	366	WP_000286415.1	DUF1033 family protein	-
R8568_RS09775 (PC1520_19040)	-	1901851..1902909 (-)	1059	WP_000649473.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17918.53 Da
• Isoelectric Point: 9.3137

>NTDB_id=98849 R8568_RS09740 WP_000250542.1 1897940..1898401(-) (comGF/cglF) [Streptococcus pneumoniae strain PZ900701541]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=98849 R8568_RS09740 WP_000250542.1 1897940..1898401(-) (comGF/cglF) [Streptococcus pneumoniae strain PZ900701541]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae D39	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae R6	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae TIGR4	96.078	100	0.961
comGF/cglF	Streptococcus mitis SK321	92.157	100	0.922
comGF/cglF	Streptococcus mitis NCTC 12261	90.85	100	0.909