Detailed information NTG0880898

Bioinformatically predicted

Overview

• Name: comGB
• Type: Machinery gene
• Locus tag: WMY90_RS08030
• Genome accession: NZ_CP150875
• Coordinates: 1550955..1552055 (+)
• Length: 366 a.a.
• NCBI ID: WP_116920398.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain TCI125
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1545955..1557055

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WMY90_RS08020 (WMY90_08020)	-	1549689..1550051 (+)	363	WP_011226630.1	DUF1033 family protein	-
WMY90_RS08025 (WMY90_08025)	comGA/cglA/cilD	1550132..1551073 (+)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
WMY90_RS08030 (WMY90_08030)	comGB	1550955..1552055 (+)	1101	WP_116920398.1	competence type IV pilus assembly protein ComGB	Machinery gene
WMY90_RS08035 (WMY90_08035)	comGC	1552052..1552378 (+)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
WMY90_RS08040 (WMY90_08040)	comGD	1552338..1552766 (+)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
WMY90_RS08045 (WMY90_08045)	comGE	1552738..1553031 (+)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	Machinery gene
WMY90_RS08050 (WMY90_08050)	comGF	1553015..1553452 (+)	438	WP_022096897.1	competence type IV pilus minor pilin ComGF	Machinery gene
WMY90_RS08055 (WMY90_08055)	comGG	1553430..1553747 (+)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	Machinery gene
WMY90_RS08060 (WMY90_08060)	comGH	1553792..1554748 (+)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
WMY90_RS08065 (WMY90_08065)	-	1554804..1555997 (+)	1194	WP_022096898.1	acetate kinase	-
WMY90_RS08070 (WMY90_08070)	-	1556246..1556443 (+)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41797.91 Da
• Isoelectric Point: 10.1084

>NTDB_id=880898 WMY90_RS08030 WP_116920398.1 1550955..1552055(+) (comGB) [Streptococcus thermophilus strain TCI125]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=880898 WMY90_RS08030 WP_116920398.1 1550955..1552055(+) (comGB) [Streptococcus thermophilus strain TCI125]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTAAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterProScan.

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB	Streptococcus mutans UA140	54.678	93.443	0.511
comGB	Streptococcus mutans UA159	54.678	93.443	0.511
comGB	Streptococcus gordonii str. Challis substr. CH1	51.17	93.443	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.695	89.617	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413