Detailed information NTG0892715

Bioinformatically predicted

Overview

• Name: comE
• Type: Regulator
• Locus tag: RYQ61_RS04055
• Genome accession: NZ_CP136799
• Coordinates: 769470..770219 (-)
• Length: 249 a.a.
• NCBI ID: WP_048784767.1
• Uniprot ID: -
• Organism: Streptococcus intermedius strain XH2169
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 764470..775219

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RYQ61_RS04035 (RYQ61_04035)	-	764874..766496 (+)	1623	WP_102568366.1	ATP-binding cassette domain-containing protein	-
RYQ61_RS04040 (RYQ61_04040)	-	766570..769146 (+)	2577	WP_102568365.1	YfhO family protein	-
RYQ61_RS04055 (RYQ61_04055)	comE	769470..770219 (-)	750	WP_048784767.1	competence system response regulator transcription factor ComE	Regulator
RYQ61_RS04060 (RYQ61_04060)	comD/comD1	770219..771544 (-)	1326	WP_003075490.1	GHKL domain-containing protein	Regulator
RYQ61_RS04065 (RYQ61_04065)	-	771561..771707 (-)	147	WP_003075491.1	bacteriocin	-
RYQ61_RS04075 (RYQ61_04075)	rlmH	771984..772463 (-)	480	WP_003075603.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
RYQ61_RS04080 (RYQ61_04080)	htrA	772667..773866 (+)	1200	WP_317289752.1	trypsin-like peptidase domain-containing protein	Regulator
RYQ61_RS04085 (RYQ61_04085)	spo0J	773921..774688 (+)	768	WP_003075591.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 29189.74 Da
• Isoelectric Point: 8.0443

>NTDB_id=892715 RYQ61_RS04055 WP_048784767.1 769470..770219(-) (comE) [Streptococcus intermedius strain XH2169]
MKVLVLEDEISHQVRMETTLAEIAKEMGISIKVKVTGKIREFKEYIENDEVNQLYFLDIDIKGEETKGLEIAKFIRHHNP
YAIIVFVTTKSEFATMTFKYKVSALDFVDKNLNDVAFKKHIKDSIEYTKATLIENKDMVDYFEYSFRGGEVRMPFNDILY
IETTGSSHKLRIVGKNFFKEFYGTIADIQEKDKETQRFFSPHKSYLVNIGNIKSYDKKLKEIIFYEDHRCPITRMKIGKL
KTILEESKG

Nucleotide

• Length: 750 bp

>NTDB_id=892715 RYQ61_RS04055 WP_048784767.1 769470..770219(-) (comE) [Streptococcus intermedius strain XH2169]
ATGAAAGTATTAGTATTAGAAGATGAAATTTCACATCAAGTAAGAATGGAAACAACCTTGGCAGAGATTGCAAAAGAGAT
GGGAATTTCTATCAAAGTTAAAGTAACTGGAAAAATAAGAGAATTTAAAGAATATATTGAGAATGATGAAGTAAATCAAT
TATACTTTTTAGATATTGATATTAAAGGGGAAGAGACAAAAGGTTTAGAAATAGCAAAATTTATACGTCATCATAATCCG
TATGCTATTATTGTTTTTGTTACAACGAAATCAGAATTTGCTACTATGACTTTTAAATATAAAGTTTCTGCACTAGATTT
TGTTGATAAAAATTTGAATGATGTTGCTTTTAAAAAACATATAAAAGATAGTATCGAGTATACAAAAGCAACGTTGATTG
AAAATAAAGATATGGTTGATTATTTTGAATATAGTTTTCGTGGTGGAGAAGTTAGAATGCCATTTAATGATATTTTATAT
ATTGAAACGACAGGTTCTTCTCATAAATTAAGAATTGTAGGTAAAAACTTTTTTAAAGAATTTTATGGTACTATTGCAGA
TATTCAAGAAAAAGACAAGGAGACACAGCGTTTCTTTTCACCTCATAAATCTTATTTAGTTAATATTGGAAATATTAAGA
GTTATGACAAAAAACTGAAAGAAATTATTTTTTATGAAGATCACCGTTGCCCAATTACTCGAATGAAAATTGGAAAGTTG
AAAACTATTTTAGAGGAGTCAAAAGGGTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-121)

• LytTr DNA-binding domain (LytTR) (152-244)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Streptococcus mitis NCTC 12261	71.02	98.394	0.699
comE/comE2	Streptococcus gordonii strain NCTC7865	71.311	97.992	0.699
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	71.311	97.992	0.699
comE	Streptococcus infantis strain Atu-4	70.612	98.394	0.695
comE	Streptococcus mitis SK321	70.204	98.394	0.691
comE	Streptococcus pneumoniae Rx1	69.796	98.394	0.687
comE	Streptococcus pneumoniae D39	69.796	98.394	0.687
comE	Streptococcus pneumoniae R6	69.796	98.394	0.687
comE	Streptococcus pneumoniae TIGR4	69.796	98.394	0.687
comE/blpR	Streptococcus mutans UA159	40.161	100	0.402
comE/comE2	Streptococcus equinus JB1	35.019	100	0.361