Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   SM123_RS09980 Genome accession   NZ_CP139419
Coordinates   2060381..2061322 (-) Length   313 a.a.
NCBI ID   WP_320909535.1    Uniprot ID   -
Organism   Streptococcus lingualis strain S5     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2055381..2066322
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM123_RS09945 (SM123_09945) comYH 2056606..2057559 (-) 954 WP_049505971.1 class I SAM-dependent methyltransferase Machinery gene
  SM123_RS09950 (SM123_09950) comGG 2057590..2058057 (-) 468 WP_320909534.1 competence type IV pilus minor pilin ComGG -
  SM123_RS09955 (SM123_09955) comGF/cglF 2058014..2058466 (-) 453 WP_151190960.1 competence type IV pilus minor pilin ComGF Machinery gene
  SM123_RS09960 (SM123_09960) comGE 2058456..2058743 (-) 288 WP_151190959.1 competence type IV pilus minor pilin ComGE -
  SM123_RS09965 (SM123_09965) comYD 2058709..2059113 (-) 405 WP_269796580.1 competence type IV pilus minor pilin ComGD Machinery gene
  SM123_RS09970 (SM123_09970) comYC 2059103..2059420 (-) 318 WP_101770912.1 competence type IV pilus major pilin ComGC Machinery gene
  SM123_RS09975 (SM123_09975) comYB 2059417..2060448 (-) 1032 WP_320910010.1 competence type IV pilus assembly protein ComGB Machinery gene
  SM123_RS09980 (SM123_09980) comYA 2060381..2061322 (-) 942 WP_320909535.1 competence type IV pilus ATPase ComGA Machinery gene
  SM123_RS09985 (SM123_09985) - 2061410..2061799 (-) 390 WP_037608454.1 DUF1033 family protein -
  SM123_RS09990 (SM123_09990) - 2062020..2063123 (-) 1104 WP_049475202.1 glycosyl hydrolase family 8 -
  SM123_RS09995 (SM123_09995) - 2063132..2064442 (-) 1311 WP_049472878.1 glycosyltransferase -
  SM123_RS10000 (SM123_10000) - 2064435..2064575 (-) 141 WP_003009749.1 hypothetical protein -
  SM123_RS10005 (SM123_10005) - 2064585..2065373 (-) 789 WP_023919656.1 hypothetical protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35842.22 Da        Isoelectric Point: 6.7634

>NTDB_id=909571 SM123_RS09980 WP_320909535.1 2060381..2061322(-) (comYA) [Streptococcus lingualis strain S5]
MVQEIAKKLIRMGKKEEAQDLYFIPRKEEYQVSMRVGDERRFVQSFPFEEMTAMISHFKFVAGMNVGEKRRSQLGSCDYP
LENGVVSIRLSTVGDYRGYESLVIRLLHDEERELRFWFDQLPDLKKKLAGRGLYLFAGPVGSGKTTLMHALAQERFADQQ
VMSIEDPVEIKQDNMLQLQLNDQIGMTYDNLIKLSLRHRPDLLIIGEIRDKETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVSEEELKIVLQGICYQRLIAGGGVVDFATENYQEHSASRWNQQMDLLAQSGYIQLAQAQAEKIIYR

Nucleotide


Download         Length: 942 bp        

>NTDB_id=909571 SM123_RS09980 WP_320909535.1 2060381..2061322(-) (comYA) [Streptococcus lingualis strain S5]
ATGGTTCAAGAAATTGCAAAAAAACTGATCCGTATGGGGAAAAAGGAAGAAGCTCAGGATCTTTACTTCATTCCTCGGAA
GGAGGAGTACCAAGTTTCTATGAGGGTGGGAGACGAGAGGCGCTTTGTGCAGTCCTTCCCTTTTGAGGAGATGACAGCTA
TGATTAGCCACTTTAAGTTCGTAGCAGGGATGAATGTGGGAGAAAAAAGGCGCAGCCAGCTAGGATCGTGTGATTACCCT
TTGGAGAATGGAGTGGTCTCGATTCGCTTGTCGACGGTGGGGGATTATCGTGGTTATGAAAGCTTGGTCATTCGGCTCTT
GCATGATGAGGAACGTGAATTGCGGTTTTGGTTTGATCAGTTGCCGGACTTGAAGAAGAAATTGGCTGGTCGTGGGCTTT
ATCTTTTTGCGGGCCCCGTTGGCTCGGGAAAGACCACTCTCATGCATGCTTTAGCGCAAGAGCGCTTTGCGGACCAGCAA
GTCATGTCTATTGAAGACCCTGTCGAGATCAAGCAGGATAATATGCTTCAGCTTCAGCTGAATGACCAGATTGGCATGAC
CTATGACAACCTGATCAAACTCTCCTTACGCCATCGGCCGGACCTTCTCATCATTGGAGAGATCCGAGATAAGGAAACAG
CTCGTGCAGTCGTACGAGCTAGTTTAACAGGAGTCACCGTCTTCTCTACGATTCATGCCAAGAGCGTTCGAGGTGTTTAT
GAGAGGCTCTTAGAACTTGGAGTGAGTGAGGAAGAGCTCAAGATTGTTTTACAAGGTATTTGCTACCAACGATTAATTGC
AGGAGGAGGTGTGGTCGATTTTGCGACGGAAAACTACCAAGAGCACTCAGCCAGCCGCTGGAACCAACAAATGGATCTCT
TGGCTCAATCGGGATATATCCAGCTGGCTCAGGCCCAAGCCGAAAAAATTATCTACCGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(15-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

73.548

99.042

0.728
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

71.795

99.681

0.716
  comGA/cglA/cilD Streptococcus pneumoniae D39

71.474

99.681

0.712
  comGA/cglA/cilD Streptococcus pneumoniae R6

71.474

99.681

0.712
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

71.474

99.681

0.712
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

71.474

99.681

0.712
  comYA Streptococcus mutans UA159

64.952

99.361

0.645
  comYA Streptococcus mutans UA140

64.952

99.361

0.645
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.258

99.042

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

99.681

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

42.086

88.818

0.374