Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   PO908_RS01250 Genome accession   NZ_CP117042
Coordinates   225446..226387 (+) Length   313 a.a.
NCBI ID   WP_394468008.1    Uniprot ID   -
Organism   Streptococcus anginosus strain CGMH_KH1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 220446..231387
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PO908_RS01225 (PO908_01225) - 220757..221956 (+) 1200 WP_021001230.1 phosphoglycerate kinase -
  PO908_RS01230 (PO908_01230) - 222471..223001 (+) 531 WP_003032280.1 aromatic acid exporter family protein -
  PO908_RS01235 (PO908_01235) - 223078..223437 (+) 360 WP_003028467.1 MerR family transcriptional regulator -
  PO908_RS01240 (PO908_01240) glnA 223476..224822 (+) 1347 WP_003027006.1 type I glutamate--ammonia ligase -
  PO908_RS01245 (PO908_01245) - 225011..225376 (+) 366 WP_003027003.1 DUF1033 family protein -
  PO908_RS01250 (PO908_01250) comYA 225446..226387 (+) 942 WP_394468008.1 competence type IV pilus ATPase ComGA Machinery gene
  PO908_RS01255 (PO908_01255) comYB 226329..227351 (+) 1023 WP_041783985.1 competence type IV pilus assembly protein ComGB Machinery gene
  PO908_RS01260 (PO908_01260) comYC 227348..227665 (+) 318 WP_003028473.1 competence type IV pilus major pilin ComGC Machinery gene
  PO908_RS01265 (PO908_01265) comYD 227625..228053 (+) 429 WP_021001232.1 competence type IV pilus minor pilin ComGD Machinery gene
  PO908_RS01270 (PO908_01270) comGE/cglE 228025..228318 (+) 294 WP_021001233.1 competence type IV pilus minor pilin ComGE Machinery gene
  PO908_RS01275 (PO908_01275) comGF/cglF 228302..228739 (+) 438 WP_041783987.1 competence type IV pilus minor pilin ComGF Machinery gene
  PO908_RS01280 (PO908_01280) comGG 228720..229046 (+) 327 WP_021001234.1 competence type IV pilus minor pilin ComGG -
  PO908_RS01285 (PO908_01285) comYH 229118..230071 (+) 954 WP_021001235.1 class I SAM-dependent methyltransferase Machinery gene
  PO908_RS01290 (PO908_01290) - 230118..231317 (+) 1200 WP_021001236.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35937.21 Da        Isoelectric Point: 6.3128

>NTDB_id=782215 PO908_RS01250 WP_394468008.1 225446..226387(+) (comYA) [Streptococcus anginosus strain CGMH_KH1]
MVQNIAQAIICQAKKEQAQDIYFVPRENMYELYMRIGDERRFIQQYAFEEMAAVISHFKFTAGMNVGEKRRSQLGSCDYQ
YGDKKMSLRLSTVGDYRGYESLVIRLLHDEEAELKFWFAQIPELKERFKQRGLYLFSGPVGSGKTTLMHQLAQERFADQQ
IMSIEDPVEIKQAGMLQLQLNEAIGLTYESLIKLSLRHRPDLLIIGEIRDAETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVTEAELKIVLQGICYQRLIAKGGIVDFVSERYQEHEPSDWNKQIDQLYAAGHVTFEQAETEKIIHS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=782215 PO908_RS01250 WP_394468008.1 225446..226387(+) (comYA) [Streptococcus anginosus strain CGMH_KH1]
ATGGTTCAAAACATTGCACAGGCTATTATTTGCCAAGCTAAAAAAGAGCAGGCTCAGGACATTTATTTTGTTCCAAGGGA
AAATATGTATGAGCTATACATGCGAATTGGAGATGAACGGCGCTTTATCCAACAGTATGCATTTGAAGAGATGGCAGCAG
TAATTAGTCATTTTAAGTTTACCGCTGGGATGAATGTCGGCGAAAAACGTAGAAGCCAGTTAGGATCTTGTGATTATCAA
TATGGTGATAAGAAAATGTCATTACGACTGTCAACAGTAGGGGATTATCGTGGATACGAAAGTCTGGTGATTCGTTTATT
GCATGATGAAGAGGCAGAGTTGAAGTTTTGGTTTGCTCAAATCCCAGAGTTAAAAGAACGCTTCAAACAACGAGGGCTTT
ATCTTTTTTCGGGACCGGTAGGAAGTGGTAAAACTACTCTCATGCACCAGTTGGCTCAAGAGCGTTTTGCCGATCAGCAA
ATCATGTCAATTGAAGATCCGGTTGAAATCAAACAAGCAGGGATGTTACAGCTGCAGCTGAACGAAGCGATTGGTTTAAC
TTATGAAAGTTTGATTAAACTTTCTCTTCGGCATCGACCAGATTTATTGATTATCGGAGAGATTCGTGATGCGGAGACAG
CAAGGGCAGTTGTTCGAGCTAGCTTAACGGGAGTGACTGTTTTTTCAACTATTCATGCTAAAAGCGTACGAGGTGTCTAT
GAACGGTTGCTGGAGTTGGGAGTGACAGAAGCAGAGCTGAAAATTGTTTTGCAAGGAATTTGCTACCAACGGTTAATTGC
GAAAGGAGGAATAGTGGATTTTGTCAGTGAAAGGTATCAAGAGCATGAGCCAAGTGACTGGAATAAGCAGATTGATCAGC
TTTATGCAGCAGGACATGTCACTTTTGAGCAGGCAGAAACGGAAAAAATTATCCATAGTTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

81.935

99.042

0.811
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae D39

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae R6

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

75.399

100

0.754
  comYA Streptococcus mutans UA159

64.309

99.361

0.639
  comYA Streptococcus mutans UA140

64.309

99.361

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.935

99.042

0.613
  comGA Lactococcus lactis subsp. cremoris KW2

54.341

99.361

0.54
  comGA Latilactobacillus sakei subsp. sakei 23K

42.349

89.776

0.38