Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   V6T26_RS00700 Genome accession   NZ_CP145858
Coordinates   128957..130057 (+) Length   366 a.a.
NCBI ID   WP_410531677.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS11     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 123957..135057
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6T26_RS00690 (V6T26_00690) - 127691..128053 (+) 363 WP_002887019.1 DUF1033 family protein -
  V6T26_RS00695 (V6T26_00695) comYA 128134..129075 (+) 942 WP_410541295.1 competence type IV pilus ATPase ComGA Machinery gene
  V6T26_RS00700 (V6T26_00700) comYB 128957..130057 (+) 1101 WP_410531677.1 competence type IV pilus assembly protein ComGB Machinery gene
  V6T26_RS00705 (V6T26_00705) comYC 130054..130380 (+) 327 WP_410541296.1 competence type IV pilus major pilin ComGC Machinery gene
  V6T26_RS00710 (V6T26_00710) comYD 130340..130768 (+) 429 WP_253183867.1 competence type IV pilus minor pilin ComGD Machinery gene
  V6T26_RS00715 (V6T26_00715) comGE 130740..131030 (+) 291 WP_073689936.1 competence type IV pilus minor pilin ComGE -
  V6T26_RS00720 (V6T26_00720) comYF 131017..131454 (+) 438 WP_037600123.1 competence type IV pilus minor pilin ComGF Machinery gene
  V6T26_RS00725 (V6T26_00725) comGG 131432..131749 (+) 318 WP_155222523.1 competence type IV pilus minor pilin ComGG -
  V6T26_RS00730 (V6T26_00730) comYH 131794..132750 (+) 957 WP_155222522.1 class I SAM-dependent methyltransferase Machinery gene
  V6T26_RS00735 (V6T26_00735) - 132807..134000 (+) 1194 WP_003095894.1 acetate kinase -
  V6T26_RS00740 (V6T26_00740) - 134251..134448 (+) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41662.68 Da        Isoelectric Point: 10.0357

>NTDB_id=940220 V6T26_RS00700 WP_410531677.1 128957..130057(+) (comYB) [Streptococcus salivarius strain KSS11]
MPVKISKAIRQPAGTNSWKAWFNKDISLKGISKGKKLKINQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KASLMRGDRLDQMFASVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKDNWAVQLVQIFPQLFFVSLCGLLVLSLILYLWVKHQPALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGIDLLDLVSLMQEQKSKLFRELGADLEEALMLGQSFPDRIATHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFVIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=940220 V6T26_RS00700 WP_410531677.1 128957..130057(+) (comYB) [Streptococcus salivarius strain KSS11]
TTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAACAGTTGGAAGGCTTGGTTCAACAAGGATATCTC
ACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAATCAGCAAGTCAAGGTTATCCAGCTTTTCAAACAACTTCTAA
AGGCAGGGTTTACTTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCATTTGTTGAAAGAATCGTCATTATCTCTTATG
AAAGCAAGCTTAATGCGAGGCGACAGGCTAGACCAGATGTTTGCATCAGTGGGTTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAATCTTCTAGGGAGTTTAACCAAGATTGAAACCTACATGCTTCGCATGACCAAGGTTC
GTAAGAAACTCATGGAGGTAGCGACCTACCCTATTCTACTCCTGGGTTTCCTGATTCTGATTATGTTAGGACTTAAAAAT
TATCTTTTACCTCAACTGTTAGAGGGTGATGGTAAGGATAATTGGGCTGTACAGTTGGTTCAAATCTTTCCCCAGCTCTT
CTTTGTGAGTTTGTGTGGACTTCTTGTATTAAGCTTAATTCTTTATCTATGGGTCAAACACCAGCCAGCTCTTGTCTTTT
ATCGACGAATGGCAAAAATCCCTTTCATAGGCCAAACTGTCAGGCTATATACGACCGCCTATTATGCTAGGGAATGGGGA
AATCTCTTAGGACAAGGCATTGACCTGTTAGACTTGGTTTCTCTTATGCAAGAGCAAAAGTCCAAGCTCTTTCGTGAGCT
GGGGGCTGATTTAGAAGAGGCCTTGATGCTAGGACAGAGTTTTCCTGACCGAATTGCTACTCACCCATTTTTCACTAAGG
AGCTATCCTTAATTATTGCTTATGGAGAGGCCAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

55.102

93.716

0.516
  comYB Streptococcus mutans UA159

55.102

93.716

0.516
  comYB Streptococcus gordonii str. Challis substr. CH1

51.02

93.716

0.478
  comGB/cglB Streptococcus mitis NCTC 12261

50.144

94.809

0.475
  comGB/cglB Streptococcus mitis SK321

49.704

92.35

0.459
  comGB/cglB Streptococcus pneumoniae Rx1

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae D39

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae R6

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae TIGR4

49.408

92.35

0.456
  comGB Lactococcus lactis subsp. cremoris KW2

45.646

90.984

0.415