Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   H7677_RS00730 Genome accession   NZ_AP023391
Coordinates   115471..116508 (+) Length   345 a.a.
NCBI ID   WP_269473649.1    Uniprot ID   -
Organism   Streptococcus suis strain DAT299     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 110471..121508
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7677_RS00715 (DAT299_01060) - 113173..113538 (+) 366 WP_002936568.1 DUF1033 family protein -
  H7677_RS00720 (DAT299_01070) - 113573..114523 (-) 951 WP_184493703.1 S66 peptidase family protein -
  H7677_RS00725 (DAT299_01080) comYA 114609..115559 (+) 951 WP_184493705.1 competence type IV pilus ATPase ComGA Machinery gene
  H7677_RS00730 (DAT299_01090) comYB 115471..116508 (+) 1038 WP_269473649.1 competence type IV pilus assembly protein ComGB Machinery gene
  H7677_RS00735 (DAT299_01100) comYC 116510..116791 (+) 282 WP_184493707.1 competence type IV pilus major pilin ComGC Machinery gene
  H7677_RS00740 (DAT299_01110) comGD 116772..117179 (+) 408 WP_184493709.1 competence type IV pilus minor pilin ComGD -
  H7677_RS00745 (DAT299_01120) comYE 117151..117444 (+) 294 WP_011921722.1 competence type IV pilus minor pilin ComGE Machinery gene
  H7677_RS00750 (DAT299_01130) comGF/cglF 117431..117865 (+) 435 WP_079268055.1 competence type IV pilus minor pilin ComGF Machinery gene
  H7677_RS00755 (DAT299_01140) comGG 117843..118370 (+) 528 WP_184493711.1 competence type IV pilus minor pilin ComGG -
  H7677_RS00760 (DAT299_01150) comYH 118427..119380 (+) 954 WP_184493713.1 class I SAM-dependent methyltransferase Machinery gene
  H7677_RS00765 (DAT299_01160) - 119430..120617 (+) 1188 WP_184493715.1 acetate kinase -
  H7677_RS00770 (DAT299_01170) - 120932..121483 (+) 552 WP_184493717.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 38940.92 Da        Isoelectric Point: 9.3127

>NTDB_id=82876 H7677_RS00730 WP_269473649.1 115471..116508(+) (comYB) [Streptococcus suis strain DAT299]
MRKLIAFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLIHIQSYLENVSKVRKKLIEVATYPIILLGFLLLIMLGLKNYLLPQLEEGNAATA
LINHLPTIFLSLSGLSLVAVLAGMVWFRKTNKIKVFSCLAALPFFGKLIQTYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGSELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=82876 H7677_RS00730 WP_269473649.1 115471..116508(+) (comYB) [Streptococcus suis strain DAT299]
ATGCGCAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCG
CCAGCGTAAGGTCATTGAGCTTTTCAATAATCTCTTTGCCAGTGGTTTTCATCTAGGGGAGATTGTTGATTTCCTCAAAC
GCAGTCAGCTTCTGGCAGATCCCTATACCCAGGTCTTGTCAGACGGGCTGTTAGCAGGCAAACCCTTTTCAAGTTTGCTG
GCGGATTTGCGTTTTTCAGATGCGGTGGTCACACAGGTGGCTTTGGCAGAAGTTCATGGCAATACCAGCCTGAGTTTGAT
TCATATCCAGTCCTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAGCTGATTGAGGTGGCGACCTATCCGATTATATTGC
TTGGTTTTCTGCTTTTGATTATGCTTGGCTTGAAAAACTATCTTCTGCCCCAGTTGGAGGAAGGCAATGCAGCGACAGCG
CTGATTAATCATCTACCGACCATCTTTTTATCTCTAAGTGGACTTAGTTTGGTGGCGGTCTTAGCTGGTATGGTTTGGTT
TCGCAAAACCAATAAAATTAAGGTCTTTTCCTGCTTGGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTACCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGCTTGGACCTGCCGCAGATTGTGGGCTTGATGCAAGAG
CAGCAGTCGCAGCTTTTTCGGGAGATTGGGCAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGTTTTCACGAACACAT
TAAGACCTACGCCTTTTTTAAGCGGGAGCTGAGTTTGATTGTCGAGTACGGTCAGGTCAAGTCCAAGTTGGGTAGCGAGT
TGACAGTTTATGCGGCTGAATGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGCTAATCCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATCTACGCAGCCATGCTGCTGCCGATTTATCAGAATATGGAGTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.743

99.13

0.632
  comGB/cglB Streptococcus mitis NCTC 12261

60.896

97.101

0.591
  comYB Streptococcus mutans UA140

59.184

99.42

0.588
  comYB Streptococcus mutans UA159

59.184

99.42

0.588
  comGB/cglB Streptococcus mitis SK321

60.597

97.101

0.588
  comGB/cglB Streptococcus pneumoniae Rx1

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae D39

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae R6

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae TIGR4

60.299

97.101

0.586
  comGB Lactococcus lactis subsp. cremoris KW2

50.445

97.681

0.493

Multiple sequence alignment