Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   RYQ61_RS04080 Genome accession   NZ_CP136799
Coordinates   772667..773866 (+) Length   399 a.a.
NCBI ID   WP_317289752.1    Uniprot ID   -
Organism   Streptococcus intermedius strain XH2169     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 767667..778866
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RYQ61_RS04055 (RYQ61_04055) comE 769470..770219 (-) 750 WP_048784767.1 competence system response regulator transcription factor ComE Regulator
  RYQ61_RS04060 (RYQ61_04060) comD/comD1 770219..771544 (-) 1326 WP_003075490.1 GHKL domain-containing protein Regulator
  RYQ61_RS04065 (RYQ61_04065) - 771561..771707 (-) 147 WP_003075491.1 bacteriocin -
  RYQ61_RS04075 (RYQ61_04075) rlmH 771984..772463 (-) 480 WP_003075603.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  RYQ61_RS04080 (RYQ61_04080) htrA 772667..773866 (+) 1200 WP_317289752.1 trypsin-like peptidase domain-containing protein Regulator
  RYQ61_RS04085 (RYQ61_04085) spo0J 773921..774688 (+) 768 WP_003075591.1 ParB/RepB/Spo0J family partition protein Regulator
  RYQ61_RS04090 (RYQ61_04090) dnaA 774914..776257 (+) 1344 WP_048784762.1 chromosomal replication initiator protein DnaA -
  RYQ61_RS04095 (RYQ61_04095) dnaN 776413..777549 (+) 1137 WP_048784760.1 DNA polymerase III subunit beta -
  RYQ61_RS04100 (RYQ61_04100) - 777549..777746 (+) 198 WP_003075608.1 DUF951 domain-containing protein -
  RYQ61_RS04105 (RYQ61_04105) - 777769..778269 (-) 501 WP_021002257.1 DUF1307 domain-containing protein -

Sequence

Protein


Download         Length: 399 a.a.        Molecular weight: 42147.34 Da        Isoelectric Point: 10.1393

>NTDB_id=892717 RYQ61_RS04080 WP_317289752.1 772667..773866(+) (htrA) [Streptococcus intermedius strain XH2169]
MKNSSNFTKKFLWLFMVLTIGFIGGLLGLLGNVTSSKLNKNNTTTTKVNHVTTSYKNTNSTTQAVNKVKDAVVSVITYAN
NKSQNSIFGNDDFNSNNNNSQRVASEGSGVIYKKDSKYAYLVTNTHVINGASKVDIRLADGNKVPGEIVGSDTYSDISVV
RISASKVKSVAEFGDSSKLTVGETAIAIGSPLGSNYANTVTQGIISSLNRNVSLKSEDGQTISTQAIQTDTAINPGNSGG
PLVNIQGQVIGITSSKIASNRGTSVEGLGFAIPSNDVTNIISQLESNGAVTRPALGIQMIDISNLSSSDLSRLKLPAKVT
AGVVVRSAQSGMPAAGKLQKYDVITKIDGKDISSANDLQSALYKHSIGDDIKITFYRNGKETTTTIKLTKSTKDLNSNN

Nucleotide


Download         Length: 1200 bp        

>NTDB_id=892717 RYQ61_RS04080 WP_317289752.1 772667..773866(+) (htrA) [Streptococcus intermedius strain XH2169]
ATGAAAAACTCTTCAAATTTCACAAAAAAATTCTTATGGCTTTTCATGGTCTTAACTATAGGTTTTATTGGTGGTTTATT
AGGTTTATTAGGAAATGTAACTTCTTCAAAATTAAATAAAAACAACACAACTACTACTAAGGTTAACCATGTTACTACAT
CTTATAAAAATACCAATTCTACAACACAGGCTGTCAATAAAGTAAAGGATGCTGTTGTTTCTGTTATTACCTATGCTAAT
AATAAATCTCAAAATAGCATTTTTGGAAATGATGACTTTAATAGTAACAATAATAACTCACAAAGAGTAGCAAGCGAAGG
TTCAGGGGTTATTTATAAAAAAGACAGTAAGTATGCCTATCTTGTAACTAATACTCATGTTATTAATGGTGCTAGTAAAG
TGGATATTCGTTTAGCGGATGGTAACAAAGTTCCAGGAGAAATCGTAGGCTCAGATACTTACTCAGATATTTCTGTCGTC
CGTATTAGTGCGAGTAAAGTCAAGTCAGTTGCTGAATTTGGTGATTCTAGTAAATTAACTGTTGGAGAAACTGCTATTGC
TATTGGTAGCCCACTTGGATCAAATTATGCAAATACTGTTACTCAAGGAATTATTTCTAGCTTAAATCGTAATGTGTCTT
TAAAATCTGAAGATGGTCAAACTATCTCTACTCAAGCTATTCAAACAGATACAGCGATTAATCCTGGGAATTCTGGTGGT
CCACTTGTAAATATCCAAGGGCAAGTTATTGGTATTACTTCAAGTAAAATTGCTAGTAATCGTGGAACATCTGTAGAGGG
ATTAGGTTTTGCTATTCCATCTAATGATGTCACCAACATCATCAGTCAATTGGAATCAAACGGAGCAGTTACGCGACCAG
CTTTAGGAATTCAAATGATTGATATTAGTAATCTATCTAGTTCTGATTTATCACGTTTGAAACTTCCAGCAAAAGTGACT
GCAGGAGTTGTTGTTCGTTCAGCTCAGTCTGGAATGCCTGCAGCAGGAAAACTTCAAAAATATGATGTTATTACAAAGAT
AGATGGAAAAGACATTTCCTCAGCAAATGATTTACAATCTGCTTTATACAAACATTCAATTGGTGATGATATAAAAATTA
CATTTTATCGTAATGGAAAAGAAACAACCACCACCATTAAACTTACAAAATCTACAAAAGATTTAAATTCAAATAATTGA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(107-252)

PDZ domain (PDZ_2)

(293-388)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

74.69

100

0.754
  htrA Streptococcus mitis NCTC 12261

71

100

0.712
  htrA Streptococcus pneumoniae Rx1

70.781

99.499

0.704
  htrA Streptococcus pneumoniae D39

70.781

99.499

0.704
  htrA Streptococcus pneumoniae R6

70.781

99.499

0.704
  htrA Streptococcus pneumoniae TIGR4

70.781

99.499

0.704
  htrA Streptococcus mutans UA159

56.219

100

0.566