Detailed information NTG0880899

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: WMY90_RS08035
• Genome accession: NZ_CP150875
• Coordinates: 1552052..1552378 (+)
• Length: 108 a.a.
• NCBI ID: WP_002946126.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain TCI125
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1547052..1557378

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WMY90_RS08020 (WMY90_08020)	-	1549689..1550051 (+)	363	WP_011226630.1	DUF1033 family protein	-
WMY90_RS08025 (WMY90_08025)	comGA/cglA/cilD	1550132..1551073 (+)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
WMY90_RS08030 (WMY90_08030)	comGB	1550955..1552055 (+)	1101	WP_116920398.1	competence type IV pilus assembly protein ComGB	Machinery gene
WMY90_RS08035 (WMY90_08035)	comGC	1552052..1552378 (+)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
WMY90_RS08040 (WMY90_08040)	comGD	1552338..1552766 (+)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
WMY90_RS08045 (WMY90_08045)	comGE	1552738..1553031 (+)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	Machinery gene
WMY90_RS08050 (WMY90_08050)	comGF	1553015..1553452 (+)	438	WP_022096897.1	competence type IV pilus minor pilin ComGF	Machinery gene
WMY90_RS08055 (WMY90_08055)	comGG	1553430..1553747 (+)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	Machinery gene
WMY90_RS08060 (WMY90_08060)	comGH	1553792..1554748 (+)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
WMY90_RS08065 (WMY90_08065)	-	1554804..1555997 (+)	1194	WP_022096898.1	acetate kinase	-
WMY90_RS08070 (WMY90_08070)	-	1556246..1556443 (+)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
WMY90_RS08075 (WMY90_08075)	-	1556686..1557111 (+)	426	WP_014608739.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 11914.00 Da
• Isoelectric Point: 9.9219

>NTDB_id=880899 WMY90_RS08035 WP_002946126.1 1552052..1552378(+) (comGC) [Streptococcus thermophilus strain TCI125]
MKLMLKKLNAVKLRAFTLIEMLVVLLIISILLLLFVPNLSKQKDSVKETGNAAVVKVVDSQAELYEMKNNKTASLAALVS
EGQITQKQADSYNDYYAKHGGESRSVAN

Nucleotide

• Length: 327 bp

>NTDB_id=880899 WMY90_RS08035 WP_002946126.1 1552052..1552378(+) (comGC) [Streptococcus thermophilus strain TCI125]
ATGAAATTGATGTTAAAAAAATTGAATGCCGTTAAATTACGAGCCTTTACTCTGATTGAAATGCTAGTCGTACTTCTCAT
TATCAGTATTCTCCTTTTGCTCTTTGTTCCTAACTTAAGCAAGCAGAAGGATTCCGTTAAGGAAACTGGAAATGCGGCTG
TAGTCAAGGTCGTGGATTCTCAGGCAGAACTTTATGAAATGAAGAATAACAAGACAGCTAGCTTGGCAGCTCTTGTTTCA
GAAGGTCAAATTACGCAAAAACAGGCAGATTCATACAATGATTACTATGCGAAACATGGTGGTGAAAGCCGCTCAGTGGC
CAATTAG

Domains

Predicted by InterProScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (14-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Streptococcus mutans UA140	69.231	96.296	0.667
comGC	Streptococcus mutans UA159	69.231	96.296	0.667
comGC	Streptococcus gordonii str. Challis substr. CH1	63.81	97.222	0.62
comGC/cglC	Streptococcus mitis SK321	62.264	98.148	0.611
comGC/cglC	Streptococcus mitis NCTC 12261	58.333	100	0.583
comGC/cglC	Streptococcus pneumoniae D39	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae R6	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae Rx1	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae TIGR4	58.491	98.148	0.574
comGC	Lactococcus lactis subsp. cremoris KW2	56.604	98.148	0.556
comGC	Streptococcus suis isolate S10	60.227	81.481	0.491
comGC	Staphylococcus aureus MW2	50	72.222	0.361
comGC	Staphylococcus aureus N315	50	72.222	0.361