Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   RDV49_RS01250 Genome accession   NZ_CP133988
Coordinates   263043..263984 (-) Length   313 a.a.
NCBI ID   WP_003009757.1    Uniprot ID   A0AAX4AY99
Organism   Streptococcus parasanguinis strain B-1756     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 258043..268984
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RDV49_RS01215 (RDV49_01215) comYH 259268..260221 (-) 954 WP_003009772.1 class I SAM-dependent methyltransferase Machinery gene
  RDV49_RS01220 (RDV49_01220) comGG 260252..260689 (-) 438 WP_003009770.1 competence type IV pilus minor pilin ComGG -
  RDV49_RS01225 (RDV49_01225) comGF/cglF 260676..261128 (-) 453 WP_003009767.1 competence type IV pilus minor pilin ComGF Machinery gene
  RDV49_RS01230 (RDV49_01230) comGE 261118..261405 (-) 288 WP_003004353.1 competence type IV pilus minor pilin ComGE -
  RDV49_RS01235 (RDV49_01235) comYD 261371..261775 (-) 405 WP_003004513.1 competence type IV pilus minor pilin ComGD Machinery gene
  RDV49_RS01240 (RDV49_01240) comYC 261765..262082 (-) 318 WP_003009763.1 competence type IV pilus major pilin ComGC Machinery gene
  RDV49_RS01245 (RDV49_01245) comYB 262079..263110 (-) 1032 WP_182448484.1 competence type IV pilus assembly protein ComGB Machinery gene
  RDV49_RS01250 (RDV49_01250) comYA 263043..263984 (-) 942 WP_003009757.1 competence type IV pilus ATPase ComGA Machinery gene
  RDV49_RS01255 (RDV49_01255) - 264072..264461 (-) 390 WP_037608454.1 DUF1033 family protein -
  RDV49_RS01260 (RDV49_01260) - 264671..265774 (-) 1104 WP_003009752.1 glycosyl hydrolase family 8 -
  RDV49_RS01265 (RDV49_01265) - 265783..267093 (-) 1311 WP_003009751.1 glycosyltransferase -
  RDV49_RS01270 (RDV49_01270) - 267086..267226 (-) 141 WP_003009749.1 hypothetical protein -
  RDV49_RS01275 (RDV49_01275) - 267236..268024 (-) 789 WP_003009746.1 hypothetical protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35888.29 Da        Isoelectric Point: 6.7632

>NTDB_id=878149 RDV49_RS01250 WP_003009757.1 263043..263984(-) (comYA) [Streptococcus parasanguinis strain B-1756]
MVQEIAKKLIRMGKKEEAQDLYFIPRKEEYQVFMRVGDERRFVQSFPFEDMTAMISHFKFVAGMNVGEKRRSQLGSCDYP
LENGVVSIRLSTVGDYRGYESLVIRLLHDEERELRFWFDQLPDLKKKLAGRGLYLFAGPVGSGKTTLMHALAQERFADQQ
VMSIEDPVEIKQDNMLQLQLNDQIGMTYDNLIKLSLRHRPDLLIIGEIRDKETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVSEEELKIVLQGICYQRLIAGGGVVDFATENYQEHSASRWNQQMDLLAQSGYIQLAQAQAEKIIYR

Nucleotide


Download         Length: 942 bp        

>NTDB_id=878149 RDV49_RS01250 WP_003009757.1 263043..263984(-) (comYA) [Streptococcus parasanguinis strain B-1756]
ATGGTTCAAGAAATTGCAAAAAAACTGATCCGTATGGGAAAAAAGGAAGAGGCTCAGGATCTTTACTTCATTCCTCGGAA
GGAGGAGTACCAAGTTTTTATGAGGGTGGGAGACGAGAGGCGCTTTGTGCAGTCCTTCCCTTTTGAGGACATGACGGCTA
TGATTAGCCACTTTAAGTTCGTGGCAGGGATGAATGTGGGAGAAAAAAGGCGCAGCCAGCTAGGATCGTGTGATTACCCT
TTGGAGAATGGAGTGGTCTCGATTCGCTTGTCGACGGTGGGGGATTATCGTGGTTATGAAAGCTTGGTCATTCGGCTCTT
GCATGATGAGGAACGTGAATTGCGGTTTTGGTTTGATCAGTTGCCGGACTTGAAGAAGAAATTGGCTGGTCGTGGCCTCT
ATCTCTTTGCAGGTCCTGTTGGTTCGGGAAAGACCACTCTCATGCATGCGTTGGCGCAAGAGCGCTTTGCGGACCAGCAA
GTCATGTCTATTGAAGACCCTGTCGAGATCAAGCAGGACAATATGCTTCAACTTCAGCTGAATGACCAGATCGGCATGAC
CTATGACAACCTGATCAAACTCTCCTTACGCCATCGGCCGGACCTTCTCATCATTGGAGAGATCCGAGATAAGGAAACAG
CTCGTGCAGTCGTACGAGCTAGTTTGACAGGAGTCACCGTCTTCTCTACTATTCATGCCAAGAGCGTTCGAGGTGTTTAT
GAGAGGCTCTTAGAACTTGGAGTGAGTGAGGAAGAGCTCAAGATTGTTTTACAAGGTATTTGCTACCAACGATTAATTGC
AGGAGGAGGTGTGGTCGATTTTGCGACGGAAAACTACCAAGAGCACTCAGCCAGCCGCTGGAACCAACAAATGGATCTCT
TGGCTCAATCGGGATATATCCAGCTGGCTCAGGCCCAAGCCGAAAAAATTATCTACCGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(15-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

73.548

99.042

0.728
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

71.795

99.681

0.716
  comGA/cglA/cilD Streptococcus pneumoniae D39

71.474

99.681

0.712
  comGA/cglA/cilD Streptococcus pneumoniae R6

71.474

99.681

0.712
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

71.474

99.681

0.712
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

71.474

99.681

0.712
  comYA Streptococcus mutans UA159

64.952

99.361

0.645
  comYA Streptococcus mutans UA140

64.952

99.361

0.645
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.258

99.042

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

99.681

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

42.086

88.818

0.374