Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | VKP53_RS00810 | Genome accession | NZ_CP142354 |
| Coordinates | 120616..121569 (+) | Length | 317 a.a. |
| NCBI ID | WP_326674822.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain 6745-99 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 115616..126569
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| VKP53_RS00770 (VKP53_00770) | - | 116458..116823 (+) | 366 | WP_002986560.1 | DUF1033 family protein | - |
| VKP53_RS00775 (VKP53_00775) | comYA | 116916..117839 (+) | 924 | WP_136281985.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| VKP53_RS00780 (VKP53_00780) | comYB | 117775..118809 (+) | 1035 | WP_231871599.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| VKP53_RS00785 (VKP53_00785) | comYC | 118811..119137 (+) | 327 | WP_002986552.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| VKP53_RS00790 (VKP53_00790) | comGD | 119112..119540 (+) | 429 | WP_023605232.1 | competence type IV pilus minor pilin ComGD | - |
| VKP53_RS00795 (VKP53_00795) | comGE | 119497..119781 (+) | 285 | WP_002987779.1 | competence type IV pilus minor pilin ComGE | - |
| VKP53_RS00800 (VKP53_00800) | comYF | 119774..120208 (+) | 435 | WP_002992738.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| VKP53_RS00805 (VKP53_00805) | comGG | 120192..120518 (+) | 327 | WP_010921801.1 | competence type IV pilus minor pilin ComGG | - |
| VKP53_RS00810 (VKP53_00810) | comYH | 120616..121569 (+) | 954 | WP_326674822.1 | class I SAM-dependent methyltransferase | Machinery gene |
| VKP53_RS00815 (VKP53_00815) | - | 121628..122824 (+) | 1197 | WP_030126459.1 | acetate kinase | - |
| VKP53_RS00820 (VKP53_00820) | - | 123010..123318 (+) | 309 | Protein_115 | hypothetical protein | - |
| VKP53_RS00825 (VKP53_00825) | proC | 123401..124171 (-) | 771 | WP_002986527.1 | pyrroline-5-carboxylate reductase | - |
| VKP53_RS00830 (VKP53_00830) | pepA | 124219..125286 (-) | 1068 | WP_002987798.1 | glutamyl aminopeptidase | - |
| VKP53_RS00835 (VKP53_00835) | - | 125751..126035 (+) | 285 | WP_129321436.1 | DUF4651 domain-containing protein | - |
| VKP53_RS00840 (VKP53_00840) | - | 126032..126349 (+) | 318 | WP_002986515.1 | thioredoxin family protein | - |
Sequence
Protein
Download Length: 317 a.a. Molecular weight: 36088.22 Da Isoelectric Point: 4.7956
>NTDB_id=925196 VKP53_RS00810 WP_326674822.1 120616..121569(+) (comYH) [Streptococcus pyogenes strain 6745-99]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVTLIMLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKRAENIHDFMENFKKWKLSNVN
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVTLIMLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKRAENIHDFMENFKKWKLSNVN
Nucleotide
Download Length: 954 bp
>NTDB_id=925196 VKP53_RS00810 WP_326674822.1 120616..121569(+) (comYH) [Streptococcus pyogenes strain 6745-99]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCACTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTAGTGACCTTGATTATGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCGTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCACTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTAGTGACCTTGATTATGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCGTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
65.823 |
99.685 |
0.656 |
| comYH | Streptococcus mutans UA140 |
65.506 |
99.685 |
0.653 |