Detailed information NTG0811079

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: RS171_RS20670
• Genome accession: NZ_CP135649
• Coordinates: 4123407..4126256 (-)
• Length: 949 a.a.
• NCBI ID: WP_109963298.1
• Uniprot ID: -
• Organism: Escherichia coli strain TUM14664
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4118407..4131256

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RS171_RS20645 (RS171_20645)	yfdX2	4118863..4119750 (-)	888	WP_032177823.1	heat resistance protein YfdX2	-
RS171_RS20650 (RS171_20650)	yfdX1	4119853..4120767 (-)	915	WP_096179976.1	heat resistance protein YfdX1	-
RS171_RS20655 (RS171_20655)	hsp20-GI	4120790..4121248 (-)	459	WP_001275372.1	small heat shock protein sHSP20-GI	-
RS171_RS20660 (RS171_20660)	ftsH	4121336..4123155 (-)	1820	Protein_4033	ATP-dependent zinc metalloprotease FtsH	-
RS171_RS20665 (RS171_20665)	-	4123216..4123407 (-)	192	WP_001446316.1	hypothetical protein	-
RS171_RS20670 (RS171_20670)	clpC	4123407..4126256 (-)	2850	WP_109963298.1	heat shock survival AAA family ATPase ClpK	Regulator
RS171_RS20675 (RS171_20675)	hsp20	4126362..4126931 (-)	570	WP_007780320.1	small heat shock protein sHSP20	-
RS171_RS20680 (RS171_20680)	-	4126950..4127087 (+)	138	WP_074577435.1	ABC transporter substrate-binding protein	-
RS171_RS20685 (RS171_20685)	-	4127071..4127247 (-)	177	WP_080601204.1	helix-turn-helix domain-containing protein	-
RS171_RS20690 (RS171_20690)	-	4127476..4127739 (-)	264	Protein_4039	hypothetical protein	-
RS171_RS20695 (RS171_20695)	-	4127754..4128017 (+)	264	WP_071601456.1	transposase	-
RS171_RS20700 (RS171_20700)	-	4127962..4128126 (+)	165	Protein_4041	transposase domain-containing protein	-
RS171_RS20705 (RS171_20705)	-	4128344..4129552 (+)	1209	WP_074576645.1	IS256 family transposase	-
RS171_RS20710 (RS171_20710)	-	4129649..4129876 (+)	228	Protein_4043	hypothetical protein	-
RS171_RS20715 (RS171_20715)	-	4129916..4130557 (-)	642	WP_244570173.1	EAL domain-containing protein	-

Sequence

Protein

• Length: 949 a.a.
• Molecular weight: 104390.10 Da
• Isoelectric Point: 5.7824

>NTDB_id=811079 RS171_RS20670 WP_109963298.1 4123407..4126256(-) (clpC) [Escherichia coli strain TUM14664]
MARKQCQVCGQPATVRVEANLNGRHSTMLLCDDHYRQLVRQQKRTVSPLEALFGSRSGLFEDFLGSDFFRIGDDTTPVAA
DTDDVVDASFGEPAAAGSGAPRRRGSGLASRISEQSEALLQEAAKHAAEFGRSEVDTEHLLLALADSDVVKTTLGQFKIK
VDDLKRQIESEAKRGDKPFEGEIGVSPRVKDALSRAFVASNELGHSYVGPEHFLIGLAEEGEGLAANLLRRYGLTPQALR
QQVSKVVGKGAEDGRAETPTNTPELDKYSRDLTKMARDGKLDPVIGRAQEIETTIEVLARRKKNNPVLIGEPGVGKTAIV
EGLAQRMVAGEVPETLRDKRLVELNINAMVAGAKYRGEFEERVQKVLKEVTEHQGELILFIDEVHTIVGAGQGGGEGGLD
VANVFKPMMARGELNLIGATTLNEYQKYIEKDAALERRFQPVTVPEPTVAQTIMILRGLRDTFEAHHKVSISEDAIIAAA
ELSDRYITARFLPDKAIDLLDQAAARVKLSATARPVAVQELESELYQLRREQDYVAARKQYDQAAELGKRIEAKEAELKK
LVEDWERERASGSAEVKAEHVAQIVSRLTGIPVNELTVEEREKLLHLEQRLHERLVGQDEAVRAVADAVRLSRAGLREGS
KPVATFLFLGPTGVGKTELAKALAESIYGDEHALLRIDMSEYGERHTVARLVGAPPGYVGYDEGGQLTEKVRRKPYSVLL
LDEIEKAHPDVYNILLQVFDDGRLTDGKGRVVDFTNTIIIATSNLGSDIIQRRLKARGAAGEEYEKTKAEVMDVLRGHFR
PEFLNRIDEIIVFHALGKEEIRHIVGLQLDRVARSAASQGVTLTFDQTLIDHFAEEGYKPEFGARELKRLIRSDLETALA
REMLGGSIGKGDHASARWDDKAERVVFEPKEPPHTPAEPEQPDVAKATETPHGDAGKGSRKKKSASDAS

