Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   VKP53_RS00785 Genome accession   NZ_CP142354
Coordinates   118811..119137 (+) Length   108 a.a.
NCBI ID   WP_002986552.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 6745-99     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 113811..124137
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP53_RS00770 (VKP53_00770) - 116458..116823 (+) 366 WP_002986560.1 DUF1033 family protein -
  VKP53_RS00775 (VKP53_00775) comYA 116916..117839 (+) 924 WP_136281985.1 competence type IV pilus ATPase ComGA Machinery gene
  VKP53_RS00780 (VKP53_00780) comYB 117775..118809 (+) 1035 WP_231871599.1 competence type IV pilus assembly protein ComGB Machinery gene
  VKP53_RS00785 (VKP53_00785) comYC 118811..119137 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  VKP53_RS00790 (VKP53_00790) comGD 119112..119540 (+) 429 WP_023605232.1 competence type IV pilus minor pilin ComGD -
  VKP53_RS00795 (VKP53_00795) comGE 119497..119781 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  VKP53_RS00800 (VKP53_00800) comYF 119774..120208 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  VKP53_RS00805 (VKP53_00805) comGG 120192..120518 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  VKP53_RS00810 (VKP53_00810) comYH 120616..121569 (+) 954 WP_326674822.1 class I SAM-dependent methyltransferase Machinery gene
  VKP53_RS00815 (VKP53_00815) - 121628..122824 (+) 1197 WP_030126459.1 acetate kinase -
  VKP53_RS00820 (VKP53_00820) - 123010..123318 (+) 309 Protein_115 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12376.36 Da        Isoelectric Point: 9.8992

>NTDB_id=925194 VKP53_RS00785 WP_002986552.1 118811..119137(+) (comYC) [Streptococcus pyogenes strain 6745-99]
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=925194 VKP53_RS00785 WP_002986552.1 118811..119137(+) (comYC) [Streptococcus pyogenes strain 6745-99]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546
  comGC Lactococcus lactis subsp. cremoris KW2

56.863

94.444

0.537
  comGC/cglC Streptococcus mitis SK321

61.957

85.185

0.528
  comGC/cglC Streptococcus pneumoniae R6

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae TIGR4

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae D39

60.87

85.185

0.519
  comGC/cglC Streptococcus mitis NCTC 12261

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae Rx1

60.87

85.185

0.519
  comYC Streptococcus mutans UA140

55.208

88.889

0.491
  comYC Streptococcus mutans UA159

55.208

88.889

0.491
  comYC Streptococcus suis isolate S10

59.259

75

0.444