Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   RDV49_RS01245 Genome accession   NZ_CP133988
Coordinates   262079..263110 (-) Length   343 a.a.
NCBI ID   WP_182448484.1    Uniprot ID   A0AAX4AZT1
Organism   Streptococcus parasanguinis strain B-1756     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 257079..268110
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RDV49_RS01205 (RDV49_01205) - 257219..257950 (-) 732 WP_037608245.1 CPBP family intramembrane glutamic endopeptidase -
  RDV49_RS01210 (RDV49_01210) - 258023..259216 (-) 1194 WP_003009777.1 acetate kinase -
  RDV49_RS01215 (RDV49_01215) comYH 259268..260221 (-) 954 WP_003009772.1 class I SAM-dependent methyltransferase Machinery gene
  RDV49_RS01220 (RDV49_01220) comGG 260252..260689 (-) 438 WP_003009770.1 competence type IV pilus minor pilin ComGG -
  RDV49_RS01225 (RDV49_01225) comGF/cglF 260676..261128 (-) 453 WP_003009767.1 competence type IV pilus minor pilin ComGF Machinery gene
  RDV49_RS01230 (RDV49_01230) comGE 261118..261405 (-) 288 WP_003004353.1 competence type IV pilus minor pilin ComGE -
  RDV49_RS01235 (RDV49_01235) comYD 261371..261775 (-) 405 WP_003004513.1 competence type IV pilus minor pilin ComGD Machinery gene
  RDV49_RS01240 (RDV49_01240) comYC 261765..262082 (-) 318 WP_003009763.1 competence type IV pilus major pilin ComGC Machinery gene
  RDV49_RS01245 (RDV49_01245) comYB 262079..263110 (-) 1032 WP_182448484.1 competence type IV pilus assembly protein ComGB Machinery gene
  RDV49_RS01250 (RDV49_01250) comYA 263043..263984 (-) 942 WP_003009757.1 competence type IV pilus ATPase ComGA Machinery gene
  RDV49_RS01255 (RDV49_01255) - 264072..264461 (-) 390 WP_037608454.1 DUF1033 family protein -
  RDV49_RS01260 (RDV49_01260) - 264671..265774 (-) 1104 WP_003009752.1 glycosyl hydrolase family 8 -
  RDV49_RS01265 (RDV49_01265) - 265783..267093 (-) 1311 WP_003009751.1 glycosyltransferase -
  RDV49_RS01270 (RDV49_01270) - 267086..267226 (-) 141 WP_003009749.1 hypothetical protein -
  RDV49_RS01275 (RDV49_01275) - 267236..268024 (-) 789 WP_003009746.1 hypothetical protein -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 39297.24 Da        Isoelectric Point: 9.7442

>NTDB_id=878148 RDV49_RS01245 WP_182448484.1 262079..263110(-) (comYB) [Streptococcus parasanguinis strain B-1756]
MSWLNRDISSWLRPKPKKLSTAKQKQIIELFLNLYSSGFHLSEIVDFLDRSHLVESRLVSQMREDLSRGRSFSEMMAGIG
FSDAVTTQLSLAELHGNLALSLKKISAYLENMRKVKKKLIEVSTYPLILLGFLVLIMLGLRNYLLPQMDAQNIGTQLISS
FPQLFLALGAGLVTFFLLGFLYYRKSGKINVFRTLSHLPFGKGMIQAYLTAYYAREWGNLIGQGLELSQIFSMMQEQKSQ
LFQEIGRDLALSLDRGQSFSETVRGYPFFKKELPLMIEYGEVKSKLGSELEIYAEKTWEDFFRQVHKAMNVIQPLVFVFV
ALVIVLLYAAMLLPIYQNMEVHL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=878148 RDV49_RS01245 WP_182448484.1 262079..263110(-) (comYB) [Streptococcus parasanguinis strain B-1756]
ATCTCTTGGCTCAATCGGGATATATCCAGCTGGCTCAGGCCCAAGCCGAAAAAATTATCTACCGCTAAACAAAAGCAAAT
TATTGAATTGTTTTTGAATCTTTATTCGAGTGGTTTTCATCTGTCTGAGATCGTCGATTTTCTGGATCGCTCCCACCTAG
TGGAGAGTCGTTTGGTTTCCCAGATGCGAGAGGATCTCTCGCGGGGCCGGAGTTTTTCAGAGATGATGGCGGGGATCGGT
TTTTCAGATGCAGTGACGACACAGCTGTCTCTCGCTGAGCTCCATGGCAATCTTGCATTGAGCTTGAAGAAAATCAGTGC
TTATTTAGAAAACATGCGCAAGGTCAAGAAAAAGCTGATTGAGGTGAGCACTTATCCTCTTATCTTACTTGGGTTTTTAG
TTTTGATTATGCTAGGCCTGCGTAATTATTTGCTCCCTCAAATGGATGCTCAAAATATTGGGACACAATTGATCAGTTCC
TTCCCCCAACTCTTTTTGGCCTTAGGAGCGGGACTGGTGACCTTCTTCTTACTCGGCTTTCTCTATTATCGGAAGTCGGG
CAAGATCAACGTTTTTAGAACCTTGTCTCATTTGCCTTTCGGAAAAGGCATGATTCAAGCTTATTTGACAGCCTATTATG
CCAGAGAATGGGGCAATCTGATTGGGCAAGGATTGGAATTGTCTCAGATTTTTTCCATGATGCAGGAGCAAAAATCCCAG
CTTTTTCAAGAAATTGGGAGGGACTTAGCTCTTTCTTTAGATCGTGGCCAGTCCTTTTCAGAAACGGTCAGGGGGTATCC
TTTTTTCAAAAAAGAATTGCCCCTTATGATTGAATATGGTGAAGTCAAATCAAAGCTCGGAAGTGAGTTAGAGATCTACG
CTGAAAAAACATGGGAAGATTTCTTTCGTCAGGTTCACAAGGCCATGAATGTGATACAACCCTTGGTGTTTGTCTTTGTG
GCTCTTGTGATTGTGTTACTCTATGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGGTTCATTTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)

Type II secretion system (T2SS), protein F (T2SSF)

(28-146)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

65.598

100

0.656
  comGB/cglB Streptococcus mitis SK321

66.369

97.959

0.65
  comGB/cglB Streptococcus mitis NCTC 12261

65.774

97.959

0.644
  comGB/cglB Streptococcus pneumoniae TIGR4

65.476

97.959

0.641
  comGB/cglB Streptococcus pneumoniae R6

65.476

97.959

0.641
  comGB/cglB Streptococcus pneumoniae Rx1

65.476

97.959

0.641
  comGB/cglB Streptococcus pneumoniae D39

65.476

97.959

0.641
  comYB Streptococcus mutans UA159

57.88

100

0.589
  comYB Streptococcus mutans UA140

57.88

100

0.589
  comGB Lactococcus lactis subsp. cremoris KW2

48.961

98.251

0.481