Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   V6U69_RS00715 Genome accession   NZ_CP145867
Coordinates   132021..132962 (+) Length   313 a.a.
NCBI ID   WP_002885658.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS10     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 127021..137962
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U69_RS00705 (V6U69_00705) rpoC 127785..131423 (+) 3639 WP_002887020.1 DNA-directed RNA polymerase subunit beta' -
  V6U69_RS00710 (V6U69_00710) - 131579..131941 (+) 363 WP_002885749.1 DUF1033 family protein -
  V6U69_RS00715 (V6U69_00715) comYA 132021..132962 (+) 942 WP_002885658.1 competence type IV pilus ATPase ComGA Machinery gene
  V6U69_RS00720 (V6U69_00720) comYB 132844..133944 (+) 1101 WP_155115607.1 competence type IV pilus assembly protein ComGB Machinery gene
  V6U69_RS00725 (V6U69_00725) comYC 133953..134267 (+) 315 WP_037611125.1 competence type IV pilus major pilin ComGC Machinery gene
  V6U69_RS00730 (V6U69_00730) comYD 134227..134655 (+) 429 WP_260312930.1 competence type IV pilus minor pilin ComGD Machinery gene
  V6U69_RS00735 (V6U69_00735) comGE 134687..134917 (+) 231 WP_002887015.1 competence type IV pilus minor pilin ComGE -
  V6U69_RS00740 (V6U69_00740) comYF 134904..135341 (+) 438 WP_022496100.1 competence type IV pilus minor pilin ComGF Machinery gene
  V6U69_RS00745 (V6U69_00745) comGG 135319..135636 (+) 318 WP_021144683.1 competence type IV pilus minor pilin ComGG -
  V6U69_RS00750 (V6U69_00750) comYH 135681..136637 (+) 957 WP_410533909.1 class I SAM-dependent methyltransferase Machinery gene
  V6U69_RS00755 (V6U69_00755) - 136694..137887 (+) 1194 WP_410533911.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35283.27 Da        Isoelectric Point: 5.4492

>NTDB_id=940755 V6U69_RS00715 WP_002885658.1 132021..132962(+) (comYA) [Streptococcus salivarius strain KSS10]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGQRVSLRLSTVGDYRGLESLVIRVLHSERRELVYWNQGIQPIMDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDNLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSVAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFASENFQSHSSTSWNQQLEGLVQQGYLTEGDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=940755 V6U69_RS00715 WP_002885658.1 132021..132962(+) (comYA) [Streptococcus salivarius strain KSS10]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTACGAGCTCTATATGCGAGTTGGCCAGGAGAGGAGATTAATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTAGGTTCCTGTGACTATGAT
TGTGGTGATGGTCAAAGGGTTTCTCTGCGTTTGTCTACCGTTGGGGATTATCGCGGCTTAGAAAGTTTAGTTATTCGTGT
TCTACATTCTGAACGTCGAGAATTAGTGTACTGGAATCAAGGAATCCAGCCTATTATGGATGCTTTGGATTATCGTGGCT
TATATCTCTTTGCAGGTCCCGTTGGTTCTGGAAAGACTACGCTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTGATTTCGATTGAGGACCCTGTGGAAATTAAACAGGATAATGTTTTGCAACTCCAGGTGAATCAAGCAATTGACAT
GACCTATGATAATTTGATTAAGCTATCATTACGTCACCGCCCGGATGTTTTGATTATTGGAGAGATTCGAGATAAGGAGA
CTGCTCGAGCGGTTATTAGAGCTAGTCTGACGGGAGTGACTGTTCTTTCAACTATTCACGCAAAGAGTGTGGCAGGTGTT
TATGAGCGTCTTCTGGACCTCGGTGTAGATAAGTCTGAGTTGGATAATGCTCTTCAAGGGATTGCCTATATGCGTTTGAT
TAAGGGAGGAGGTGTGATTGATTTTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAACAGTTGGAAG
GCTTGGTTCAACAAGGATATCTCACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

65.176

100

0.652
  comYA Streptococcus mutans UA140

65.176

100

0.652
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.595

99.361

0.652
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.309

99.361

0.639
  comYA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.897

99.681

0.607
  comGA Lactococcus lactis subsp. cremoris KW2

51.447

99.361

0.511
  comGA Latilactobacillus sakei subsp. sakei 23K

41.697

86.581

0.361