Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC   Type   Machinery gene
Locus tag   VP459_RS13460 Genome accession   NZ_CP142600
Coordinates   2749380..2749691 (+) Length   103 a.a.
NCBI ID   WP_000472256.1    Uniprot ID   -
Organism   Staphylococcus aureus strain M19060305     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 2744380..2754691
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VP459_RS13430 (VP459_13435) - 2745163..2745366 (+) 204 WP_000087561.1 YqgQ family protein -
  VP459_RS13435 (VP459_13440) - 2745363..2746349 (+) 987 WP_000161315.1 ROK family glucokinase -
  VP459_RS13440 (VP459_13445) - 2746349..2746678 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  VP459_RS13445 (VP459_13450) - 2746675..2747298 (+) 624 WP_001223006.1 MBL fold metallo-hydrolase -
  VP459_RS13450 (VP459_13455) comGA 2747350..2748324 (+) 975 WP_000697215.1 competence type IV pilus ATPase ComGA Machinery gene
  VP459_RS13455 (VP459_13460) comGB 2748296..2749366 (+) 1071 WP_000776403.1 competence type IV pilus assembly protein ComGB Machinery gene
  VP459_RS13460 (VP459_13465) comGC 2749380..2749691 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  VP459_RS13465 (VP459_13470) comGD 2749669..2750115 (+) 447 WP_075583651.1 competence type IV pilus minor pilin ComGD Machinery gene
  VP459_RS13470 (VP459_13475) comGE 2750102..2750401 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  VP459_RS13475 (VP459_13480) comGF 2750319..2750816 (+) 498 WP_029697681.1 competence type IV pilus minor pilin ComGF Machinery gene
  VP459_RS13480 (VP459_13485) - 2750913..2751059 (+) 147 WP_001789879.1 hypothetical protein -
  VP459_RS13485 (VP459_13490) - 2751049..2751573 (+) 525 WP_001015122.1 shikimate kinase -
  VP459_RS13490 (VP459_13495) gcvT 2751732..2752823 (+) 1092 WP_000093355.1 glycine cleavage system aminomethyltransferase GcvT -
  VP459_RS13495 (VP459_13500) gcvPA 2752843..2754189 (+) 1347 WP_000019688.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence


Protein


Download         Length: 103 a.a.        Molecular weight: 11315.36 Da        Isoelectric Point: 8.5268

>NTDB_id=926164 VP459_RS13460 WP_000472256.1 2749380..2749691(+) (comGC) [Staphylococcus aureus strain M19060305]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEAQKTCKSGETITISNGEAVAN

Nucleotide


Download         Length: 312 bp        

>NTDB_id=926164 VP459_RS13460 WP_000472256.1 2749380..2749691(+) (comGC) [Staphylococcus aureus strain M19060305]
ATGTTTAAATTTCTTAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGCACAAAAGACATGTAAATCAGGAGAGACAATCACAATTAGTAATGGAGAAGCAGTTGCAAATTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Staphylococcus aureus MW2

100

100

1

  comGC Staphylococcus aureus N315

100

100

1

  comGC/cglC Streptococcus pneumoniae TIGR4

46.078

99.029

0.456

  comGC/cglC Streptococcus pneumoniae Rx1

46.078

99.029

0.456

  comGC/cglC Streptococcus pneumoniae D39

46.078

99.029

0.456

  comGC/cglC Streptococcus pneumoniae R6

46.078

99.029

0.456

  comGC/cglC Streptococcus mitis SK321

51.163

83.495

0.427

  comGC/cglC Streptococcus mitis NCTC 12261

51.163

83.495

0.427

  comYC Streptococcus gordonii str. Challis substr. CH1

42.857

95.146

0.408

  comYC Streptococcus suis isolate S10

50

75.728

0.379

  comGC Bacillus subtilis subsp. subtilis str. 168

41.758

88.35

0.369

  comGC Lactococcus lactis subsp. cremoris KW2

46.341

79.612

0.369