Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   RRU92_RS03445 Genome accession   NZ_CP135436
Coordinates   672740..673042 (+) Length   100 a.a.
NCBI ID   WP_315640434.1    Uniprot ID   A0AA96MP97
Organism   Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 667740..678042
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RRU92_RS03415 (RRU92_03415) - 668524..669582 (+) 1059 WP_315640425.1 zinc-dependent alcohol dehydrogenase family protein -
  RRU92_RS03420 (RRU92_03420) - 669720..670097 (+) 378 WP_315640427.1 DUF1033 family protein -
  RRU92_RS03425 (RRU92_03425) comGA/cglA/cilD 670151..671092 (+) 942 WP_070676995.1 competence type IV pilus ATPase ComGA Machinery gene
  RRU92_RS03430 (RRU92_03430) comGB/cglB 671013..672056 (+) 1044 WP_315640429.1 competence type IV pilus assembly protein ComGB Machinery gene
  RRU92_RS03435 (RRU92_03435) comGC/cglC 672057..672380 (+) 324 WP_315640431.1 competence type IV pilus major pilin ComGC Machinery gene
  RRU92_RS03440 (RRU92_03440) comGD/cglD 672343..672777 (+) 435 WP_075230215.1 competence type IV pilus minor pilin ComGD Machinery gene
  RRU92_RS03445 (RRU92_03445) comGE/cglE 672740..673042 (+) 303 WP_315640434.1 competence type IV pilus minor pilin ComGE Machinery gene
  RRU92_RS03450 (RRU92_03450) comGF/cglF 673005..673466 (+) 462 WP_315640436.1 competence type IV pilus minor pilin ComGF Machinery gene
  RRU92_RS03455 (RRU92_03455) comGG 673444..673881 (+) 438 WP_315640437.1 competence type IV pilus minor pilin ComGG -
  RRU92_RS03460 (RRU92_03460) - 673940..674641 (+) 702 WP_315640440.1 histidine phosphatase family protein -
  RRU92_RS03465 (RRU92_03465) - 674831..676537 (+) 1707 WP_315640441.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11283.27 Da        Isoelectric Point: 9.8934

>NTDB_id=886529 RRU92_RS03445 WP_315640434.1 672740..673042(+) (comGE/cglE) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
MERLNVFKKQKIKAVILLEAVISLAIFASITTLLLGQIQESRKREAELLKQEEVLRVARMALQTGQKQLTVNGLTVHVVS
NEQGLEVHHGTEKLLEIQDK

Nucleotide


Download         Length: 303 bp        

>NTDB_id=886529 RRU92_RS03445 WP_315640434.1 672740..673042(+) (comGE/cglE) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
ATGGAAAGATTAAACGTATTCAAGAAGCAAAAAATTAAGGCTGTTATTTTACTAGAGGCAGTGATTTCACTAGCCATTTT
TGCAAGTATTACAACCCTCTTGCTGGGACAAATTCAAGAAAGTAGAAAAAGAGAAGCAGAGCTTCTAAAACAGGAAGAAG
TTTTGCGAGTGGCTCGTATGGCTTTGCAGACTGGACAAAAGCAGTTGACTGTCAATGGCCTTACGGTTCATGTTGTCTCG
AATGAGCAAGGTTTGGAGGTACACCATGGAACGGAGAAATTACTGGAGATTCAAGATAAGTAG

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

65

100

0.65
  comGE/cglE Streptococcus pneumoniae D39

65

100

0.65
  comGE/cglE Streptococcus pneumoniae R6

65

100

0.65
  comGE/cglE Streptococcus pneumoniae TIGR4

65

100

0.65
  comGE/cglE Streptococcus mitis NCTC 12261

64

100

0.64
  comGE/cglE Streptococcus mitis SK321

64.646

99

0.64
  comYE Streptococcus mutans UA140

44.086

93

0.41
  comYE Streptococcus mutans UA159

44.086

93

0.41