Nucleotide

• Length: 2850 bp

>NTDB_id=811079 RS171_RS20670 WP_109963298.1 4123407..4126256(-) (clpC) [Escherichia coli strain TUM14664]
ATGGCCAGAAAACAATGCCAGGTCTGCGGCCAACCCGCCACCGTGCGGGTGGAAGCCAATCTCAACGGTCGTCACAGCAC
CATGCTGTTGTGCGACGATCATTACCGGCAATTAGTGCGCCAGCAAAAGCGCACCGTTTCGCCGCTGGAAGCCTTGTTCG
GTTCGCGCAGCGGCCTGTTCGAGGACTTCCTCGGCAGTGACTTCTTCCGCATCGGCGACGACACGACGCCCGTTGCCGCC
GATACCGATGACGTGGTCGATGCCTCGTTTGGCGAGCCCGCCGCCGCAGGTTCGGGTGCGCCGCGCCGTCGCGGCAGTGG
GCTGGCCAGCCGCATCAGCGAACAGTCGGAAGCCTTGTTGCAGGAGGCCGCCAAACACGCTGCCGAATTTGGCCGCTCCG
AGGTGGATACCGAACATCTGCTGCTGGCGCTGGCCGACAGCGACGTGGTCAAGACCACCCTGGGTCAGTTCAAGATCAAG
GTCGATGACCTCAAGCGGCAGATCGAGTCTGAGGCCAAGCGCGGGGACAAGCCCTTCGAGGGCGAGATCGGCGTGTCGCC
GCGCGTGAAGGATGCGCTCAGCCGCGCCTTCGTGGCCTCCAATGAACTCGGCCATTCTTATGTCGGTCCAGAGCATTTCC
TGATCGGTCTGGCCGAGGAAGGCGAAGGGCTGGCCGCCAACCTGCTGCGCCGCTACGGCCTGACGCCGCAGGCGCTGCGC
CAACAGGTCAGCAAGGTGGTCGGCAAGGGCGCCGAGGATGGCCGCGCTGAGACCCCGACCAACACGCCAGAACTCGACAA
GTACTCGCGCGACCTGACCAAGATGGCGCGCGACGGCAAGCTCGACCCGGTGATCGGCCGCGCGCAGGAGATCGAAACCA
CCATCGAGGTGCTGGCCCGGCGCAAGAAGAACAACCCGGTGCTGATCGGCGAGCCGGGTGTGGGCAAGACCGCCATCGTC
GAAGGGCTGGCGCAGCGCATGGTGGCAGGTGAAGTGCCCGAGACCTTGCGCGACAAGCGCCTGGTGGAACTCAACATCAA
CGCCATGGTGGCCGGCGCCAAATATCGCGGCGAGTTCGAGGAGCGCGTGCAGAAGGTGCTGAAGGAGGTGACCGAGCACC
AGGGCGAGCTGATTTTGTTCATCGACGAGGTGCACACCATCGTCGGTGCCGGCCAGGGCGGTGGCGAAGGCGGGCTGGAC
GTGGCCAACGTGTTCAAACCGATGATGGCGCGCGGTGAACTCAACCTGATCGGCGCCACGACGCTGAACGAGTACCAGAA
ATACATCGAGAAGGATGCCGCACTGGAGCGGCGCTTCCAGCCGGTGACGGTGCCCGAGCCGACGGTGGCCCAGACCATCA
TGATTCTGCGCGGCCTGCGCGACACCTTCGAGGCGCACCACAAGGTCAGCATCTCCGAGGACGCGATCATCGCGGCGGCC
GAGTTGTCCGACCGCTACATCACGGCGCGCTTCCTGCCGGACAAGGCGATCGACCTGCTCGACCAGGCGGCCGCGCGCGT
GAAGCTGTCGGCCACGGCCCGGCCGGTGGCCGTGCAGGAGCTGGAGTCCGAACTGTACCAGCTGCGGCGTGAACAGGATT
ACGTGGCCGCGCGCAAGCAGTACGACCAGGCCGCCGAGCTCGGCAAGCGCATCGAAGCCAAGGAGGCCGAGCTCAAGAAG
CTCGTCGAGGACTGGGAGCGGGAGCGGGCCTCCGGCAGTGCCGAGGTCAAGGCGGAACACGTGGCGCAGATCGTCTCGCG
