Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   RRU92_RS03435 Genome accession   NZ_CP135436
Coordinates   672057..672380 (+) Length   107 a.a.
NCBI ID   WP_315640431.1    Uniprot ID   A0AA96MP07
Organism   Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 667057..677380
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RRU92_RS03410 (RRU92_03410) nagA 667234..668385 (+) 1152 WP_315640424.1 N-acetylglucosamine-6-phosphate deacetylase -
  RRU92_RS03415 (RRU92_03415) - 668524..669582 (+) 1059 WP_315640425.1 zinc-dependent alcohol dehydrogenase family protein -
  RRU92_RS03420 (RRU92_03420) - 669720..670097 (+) 378 WP_315640427.1 DUF1033 family protein -
  RRU92_RS03425 (RRU92_03425) comGA/cglA/cilD 670151..671092 (+) 942 WP_070676995.1 competence type IV pilus ATPase ComGA Machinery gene
  RRU92_RS03430 (RRU92_03430) comGB/cglB 671013..672056 (+) 1044 WP_315640429.1 competence type IV pilus assembly protein ComGB Machinery gene
  RRU92_RS03435 (RRU92_03435) comGC/cglC 672057..672380 (+) 324 WP_315640431.1 competence type IV pilus major pilin ComGC Machinery gene
  RRU92_RS03440 (RRU92_03440) comGD/cglD 672343..672777 (+) 435 WP_075230215.1 competence type IV pilus minor pilin ComGD Machinery gene
  RRU92_RS03445 (RRU92_03445) comGE/cglE 672740..673042 (+) 303 WP_315640434.1 competence type IV pilus minor pilin ComGE Machinery gene
  RRU92_RS03450 (RRU92_03450) comGF/cglF 673005..673466 (+) 462 WP_315640436.1 competence type IV pilus minor pilin ComGF Machinery gene
  RRU92_RS03455 (RRU92_03455) comGG 673444..673881 (+) 438 WP_315640437.1 competence type IV pilus minor pilin ComGG -
  RRU92_RS03460 (RRU92_03460) - 673940..674641 (+) 702 WP_315640440.1 histidine phosphatase family protein -
  RRU92_RS03465 (RRU92_03465) - 674831..676537 (+) 1707 WP_315640441.1 ABC transporter ATP-binding protein -

Sequence


Protein


Download         Length: 107 a.a.        Molecular weight: 11942.11 Da        Isoelectric Point: 9.8891

>NTDB_id=886527 RRU92_RS03435 WP_315640431.1 672057..672380(+) (comGC/cglC) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
MKKMMMKLKEAKVKGFTLVEMLVVLLIISVLLLLFVPNLTKQKDAVNDKGKAAVVKVVESQAELYSLDKNEDASLSKLQA
DGRITAEQAKAYKEYHDKQKTSQTVAD

Nucleotide


Download         Length: 324 bp        

>NTDB_id=886527 RRU92_RS03435 WP_315640431.1 672057..672380(+) (comGC/cglC) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
ATGAAAAAGATGATGATGAAATTAAAAGAAGCTAAGGTAAAAGGGTTCACCCTGGTAGAAATGTTGGTGGTGTTGCTTAT
CATTAGCGTCCTACTCTTACTGTTTGTGCCAAATCTTACTAAGCAAAAGGATGCAGTCAATGATAAGGGGAAAGCAGCTG
TCGTCAAGGTGGTAGAAAGCCAAGCTGAACTCTATAGTCTGGATAAAAATGAAGATGCTAGTCTAAGCAAATTACAGGCA
GATGGACGTATCACTGCTGAGCAAGCAAAAGCTTACAAAGAGTATCATGATAAACAAAAGACAAGTCAAACAGTTGCGGA
TTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

92.523

100

0.925

  comGC/cglC Streptococcus pneumoniae D39

89.899

92.523

0.832

  comGC/cglC Streptococcus pneumoniae R6

89.899

92.523

0.832

  comGC/cglC Streptococcus pneumoniae Rx1

89.899

92.523

0.832

  comGC/cglC Streptococcus mitis SK321

89.899

92.523

0.832

  comGC/cglC Streptococcus pneumoniae TIGR4

88.889

92.523

0.822

  comYC Streptococcus gordonii str. Challis substr. CH1

66.667

98.131

0.654

  comYC Streptococcus mutans UA140

67.01

90.654

0.607

  comYC Streptococcus mutans UA159

67.01

90.654

0.607

  comYC Streptococcus suis isolate S10

70.455

82.243

0.579

  comGC Lactococcus lactis subsp. cremoris KW2

55.882

95.327

0.533