Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   H7677_RS00725 Genome accession   NZ_AP023391
Coordinates   114609..115559 (+) Length   316 a.a.
NCBI ID   WP_184493705.1    Uniprot ID   -
Organism   Streptococcus suis strain DAT299     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 109609..120559
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7677_RS00715 (DAT299_01060) - 113173..113538 (+) 366 WP_002936568.1 DUF1033 family protein -
  H7677_RS00720 (DAT299_01070) - 113573..114523 (-) 951 WP_184493703.1 S66 peptidase family protein -
  H7677_RS00725 (DAT299_01080) comYA 114609..115559 (+) 951 WP_184493705.1 competence type IV pilus ATPase ComGA Machinery gene
  H7677_RS00730 (DAT299_01090) comYB 115471..116508 (+) 1038 WP_269473649.1 competence type IV pilus assembly protein ComGB Machinery gene
  H7677_RS00735 (DAT299_01100) comYC 116510..116791 (+) 282 WP_184493707.1 competence type IV pilus major pilin ComGC Machinery gene
  H7677_RS00740 (DAT299_01110) comGD 116772..117179 (+) 408 WP_184493709.1 competence type IV pilus minor pilin ComGD -
  H7677_RS00745 (DAT299_01120) comYE 117151..117444 (+) 294 WP_011921722.1 competence type IV pilus minor pilin ComGE Machinery gene
  H7677_RS00750 (DAT299_01130) comGF/cglF 117431..117865 (+) 435 WP_079268055.1 competence type IV pilus minor pilin ComGF Machinery gene
  H7677_RS00755 (DAT299_01140) comGG 117843..118370 (+) 528 WP_184493711.1 competence type IV pilus minor pilin ComGG -
  H7677_RS00760 (DAT299_01150) comYH 118427..119380 (+) 954 WP_184493713.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35486.40 Da        Isoelectric Point: 5.4744

>NTDB_id=82875 H7677_RS00725 WP_184493705.1 114609..115559(+) (comYA) [Streptococcus suis strain DAT299]
MIQEKARKMIEEAVADRVSDIYLVPRGECYQVYHRIMDEREFVQDMAEEEVIAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSTDQWNAQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=82875 H7677_RS00725 WP_184493705.1 114609..115559(+) (comYA) [Streptococcus suis strain DAT299]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCAGATAGGGTCAGTGACATCTATCTAGTTCCTCGAGG
TGAGTGTTACCAAGTCTATCATCGTATCATGGACGAGCGGGAATTTGTGCAAGACATGGCTGAGGAGGAAGTAATAGCCA
TCATTAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGGTCCTGTGACTATGAT
TATGGGAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGAGATTATCGTGGCAAGGAAAGTTTGGTTATCCGCCTGCT
TTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGACCCTGTCGAAATCAAACAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTATGACAATCTGATCAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATCATCGGTGAAATTCGGGATGCGGAAACTG
CTCGAGCAGTCATTCGAGCCAGCCTGACGGGAGCTACCGTTTTCTCAACAGTTCATGCAAGGTCTATTTCAGGTGTCTAT
GCCCGTATGTTGGAACTGGGGGTCAGTCCTGAAGAGCTAAATAATGCCCTTCAAGGCATTGCCTATCAACGTTTAATCGG
GGGAGGAGGTGTAGTGGATTTTGCAAAAGGAAATTACCAAAACCATTCCACAGACCAGTGGAATGCGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

69.032

98.101

0.677
  comYA Streptococcus mutans UA159

67.524

98.418

0.665
  comYA Streptococcus mutans UA140

67.524

98.418

0.665
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.952

98.418

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.516

98.101

0.633
  comGA Lactococcus lactis subsp. cremoris KW2

53.312

100

0.535

Multiple sequence alignment