Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   P7Y79_RS00995 Genome accession   NZ_CP121207
Coordinates   213380..214114 (+) Length   244 a.a.
NCBI ID   WP_052071091.1    Uniprot ID   A0A091BRI3
Organism   Streptococcus ruminicola strain CNU_77-47     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 208380..219114
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P7Y79_RS00965 (P7Y79_00965) comC/comC1 208400..208552 (-) 153 WP_157327338.1 hypothetical protein Regulator
  P7Y79_RS00970 (P7Y79_00970) - 208814..208963 (+) 150 WP_278007565.1 bacteriocin -
  P7Y79_RS00975 (P7Y79_00975) - 208976..209281 (+) 306 WP_158914537.1 bacteriocin immunity protein -
  P7Y79_RS00980 (P7Y79_00980) - 209309..209431 (+) 123 WP_278007566.1 hypothetical protein -
  P7Y79_RS00985 (P7Y79_00985) comD/comD2 210393..211340 (+) 948 WP_278007567.1 GHKL domain-containing protein Regulator
  P7Y79_RS00990 (P7Y79_00990) comD/comD3 211337..212719 (+) 1383 WP_278007568.1 GHKL domain-containing protein Regulator
  P7Y79_RS00995 (P7Y79_00995) comE/comE2 213380..214114 (+) 735 WP_052071091.1 LytTR family DNA-binding domain-containing protein Regulator
  P7Y79_RS01005 (P7Y79_01005) rsgA 214432..215304 (+) 873 WP_006531894.1 ribosome small subunit-dependent GTPase A -
  P7Y79_RS01010 (P7Y79_01010) rpe 215311..215973 (+) 663 WP_006531895.1 ribulose-phosphate 3-epimerase -
  P7Y79_RS01015 (P7Y79_01015) - 215966..216598 (+) 633 WP_278007569.1 thiamine diphosphokinase -
  P7Y79_RS01020 (P7Y79_01020) - 216600..217874 (+) 1275 WP_278007570.1 DNA recombination protein RmuC -
  P7Y79_RS01025 (P7Y79_01025) - 217864..218802 (+) 939 WP_074626814.1 3'-5' exoribonuclease YhaM family protein -

Sequence

Protein


Download         Length: 244 a.a.        Molecular weight: 28825.11 Da        Isoelectric Point: 6.4989

>NTDB_id=811080 P7Y79_RS00995 WP_052071091.1 213380..214114(+) (comE/comE2) [Streptococcus ruminicola strain CNU_77-47]
MIDIYVLEDNVNQQFRIEKMIGDLLETNQWETRHFDLFSEPDCLTNLVEESFPQIFFLDIDIHGDNTKGIEVAKAIREKS
RTATIVFVTTHSEFMLLTYRAQVSALDFIDKTDKDDAIKDNLKKCLQKVFEDQGFNIPKEIFVFENNKTKIRIPLEDILY
FETAESHRLKLITKTGQRHFYGSIKEVMQANQKLFRCHKSYLINLNNIVRLDKKEGLVYFDDDKACYVSRKYIKDLRSKM
ENLK

Nucleotide


Download         Length: 735 bp        

>NTDB_id=811080 P7Y79_RS00995 WP_052071091.1 213380..214114(+) (comE/comE2) [Streptococcus ruminicola strain CNU_77-47]
ATGATTGATATCTATGTATTAGAAGATAATGTAAATCAGCAGTTCCGTATTGAAAAAATGATTGGAGATTTACTCGAGAC
AAATCAGTGGGAAACTCGTCATTTTGATTTATTTAGTGAACCTGATTGTTTAACTAACCTAGTTGAGGAGTCTTTTCCTC
AAATTTTTTTCCTGGATATTGATATTCATGGAGATAATACCAAAGGAATTGAAGTGGCTAAGGCGATAAGGGAAAAATCA
CGCACAGCGACAATTGTTTTTGTGACGACTCACTCTGAATTCATGTTATTAACTTATCGAGCGCAAGTTAGTGCACTTGA
TTTTATTGATAAAACAGATAAAGATGATGCGATAAAAGATAACTTAAAAAAATGCTTGCAAAAGGTCTTTGAGGACCAAG
GTTTTAATATTCCTAAGGAAATATTTGTTTTTGAAAATAACAAAACGAAAATCCGCATTCCCTTGGAAGATATCCTTTAT
TTTGAAACCGCGGAAAGTCATCGCCTGAAGTTGATTACAAAAACTGGACAACGTCATTTTTATGGTTCAATCAAAGAAGT
GATGCAAGCTAATCAGAAATTATTTAGATGTCATAAATCATATCTGATTAACCTAAATAATATTGTTAGGTTAGATAAAA
AAGAAGGTTTGGTTTATTTTGACGATGATAAAGCCTGTTATGTTTCTAGAAAATATATCAAAGACTTAAGGTCAAAAATG
GAAAATCTGAAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(19-120)

LytTr DNA-binding domain (LytTR)

(151-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A091BRI3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE2 Streptococcus equinus JB1

100

100

1
  comE/comE1 Streptococcus equinus JB1

45.041

99.18

0.447
  comE/blpR Streptococcus mutans UA159

40.664

98.77

0.402
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

36.255

100

0.373
  comE/comE2 Streptococcus gordonii strain NCTC7865

36.255

100

0.373
  comE Streptococcus pneumoniae R6

35.039

100

0.365
  comE Streptococcus pneumoniae TIGR4

35.039

100

0.365
  comE Streptococcus mitis SK321

35.039

100

0.365
  comE Streptococcus mitis NCTC 12261

35.039

100

0.365
  comE Streptococcus pneumoniae Rx1

35.039

100

0.365
  comE Streptococcus pneumoniae D39

35.039

100

0.365