Detailed information NTG0878145

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: RDV49_RS01225
• Genome accession: NZ_CP133988
• Coordinates: 260676..261128 (-)
• Length: 150 a.a.
• NCBI ID: WP_003009767.1
• Uniprot ID: A0AAX4AXT8
• Organism: Streptococcus parasanguinis strain B-1756
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 255676..266128

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RDV49_RS01200 (RDV49_01200)	folP	256106..257056 (-)	951	WP_003009783.1	dihydropteroate synthase	-
RDV49_RS01205 (RDV49_01205)	-	257219..257950 (-)	732	WP_037608245.1	CPBP family intramembrane glutamic endopeptidase	-
RDV49_RS01210 (RDV49_01210)	-	258023..259216 (-)	1194	WP_003009777.1	acetate kinase	-
RDV49_RS01215 (RDV49_01215)	comYH	259268..260221 (-)	954	WP_003009772.1	class I SAM-dependent methyltransferase	Machinery gene
RDV49_RS01220 (RDV49_01220)	comGG	260252..260689 (-)	438	WP_003009770.1	competence type IV pilus minor pilin ComGG	-
RDV49_RS01225 (RDV49_01225)	comGF/cglF	260676..261128 (-)	453	WP_003009767.1	competence type IV pilus minor pilin ComGF	Machinery gene
RDV49_RS01230 (RDV49_01230)	comGE	261118..261405 (-)	288	WP_003004353.1	competence type IV pilus minor pilin ComGE	-
RDV49_RS01235 (RDV49_01235)	comYD	261371..261775 (-)	405	WP_003004513.1	competence type IV pilus minor pilin ComGD	Machinery gene
RDV49_RS01240 (RDV49_01240)	comYC	261765..262082 (-)	318	WP_003009763.1	competence type IV pilus major pilin ComGC	Machinery gene
RDV49_RS01245 (RDV49_01245)	comYB	262079..263110 (-)	1032	WP_182448484.1	competence type IV pilus assembly protein ComGB	Machinery gene
RDV49_RS01250 (RDV49_01250)	comYA	263043..263984 (-)	942	WP_003009757.1	competence type IV pilus ATPase ComGA	Machinery gene
RDV49_RS01255 (RDV49_01255)	-	264072..264461 (-)	390	WP_037608454.1	DUF1033 family protein	-
RDV49_RS01260 (RDV49_01260)	-	264671..265774 (-)	1104	WP_003009752.1	glycosyl hydrolase family 8	-

Sequence

Protein

• Length: 150 a.a.
• Molecular weight: 17296.74 Da
• Isoelectric Point: 6.2263

>NTDB_id=878145 RDV49_RS01225 WP_003009767.1 260676..261128(-) (comGF/cglF) [Streptococcus parasanguinis strain B-1756]
MWNKGKVKAFTLLEALVALLVLSGGVLVFQGLTKLLHAELDYQAHQKQEEWILFQQQLQVELDRSHFEKVADNHIYLVQD
QKPIAIGQSKGDDIRKTDDKGRGYQPIISGVRSSQIWQEGELIHLRLNFEEGLEREYVYHVVPAMQNEKS

Nucleotide

• Length: 453 bp

>NTDB_id=878145 RDV49_RS01225 WP_003009767.1 260676..261128(-) (comGF/cglF) [Streptococcus parasanguinis strain B-1756]
ATGTGGAATAAAGGAAAGGTCAAGGCCTTTACCCTGCTCGAAGCCTTGGTCGCTCTCTTGGTGCTCAGTGGGGGTGTGTT
GGTCTTTCAAGGCTTGACCAAGCTCCTGCATGCTGAATTGGACTACCAGGCGCATCAAAAGCAGGAAGAATGGATACTTT
TTCAGCAACAATTGCAGGTGGAATTGGATCGGAGCCATTTTGAAAAAGTAGCGGACAATCATATCTACTTGGTTCAGGAT
CAAAAACCAATTGCCATTGGTCAATCTAAAGGAGATGATATCCGAAAAACAGATGATAAGGGCAGGGGCTATCAGCCTAT
AATTTCAGGGGTTCGCTCTAGCCAAATTTGGCAGGAGGGAGAGTTGATTCATCTGCGGTTGAATTTCGAAGAAGGTCTAG
AAAGGGAGTATGTCTACCATGTGGTACCAGCGATGCAAAATGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (43-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus mitis NCTC 12261	54.676	92.667	0.507
comGF/cglF	Streptococcus mitis SK321	53.957	92.667	0.5
comGF/cglF	Streptococcus pneumoniae Rx1	55.147	90.667	0.5
comGF/cglF	Streptococcus pneumoniae D39	55.147	90.667	0.5
comGF/cglF	Streptococcus pneumoniae R6	55.147	90.667	0.5
comGF/cglF	Streptococcus pneumoniae TIGR4	55.147	90.667	0.5
comYF	Streptococcus mutans UA159	42.647	90.667	0.387
comYF	Streptococcus mutans UA140	42.647	90.667	0.387
comGF	Lactococcus lactis subsp. cremoris KW2	38.298	94	0.36