Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/comX2   Type   Regulator
Locus tag   QL280_RS09210 Genome accession   NZ_CP125291
Coordinates   1793677..1794156 (-) Length   159 a.a.
NCBI ID   WP_000588900.1    Uniprot ID   A0A4J2BPQ8
Organism   Streptococcus pneumoniae strain 105_Kz     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1788677..1799156
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QL280_RS09210 (QL280_09210) comX/comX2 1793677..1794156 (-) 480 WP_000588900.1 sigma-70 family RNA polymerase sigma factor Regulator
  QL280_RS09215 (QL280_09215) nusG 1794278..1794814 (-) 537 WP_000376736.1 transcription termination/antitermination protein NusG -
  QL280_RS09220 (QL280_09220) secE 1794869..1795045 (-) 177 WP_001210991.1 preprotein translocase subunit SecE -
  QL280_RS09225 (QL280_09225) rpmG 1795055..1795207 (-) 153 WP_001809375.1 50S ribosomal protein L33 -
  QL280_RS09230 (QL280_09230) pbp2a 1795260..1797455 (-) 2196 WP_000762625.1 penicillin-binding protein PBP2A -
  QL280_RS09235 (QL280_09235) - 1797542..1798417 (+) 876 WP_001810600.1 RluA family pseudouridine synthase -

Sequence

Protein


Download         Length: 159 a.a.        Molecular weight: 19899.55 Da        Isoelectric Point: 7.3186

>NTDB_id=830848 QL280_RS09210 WP_000588900.1 1793677..1794156(-) (comX/comX2) [Streptococcus pneumoniae strain 105_Kz]
MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTY

Nucleotide


Download         Length: 480 bp        

>NTDB_id=830848 QL280_RS09210 WP_000588900.1 1793677..1794156(-) (comX/comX2) [Streptococcus pneumoniae strain 105_Kz]
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
GTCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAGA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGATCAGTCATCGTATAAGTGAGGGGGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCTATTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4J2BPQ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/comX2 Streptococcus pneumoniae Rx1

99.371

100

0.994
  comX/comX1 Streptococcus pneumoniae Rx1

99.371

100

0.994
  comX/comX2 Streptococcus pneumoniae D39

99.371

100

0.994
  comX/comX1 Streptococcus pneumoniae D39

99.371

100

0.994
  comX/comX2 Streptococcus pneumoniae R6

99.371

100

0.994
  comX/comX1 Streptococcus pneumoniae R6

99.371

100

0.994
  comX/comX2 Streptococcus pneumoniae TIGR4

98.742

100

0.987
  comX/comX1 Streptococcus pneumoniae TIGR4

98.742

100

0.987
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

91.824

100

0.918
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

91.824

100

0.918
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

91.139

99.371

0.906
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

89.241

99.371

0.887
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

48.718

98.113

0.478
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

48.718

98.113

0.478
  comX/sigX Streptococcus mutans UA159

46

94.34

0.434
  comX/sigX Streptococcus suis isolate S10

45.695

94.969

0.434
  comX/sigX Streptococcus suis D9

45.695

94.969

0.434
  comX/sigX Streptococcus suis P1/7

45.695

94.969

0.434
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

39.216

96.226

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

39.216

96.226

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

40

94.34

0.377
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

40

94.34

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

40

94.34

0.377
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

40

94.34

0.377