Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   O6R09_RS00680 Genome accession   NZ_CP114883
Coordinates   101235..102176 (+) Length   313 a.a.
NCBI ID   WP_269725665.1    Uniprot ID   -
Organism   Streptococcus alactolyticus strain LGM     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 96235..107176
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O6R09_RS00670 (O6R09_00670) rpoC 97037..100678 (+) 3642 WP_167829244.1 DNA-directed RNA polymerase subunit beta' -
  O6R09_RS00675 (O6R09_00675) - 100795..101103 (+) 309 WP_154454148.1 DUF1033 family protein -
  O6R09_RS00680 (O6R09_00680) comGA/cglA 101235..102176 (+) 942 WP_269725665.1 competence type IV pilus ATPase ComGA Machinery gene
  O6R09_RS00685 (O6R09_00685) comYB 102058..103143 (+) 1086 WP_374041727.1 competence type IV pilus assembly protein ComGB Machinery gene
  O6R09_RS00690 (O6R09_00690) comYC 103143..103436 (+) 294 WP_235280789.1 competence type IV pilus major pilin ComGC Machinery gene
  O6R09_RS00695 (O6R09_00695) comGD 103399..103851 (+) 453 WP_154454146.1 competence type IV pilus minor pilin ComGD -
  O6R09_RS00700 (O6R09_00700) comGE 103874..104098 (+) 225 WP_154454160.1 competence type IV pilus minor pilin ComGE -
  O6R09_RS00705 (O6R09_00705) comYF 104058..104519 (+) 462 WP_269725666.1 competence type IV pilus minor pilin ComGF Machinery gene
  O6R09_RS00710 (O6R09_00710) comGG 104491..104817 (+) 327 WP_154454144.1 competence type IV pilus minor pilin ComGG -
  O6R09_RS00715 (O6R09_00715) comYH 104892..105848 (+) 957 WP_154454143.1 class I SAM-dependent methyltransferase Machinery gene
  O6R09_RS00720 (O6R09_00720) - 105900..107114 (+) 1215 WP_154454142.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35312.32 Da        Isoelectric Point: 5.8758

>NTDB_id=767306 O6R09_RS00680 WP_269725665.1 101235..102176(+) (comGA/cglA) [Streptococcus alactolyticus strain LGM]
MIQDLAKAIIANAVAKAAQDIYILPRQNRYEVYYRLGNDKELIDCFDADKMTNLISHFKFVAGMDVGEKRRSQLGSCDYT
FAEDEQISLRLSSVGDYRGRESLVIRLLYYGQKSLHYWFDGLEEALSVVNGRGLYLFSGPVGSGKTTLMYQLVQEKFPDK
QVITIEDPVEIQQDNMLQLQLNDEIGMTYDELIKLSLRHRPDILIIGEIRDSDTAHAVIRASLTGAVVFSTIHAKSISGV
YARLLELGISQQELENSLHAVVYQRLIGGGGVIDVAKDRFKEHQPSNWNQKMDQLVAQGHLSKERAAIEKITL

Nucleotide


Download         Length: 942 bp        

>NTDB_id=767306 O6R09_RS00680 WP_269725665.1 101235..102176(+) (comGA/cglA) [Streptococcus alactolyticus strain LGM]
ATGATTCAAGATTTAGCAAAAGCTATCATAGCAAATGCGGTCGCTAAAGCTGCTCAAGATATTTATATCCTACCTAGGCA
AAACCGCTATGAAGTCTATTATCGGCTAGGTAATGACAAGGAATTGATAGATTGCTTTGATGCTGACAAAATGACTAACC
TGATTAGCCATTTTAAATTTGTCGCAGGCATGGACGTTGGGGAAAAGCGTCGTAGCCAACTAGGTTCGTGCGACTACACC
TTTGCAGAAGATGAGCAAATCTCGCTACGTTTATCAAGTGTCGGGGACTACCGCGGTCGAGAGAGTTTGGTAATTCGTTT
GCTTTATTATGGTCAAAAATCTCTCCATTATTGGTTTGATGGGCTAGAGGAAGCTTTATCTGTTGTCAATGGTAGGGGAC
TTTATCTCTTTTCAGGTCCAGTTGGTAGTGGAAAAACTACGCTGATGTATCAGTTGGTTCAGGAAAAATTTCCAGATAAA
CAAGTCATTACCATCGAAGATCCTGTGGAAATTCAGCAGGATAATATGTTGCAGCTGCAATTAAACGATGAAATAGGCAT
GACTTACGATGAGCTGATCAAATTGTCCTTGCGGCATCGACCAGATATTCTCATTATCGGAGAAATTCGTGATAGCGATA
CGGCACACGCGGTTATTAGGGCCAGTTTAACAGGAGCTGTGGTATTTTCGACCATTCATGCTAAAAGCATTTCAGGTGTT
TATGCGCGTTTATTGGAATTAGGTATCAGTCAGCAAGAGTTGGAGAATAGTCTGCACGCAGTGGTTTACCAACGGTTAAT
TGGGGGAGGAGGTGTGATAGATGTTGCAAAAGATAGATTTAAAGAGCACCAGCCAAGCAACTGGAATCAAAAAATGGACC
AGTTGGTTGCACAAGGACATCTTTCCAAAGAACGAGCGGCCATTGAAAAAATTACCCTTTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

66.452

99.042

0.658
  comYA Streptococcus mutans UA159

66.238

99.361

0.658
  comYA Streptococcus mutans UA140

66.238

99.361

0.658
  comYA Streptococcus gordonii str. Challis substr. CH1

62.701

99.361

0.623
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

61.538

99.681

0.613
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.022

100

0.61
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.022

100

0.61
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.022

100

0.61
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.022

100

0.61
  comGA Lactococcus lactis subsp. cremoris KW2

53.035

100

0.53
  comGA Latilactobacillus sakei subsp. sakei 23K

42.537

85.623

0.364