Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   NYE32_RS09560 Genome accession   NZ_CP150201
Coordinates   2060318..2061259 (-) Length   313 a.a.
NCBI ID   WP_002885658.1    Uniprot ID   -
Organism   Streptococcus sp. FSL R7-0248     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2055318..2066259
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE32_RS09520 (NYE32_09520) - 2055393..2056586 (-) 1194 WP_073689934.1 acetate kinase -
  NYE32_RS09525 (NYE32_09525) comYH 2056643..2057599 (-) 957 WP_073689935.1 class I SAM-dependent methyltransferase Machinery gene
  NYE32_RS09530 (NYE32_09530) comGG 2057644..2057961 (-) 318 WP_060973072.1 competence type IV pilus minor pilin ComGG -
  NYE32_RS09535 (NYE32_09535) comYF 2057939..2058376 (-) 438 WP_037600123.1 competence type IV pilus minor pilin ComGF Machinery gene
  NYE32_RS09540 (NYE32_09540) comGE 2058363..2058653 (-) 291 WP_073689936.1 competence type IV pilus minor pilin ComGE -
  NYE32_RS09545 (NYE32_09545) comYD 2058625..2059053 (-) 429 WP_253183867.1 competence type IV pilus minor pilin ComGD Machinery gene
  NYE32_RS09550 (NYE32_09550) comYC 2059013..2059339 (-) 327 WP_070576715.1 competence type IV pilus major pilin ComGC Machinery gene
  NYE32_RS09555 (NYE32_09555) comYB 2059336..2060436 (-) 1101 WP_142236643.1 competence type IV pilus assembly protein ComGB Machinery gene
  NYE32_RS09560 (NYE32_09560) comYA 2060318..2061259 (-) 942 WP_002885658.1 competence type IV pilus ATPase ComGA Machinery gene
  NYE32_RS09565 (NYE32_09565) - 2061340..2061702 (-) 363 WP_002887019.1 DUF1033 family protein -
  NYE32_RS09570 (NYE32_09570) rpoC 2061858..2065496 (-) 3639 WP_070437474.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35283.27 Da        Isoelectric Point: 5.4492

>NTDB_id=966199 NYE32_RS09560 WP_002885658.1 2060318..2061259(-) (comYA) [Streptococcus sp. FSL R7-0248]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGQRVSLRLSTVGDYRGLESLVIRVLHSERRELVYWNQGIQPIMDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDNLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSVAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFASENFQSHSSTSWNQQLEGLVQQGYLTEGDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=966199 NYE32_RS09560 WP_002885658.1 2060318..2061259(-) (comYA) [Streptococcus sp. FSL R7-0248]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTACGAGCTCTATATGCGAGTTGGCCAGGAGAGGAGATTAATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTAGGTTCCTGTGACTATGAT
TGTGGTGATGGTCAAAGGGTTTCTCTGCGTTTATCAACCGTTGGGGATTATCGCGGCTTAGAAAGTTTAGTTATTCGTGT
TCTACATTCCGAACGTCGAGAATTGGTGTATTGGAATCAAGGAATCCAGCCGATTATGGATGCTTTGGATTATCGTGGCT
TGTATCTCTTTGCAGGTCCCGTAGGTTCTGGAAAGACTACGCTTATGCATGAATTGGTTCAGGAGCGTTTTAAGGGACAG
CAGGTGATTTCGATTGAAGATCCTGTGGAAATTAAACAGGATAATGTCTTGCAACTCCAGGTAAATCAGGCAATTGACAT
GACCTATGATAATTTGATTAAGCTATCACTACGTCACCGCCCGGATGTTTTGATTATTGGAGAAATTCGAGATAAGGAGA
CTGCTCGAGCGGTTATTAGAGCTAGTCTGACAGGAGTGACTGTTCTTTCAACTATTCACGCAAAGAGTGTGGCAGGTGTT
TATGAGCGTCTTCTGGACCTTGGTGTAGATAAGTCTGAGTTGGATAATGCTCTTCAAGGGATTGCCTATATGCGTTTGAT
TAAGGGAGGAGGTGTGATTGATTTTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAACAGTTGGAAG
GCTTGGTTCAACAAGGATATCTCACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

65.176

100

0.652
  comYA Streptococcus mutans UA140

65.176

100

0.652
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.595

99.361

0.652
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.309

99.361

0.639
  comYA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.897

99.681

0.607
  comGA Lactococcus lactis subsp. cremoris KW2

51.447

99.361

0.511
  comGA Latilactobacillus sakei subsp. sakei 23K

41.697

86.581

0.361

Multiple sequence alignment