Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   QAY74_RS13760 Genome accession   NZ_CP123093
Coordinates   2779888..2780604 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain MRSA-EDCC5443     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2774888..2785604
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAY74_RS13740 (QAY74_13725) - 2775981..2776931 (+) 951 WP_000790322.1 LacI family DNA-binding transcriptional regulator -
  QAY74_RS13745 (QAY74_13730) - 2777080..2778564 (+) 1485 WP_000141410.1 sucrose-6-phosphate hydrolase -
  QAY74_RS13750 (QAY74_13735) - 2778561..2779520 (+) 960 WP_001253301.1 carbohydrate kinase family protein -
  QAY74_RS13755 (QAY74_13740) - 2779709..2779816 (-) 108 WP_031789494.1 hypothetical protein -
  QAY74_RS13760 (QAY74_13745) agrA 2779888..2780604 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  QAY74_RS13765 (QAY74_13750) agrC 2780623..2781915 (-) 1293 WP_001670396.1 quorum-sensing sensor histidine kinase AgrC -
  QAY74_RS13770 (QAY74_13755) agrD 2781940..2782080 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  QAY74_RS13775 (QAY74_13760) agrB 2782077..2782646 (-) 570 WP_001105713.1 accessory gene regulator AgrB -
  QAY74_RS13780 (QAY74_13765) hld 2782936..2783016 (+) 81 WP_000046022.1 delta-hemolysin -
  QAY74_RS13785 (QAY74_13770) - 2783615..2784400 (-) 786 WP_000867943.1 carbon-nitrogen family hydrolase -
  QAY74_RS13790 (QAY74_13775) - 2784670..2785296 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=818580 QAY74_RS13760 WP_000688492.1 2779888..2780604(-) (agrA) [Staphylococcus aureus strain MRSA-EDCC5443]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=818580 QAY74_RS13760 WP_000688492.1 2779888..2780604(-) (agrA) [Staphylococcus aureus strain MRSA-EDCC5443]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATCCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCATAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACACGTATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATCGAATCTATAG
ATTCGAAAGAGCGCATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1