CCTGACCGGCATCCCGGTCAACGAGTTGACGGTGGAAGAGCGCGAAAAGCTGCTGCACTTGGAACAACGGCTGCACGAGC
GCCTGGTGGGACAAGACGAAGCGGTCCGTGCCGTGGCCGATGCCGTGCGGCTGTCCCGCGCCGGCCTGCGCGAAGGCAGC
AAACCGGTGGCTACCTTCCTGTTTCTGGGCCCGACCGGGGTGGGCAAGACCGAGCTCGCCAAGGCATTGGCCGAATCGAT
CTACGGCGATGAGCACGCCCTGTTGCGCATCGACATGTCGGAATATGGCGAACGCCATACCGTGGCGCGGCTGGTGGGCG
CGCCTCCGGGCTATGTCGGTTACGACGAAGGCGGTCAGCTCACCGAGAAGGTGCGGCGCAAGCCCTACAGCGTGCTGCTG
CTCGACGAGATCGAGAAGGCACACCCTGACGTCTACAACATCCTGCTGCAAGTGTTCGACGACGGTCGCCTCACCGACGG
CAAGGGCCGGGTGGTGGATTTCACCAACACCATCATCATCGCCACGTCCAACCTGGGTTCGGACATCATCCAGCGACGGC
TGAAGGCGCGTGGGGCGGCCGGCGAGGAGTACGAAAAGACCAAGGCCGAGGTCATGGACGTGCTGCGCGGCCACTTCCGG
CCCGAGTTCCTCAACCGCATCGACGAGATCATCGTCTTCCATGCGCTGGGCAAGGAGGAGATCCGCCACATCGTCGGCCT
GCAGCTCGATCGCGTGGCGCGCAGCGCCGCCAGCCAGGGCGTGACGCTCACTTTCGATCAGACGCTCATCGACCATTTCG
CGGAAGAAGGCTACAAGCCCGAGTTCGGTGCGCGTGAACTCAAGCGCCTGATCCGCAGCGATCTGGAAACTGCGCTGGCG
CGCGAGATGCTCGGTGGCAGCATCGGCAAGGGCGATCACGCCAGCGCACGCTGGGACGACAAGGCCGAACGCGTGGTGTT
CGAACCCAAAGAGCCACCGCATACCCCGGCCGAGCCGGAGCAGCCGGATGTCGCGAAGGCGACCGAGACGCCGCACGGCG
ACGCTGGCAAAGGCTCGCGCAAGAAGAAGTCGGCGAGCGACGCATCTTGA

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (123-171)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (199-248)

• ATPase family associated with various cellular activities (AAA) (AAA) (307-428)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (816-894)

• AAA lid domain (AAA_lid_9) (449-547)

• AAA domain (Cdc48 subfamily) (AAA_2) (641-810)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	50.818	83.772	0.426
clpC	Streptococcus thermophilus LMD-9	42.702	87.355	0.373
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.419	85.669	0.372
clpC	Streptococcus thermophilus LMG 18311	42.615	87.039	0.371
clpC	Streptococcus mutans UA159	42.432	84.932	0.36
clpC	Streptococcus pneumoniae Rx1	41.963	85.88	0.36
clpC	Streptococcus pneumoniae D39	41.963	85.88	0.36