Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   V6T26_RS00730 Genome accession   NZ_CP145858
Coordinates   131794..132750 (+) Length   318 a.a.
NCBI ID   WP_155222522.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS11     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 126794..137750
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6T26_RS00690 (V6T26_00690) - 127691..128053 (+) 363 WP_002887019.1 DUF1033 family protein -
  V6T26_RS00695 (V6T26_00695) comYA 128134..129075 (+) 942 WP_410541295.1 competence type IV pilus ATPase ComGA Machinery gene
  V6T26_RS00700 (V6T26_00700) comYB 128957..130057 (+) 1101 WP_410531677.1 competence type IV pilus assembly protein ComGB Machinery gene
  V6T26_RS00705 (V6T26_00705) comYC 130054..130380 (+) 327 WP_410541296.1 competence type IV pilus major pilin ComGC Machinery gene
  V6T26_RS00710 (V6T26_00710) comYD 130340..130768 (+) 429 WP_253183867.1 competence type IV pilus minor pilin ComGD Machinery gene
  V6T26_RS00715 (V6T26_00715) comGE 130740..131030 (+) 291 WP_073689936.1 competence type IV pilus minor pilin ComGE -
  V6T26_RS00720 (V6T26_00720) comYF 131017..131454 (+) 438 WP_037600123.1 competence type IV pilus minor pilin ComGF Machinery gene
  V6T26_RS00725 (V6T26_00725) comGG 131432..131749 (+) 318 WP_155222523.1 competence type IV pilus minor pilin ComGG -
  V6T26_RS00730 (V6T26_00730) comYH 131794..132750 (+) 957 WP_155222522.1 class I SAM-dependent methyltransferase Machinery gene
  V6T26_RS00735 (V6T26_00735) - 132807..134000 (+) 1194 WP_003095894.1 acetate kinase -
  V6T26_RS00740 (V6T26_00740) - 134251..134448 (+) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  V6T26_RS00745 (V6T26_00745) - 134460..135116 (+) 657 WP_410541297.1 CPBP family intramembrane glutamic endopeptidase -
  V6T26_RS00750 (V6T26_00750) - 135194..135640 (+) 447 WP_013991259.1 hypothetical protein -
  V6T26_RS00755 (V6T26_00755) - 135753..136415 (+) 663 WP_013991258.1 CPBP family intramembrane glutamic endopeptidase -
  V6T26_RS00760 (V6T26_00760) proC 136442..137212 (-) 771 WP_013991257.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 35789.69 Da        Isoelectric Point: 4.3482

>NTDB_id=940224 V6T26_RS00730 WP_155222522.1 131794..132750(+) (comYH) [Streptococcus salivarius strain KSS11]
MNFEAIETAFELLLENVQTIENDLGTHAYDALIEQNSYYLGAEVANEVIIKNNEKLRALDLSKEEWRRAFQFLFIKLGQL
EALQANHQFTPDAIGFIILYLLEGLTKDDQLDILEIGSGTGNLAETLLNNSQKTLNYMGMEVDDLLIDLSASIADVVNSS
AVYIQEDAVRPHILKESDVIISDLPVGYYPNDEIASRFKVAATGEHTYAHHLLMEQSLKYLKKDGIAILLAPTNLLTSPQ
SDLLKKWLSGYADIIAVITLPEAAFGNKHNMKSIFVLKKQTENAPETFVYPLSDLQNPEILKDFTENFQKWKSDNSIF

Nucleotide


Download         Length: 957 bp        

>NTDB_id=940224 V6T26_RS00730 WP_155222522.1 131794..132750(+) (comYH) [Streptococcus salivarius strain KSS11]
ATGAATTTTGAAGCAATTGAGACAGCTTTTGAGCTGTTGTTAGAAAATGTCCAAACCATTGAAAATGATCTTGGAACCCA
TGCTTACGATGCACTTATTGAGCAAAATTCCTATTATTTGGGGGCTGAGGTAGCTAATGAAGTCATCATCAAAAACAACG
AGAAATTACGTGCTCTTGATCTAAGTAAAGAGGAGTGGCGTCGTGCTTTTCAGTTCTTGTTTATCAAACTAGGGCAATTG
GAAGCTTTACAAGCCAATCACCAATTTACACCAGATGCTATTGGATTTATCATTCTTTACCTACTCGAAGGTTTGACCAA
GGACGACCAATTAGATATTTTAGAGATTGGTTCAGGGACAGGAAACTTAGCTGAAACCCTTCTAAATAATAGTCAGAAAA
CCCTTAATTATATGGGAATGGAAGTTGACGATCTCCTTATCGATTTGTCAGCTAGTATTGCTGATGTGGTAAATTCAAGT
GCAGTTTATATCCAAGAAGATGCTGTTCGACCACACATTCTCAAAGAGAGTGATGTTATTATCAGTGACCTACCTGTTGG
GTATTACCCAAATGATGAGATTGCGAGTCGTTTCAAGGTTGCAGCAACTGGTGAACACACCTATGCCCATCACCTTCTCA
TGGAGCAATCACTCAAGTACCTGAAGAAAGATGGTATTGCTATTCTTTTGGCACCAACTAATCTTTTGACAAGCCCACAA
AGTGACTTGCTTAAGAAATGGCTATCAGGATATGCTGATATTATTGCCGTTATCACTCTTCCAGAAGCAGCTTTTGGCAA
TAAACATAATATGAAGTCTATCTTCGTGCTTAAAAAACAAACTGAAAATGCTCCAGAGACCTTTGTTTATCCACTTAGCG
ATTTGCAAAACCCAGAGATCCTCAAGGATTTCACAGAGAATTTCCAAAAATGGAAATCAGATAATTCCATTTTCTAG

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

70.159

99.057

0.695
  comYH Streptococcus mutans UA140

70.159

99.057

0.695