Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   V6T26_RS00695 Genome accession   NZ_CP145858
Coordinates   128134..129075 (+) Length   313 a.a.
NCBI ID   WP_410541295.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS11     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 123134..134075
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6T26_RS00685 (V6T26_00685) rpoC 123890..127528 (+) 3639 WP_037603707.1 DNA-directed RNA polymerase subunit beta' -
  V6T26_RS00690 (V6T26_00690) - 127691..128053 (+) 363 WP_002887019.1 DUF1033 family protein -
  V6T26_RS00695 (V6T26_00695) comYA 128134..129075 (+) 942 WP_410541295.1 competence type IV pilus ATPase ComGA Machinery gene
  V6T26_RS00700 (V6T26_00700) comYB 128957..130057 (+) 1101 WP_410531677.1 competence type IV pilus assembly protein ComGB Machinery gene
  V6T26_RS00705 (V6T26_00705) comYC 130054..130380 (+) 327 WP_410541296.1 competence type IV pilus major pilin ComGC Machinery gene
  V6T26_RS00710 (V6T26_00710) comYD 130340..130768 (+) 429 WP_253183867.1 competence type IV pilus minor pilin ComGD Machinery gene
  V6T26_RS00715 (V6T26_00715) comGE 130740..131030 (+) 291 WP_073689936.1 competence type IV pilus minor pilin ComGE -
  V6T26_RS00720 (V6T26_00720) comYF 131017..131454 (+) 438 WP_037600123.1 competence type IV pilus minor pilin ComGF Machinery gene
  V6T26_RS00725 (V6T26_00725) comGG 131432..131749 (+) 318 WP_155222523.1 competence type IV pilus minor pilin ComGG -
  V6T26_RS00730 (V6T26_00730) comYH 131794..132750 (+) 957 WP_155222522.1 class I SAM-dependent methyltransferase Machinery gene
  V6T26_RS00735 (V6T26_00735) - 132807..134000 (+) 1194 WP_003095894.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35285.29 Da        Isoelectric Point: 5.4456

>NTDB_id=940219 V6T26_RS00695 WP_410541295.1 128134..129075(+) (comYA) [Streptococcus salivarius strain KSS11]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGQRVSLRLSTVGDYRGLESLVIRVLHSERRDLVYWNQGIQLIMDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDNLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSVAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFASENFQSHSSTSWNQQLEGLVQQGYLTEGDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=940219 V6T26_RS00695 WP_410541295.1 128134..129075(+) (comYA) [Streptococcus salivarius strain KSS11]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTACGAGCTCTATATGCGAGTTGGCCAAGAGAGGAGATTAATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTAGGTTCCTGTGACTATGAT
TGTGGTGATGGTCAAAGGGTTTCTCTGCGTTTATCAACCGTTGGGGATTATCGCGGCTTAGAAAGTTTAGTTATTCGTGT
TCTACATTCCGAACGTCGAGACTTGGTGTATTGGAATCAAGGAATCCAGCTGATTATGGATGCTTTGGATTATCGTGGCT
TGTATCTCTTTGCAGGTCCCGTAGGTTCTGGAAAGACTACGCTTATGCATGAATTGGTTCAGGAGCGTTTTAAGGGACAG
CAGGTGATTTCGATTGAAGATCCTGTGGAAATTAAACAGGATAATGTCTTGCAACTCCAGGTAAATCAGGCAATTGACAT
GACCTATGATAATTTGATTAAGCTATCACTACGTCACCGTCCGGATGTTTTGATTATTGGAGAAATTCGAGATAAGGAGA
CTGCTCGAGCGGTTATTAGAGCTAGTCTGACAGGAGTGACTGTTCTTTCAACTATTCACGCAAAGAGTGTGGCAGGTGTT
TATGAGCGTCTTCTGGACCTCGGTGTAGATAAGTCTGAGTTGGATAATGCTCTTCAAGGGATTGCCTATATGCGTTTGAT
TAAGGGAGGAGGTGTGATTGATTTTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAACAGTTGGAAG
GCTTGGTTCAACAAGGATATCTCACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

65.815

100

0.658
  comYA Streptococcus mutans UA140

65.815

100

0.658
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.63

99.361

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.63

99.361

0.642
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.63

99.361

0.642
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.63

99.361

0.642
  comYA Streptococcus gordonii str. Challis substr. CH1

62.62

100

0.626
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.577

99.681

0.604
  comGA Lactococcus lactis subsp. cremoris KW2

51.125

99.361

0.508
  comGA Latilactobacillus sakei subsp. sakei 23K

41.392

87.22

0.361