Detailed information NTG0819765

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAY67_RS13480
• Genome accession: NZ_CP123160
• Coordinates: 2723509..2724396 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain BE-MSSA8
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2718509..2729396

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY67_RS13450 (QAY67_13475)	-	2718528..2718620 (+)	93	WP_010956583.1	hypothetical protein	-
QAY67_RS13455 (QAY67_13480)	-	2718728..2719225 (-)	498	WP_001065268.1	glutathione peroxidase	-
QAY67_RS13460 (QAY67_13485)	-	2719235..2719495 (-)	261	WP_001791974.1	hypothetical protein	-
QAY67_RS13465 (QAY67_13490)	-	2719877..2719990 (-)	114	Protein_2610	hypothetical protein	-
QAY67_RS13470 (QAY67_13495)	-	2720649..2722649 (-)	2001	WP_000776740.1	ABC transporter permease	-
QAY67_RS13475 (QAY67_13500)	-	2722646..2723401 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
QAY67_RS13480 (QAY67_13505)	braS	2723509..2724396 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAY67_RS13485 (QAY67_13510)	braR	2724407..2725072 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAY67_RS13490 (QAY67_13515)	-	2725098..2725298 (-)	201	WP_000604727.1	hypothetical protein	-
QAY67_RS13495 (QAY67_13520)	-	2725496..2726920 (+)	1425	WP_000953748.1	alkaline phosphatase	-
QAY67_RS13500	-	2726980..2727081 (-)	102	WP_000731972.1	SE2200 family small protein	-
QAY67_RS13505 (QAY67_13530)	-	2727203..2727658 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAY67_RS13510 (QAY67_13535)	-	2727903..2728664 (-)	762	WP_411888918.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=819765 QAY67_RS13480 WP_000143417.1 2723509..2724396(-) (braS) [Staphylococcus aureus strain BE-MSSA8]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=819765 QAY67_RS13480 WP_000143417.1 2723509..2724396(-) (braS) [Staphylococcus aureus strain BE-MSSA8]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99