Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   V6U69_RS00720 Genome accession   NZ_CP145867
Coordinates   132844..133944 (+) Length   366 a.a.
NCBI ID   WP_155115607.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS10     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 127844..138944
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U69_RS00710 (V6U69_00710) - 131579..131941 (+) 363 WP_002885749.1 DUF1033 family protein -
  V6U69_RS00715 (V6U69_00715) comYA 132021..132962 (+) 942 WP_002885658.1 competence type IV pilus ATPase ComGA Machinery gene
  V6U69_RS00720 (V6U69_00720) comYB 132844..133944 (+) 1101 WP_155115607.1 competence type IV pilus assembly protein ComGB Machinery gene
  V6U69_RS00725 (V6U69_00725) comYC 133953..134267 (+) 315 WP_037611125.1 competence type IV pilus major pilin ComGC Machinery gene
  V6U69_RS00730 (V6U69_00730) comYD 134227..134655 (+) 429 WP_260312930.1 competence type IV pilus minor pilin ComGD Machinery gene
  V6U69_RS00735 (V6U69_00735) comGE 134687..134917 (+) 231 WP_002887015.1 competence type IV pilus minor pilin ComGE -
  V6U69_RS00740 (V6U69_00740) comYF 134904..135341 (+) 438 WP_022496100.1 competence type IV pilus minor pilin ComGF Machinery gene
  V6U69_RS00745 (V6U69_00745) comGG 135319..135636 (+) 318 WP_021144683.1 competence type IV pilus minor pilin ComGG -
  V6U69_RS00750 (V6U69_00750) comYH 135681..136637 (+) 957 WP_410533909.1 class I SAM-dependent methyltransferase Machinery gene
  V6U69_RS00755 (V6U69_00755) - 136694..137887 (+) 1194 WP_410533911.1 acetate kinase -
  V6U69_RS00760 (V6U69_00760) - 138138..138335 (+) 198 WP_013991261.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41634.62 Da        Isoelectric Point: 10.0357

>NTDB_id=940756 V6U69_RS00720 WP_155115607.1 132844..133944(+) (comYB) [Streptococcus salivarius strain KSS10]
MPVKISKAIRQPAGTNSWKAWFNKDISLKGISKGKKLKINQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KASLMRGDRLDQMFASVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKDNWAVQLVQIFPQLFFVSLCGLLVLSLILYLWVKHQPALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGIDLLDLVSLMQEQKSKLFRELGADLEEGLMLGQSFPDRIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFVIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=940756 V6U69_RS00720 WP_155115607.1 132844..133944(+) (comYB) [Streptococcus salivarius strain KSS10]
TTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAACAGTTGGAAGGCTTGGTTCAACAAGGATATCTC
ACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAATCAGCAAGTCAAGGTTATCCAGCTTTTCAAACAACTTCTAA
AGGCAGGGTTTACTTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTGAAAGAATCGTCATTATCTCTTATG
AAAGCAAGCTTAATGCGAGGCGACAGGCTAGACCAGATGTTTGCGTCAGTGGGTTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAATCTTCTAGGGAGTTTAACCAAGATTGAAACCTACATGCTTCGTATGACCAAGGTTC
GTAAGAAACTCATGGAGGTAGCGACCTACCCTATCCTACTCCTGGGTTTCCTGATTCTGATTATGTTAGGACTTAAAAAT
TATCTTTTACCGCAACTGTTAGAGGGTGATGGTAAGGATAATTGGGCTGTACAGTTGGTTCAAATCTTTCCTCAGCTCTT
CTTTGTGAGTTTGTGTGGACTTCTTGTATTAAGCTTAATTCTTTATCTATGGGTCAAACACCAGCCAGCCCTTGTCTTTT
ATCGACGAATGGCAAAAATCCCTTTCATAGGCCAAACTGTCAGGCTATATACGACCGCCTATTATGCTAGGGAATGGGGA
AACCTCTTAGGACAAGGCATTGACCTGTTAGACTTGGTTTCTCTTATGCAAGAGCAAAAGTCCAAGCTATTTCGTGAGCT
GGGGGCTGATTTAGAAGAGGGCTTGATGCTAGGACAGAGTTTTCCTGACCGTATTGCTAGTCACCCTTTCTTCACTAAGG
AACTATCCTTAATTATTGCTTATGGAGAGGCTAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.81

93.716

0.514
  comYB Streptococcus mutans UA159

54.81

93.716

0.514
  comYB Streptococcus gordonii str. Challis substr. CH1

51.02

93.716

0.478
  comGB/cglB Streptococcus mitis NCTC 12261

49.568

94.809

0.47
  comGB/cglB Streptococcus mitis SK321

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae Rx1

49.112

92.35

0.454
  comGB/cglB Streptococcus pneumoniae D39

49.112

92.35

0.454
  comGB/cglB Streptococcus pneumoniae R6

49.112

92.35

0.454
  comGB/cglB Streptococcus pneumoniae TIGR4

49.112

92.35

0.454
  comGB Lactococcus lactis subsp. cremoris KW2

45.946

90.984

0.418