Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   O6R09_RS00685 Genome accession   NZ_CP114883
Coordinates   102058..103143 (+) Length   361 a.a.
NCBI ID   WP_374041727.1    Uniprot ID   -
Organism   Streptococcus alactolyticus strain LGM     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 97058..108143
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O6R09_RS00675 (O6R09_00675) - 100795..101103 (+) 309 WP_154454148.1 DUF1033 family protein -
  O6R09_RS00680 (O6R09_00680) comGA/cglA 101235..102176 (+) 942 WP_269725665.1 competence type IV pilus ATPase ComGA Machinery gene
  O6R09_RS00685 (O6R09_00685) comYB 102058..103143 (+) 1086 WP_374041727.1 competence type IV pilus assembly protein ComGB Machinery gene
  O6R09_RS00690 (O6R09_00690) comYC 103143..103436 (+) 294 WP_235280789.1 competence type IV pilus major pilin ComGC Machinery gene
  O6R09_RS00695 (O6R09_00695) comGD 103399..103851 (+) 453 WP_154454146.1 competence type IV pilus minor pilin ComGD -
  O6R09_RS00700 (O6R09_00700) comGE 103874..104098 (+) 225 WP_154454160.1 competence type IV pilus minor pilin ComGE -
  O6R09_RS00705 (O6R09_00705) comYF 104058..104519 (+) 462 WP_269725666.1 competence type IV pilus minor pilin ComGF Machinery gene
  O6R09_RS00710 (O6R09_00710) comGG 104491..104817 (+) 327 WP_154454144.1 competence type IV pilus minor pilin ComGG -
  O6R09_RS00715 (O6R09_00715) comYH 104892..105848 (+) 957 WP_154454143.1 class I SAM-dependent methyltransferase Machinery gene
  O6R09_RS00720 (O6R09_00720) - 105900..107114 (+) 1215 WP_154454142.1 acetate kinase -
  O6R09_RS00725 (O6R09_00725) - 107235..107873 (+) 639 WP_154454141.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 361 a.a.        Molecular weight: 41421.03 Da        Isoelectric Point: 9.7032

>NTDB_id=767307 O6R09_RS00685 WP_374041727.1 102058..103143(+) (comYB) [Streptococcus alactolyticus strain LGM]
MQKIDLKSTSQATGIKKWTSWLHKDIFPKNERPLKKLPFSKQRKLIQLFNNLFHSGFHLSEILSFLRRSQLLEADYIDVM
QNSLLAGGNLSLMMSQLGFSDTIVTQMALADIHGNSQRSLVKIDAYLTSMGAVRKKLLEVMTYPVMLLGFLVLIMVGLNH
YLLPQLEGSNLATQLIQHFPLLFLVGTVMITLVVLALYLYQKRLPRIRVYSQLSRLPFIGNTIRLYLTAYYAREWGNLIG
QGVELIDIVAIMQQQKSRLFQEIGQDMQEALLSGQAFHQKVLDYPFFLTELGLMIEYGEIKSKLGSELDIYAEETWQRFF
GKMNQATQLIQPLVFIFVALVIVLIYVAMLLPMYQNMGGYF

Nucleotide


Download         Length: 1086 bp        

>NTDB_id=767307 O6R09_RS00685 WP_374041727.1 102058..103143(+) (comYB) [Streptococcus alactolyticus strain LGM]
TTGCAAAAGATAGATTTAAAGAGCACCAGCCAAGCAACTGGAATCAAAAAATGGACCAGTTGGTTGCACAAGGACATCTT
TCCAAAGAACGAGCGGCCATTGAAAAAATTACCCTTTAGCAAACAACGAAAACTCATTCAGTTATTTAATAATTTGTTTC
ATAGTGGATTTCATTTGTCGGAAATTCTGTCCTTTCTAAGACGTAGTCAGCTGCTGGAGGCTGATTATATCGATGTGATG
CAAAATAGCTTATTGGCTGGAGGTAATCTATCGCTCATGATGTCCCAGCTAGGTTTCTCTGATACGATTGTAACGCAGAT
GGCTTTGGCGGATATTCACGGCAATAGTCAAAGGAGCCTTGTAAAAATTGATGCCTATCTAACTAGCATGGGTGCCGTAA
GAAAGAAATTGCTCGAGGTTATGACCTACCCTGTCATGTTACTTGGCTTCCTTGTGTTGATTATGGTGGGGCTAAATCAT
TATTTATTGCCACAACTGGAAGGTAGCAATCTAGCCACTCAGTTGATTCAGCATTTTCCCCTGCTGTTTTTAGTGGGAAC
TGTGATGATTACGCTCGTGGTTCTTGCGCTTTATCTTTACCAAAAACGCTTGCCTCGCATTCGGGTGTACAGTCAACTCA
GTCGCCTTCCTTTTATTGGAAATACCATTCGGTTGTATTTGACGGCTTATTACGCACGGGAATGGGGCAATCTCATCGGT
CAAGGTGTTGAGTTGATTGACATTGTGGCGATTATGCAGCAACAAAAATCACGCTTGTTTCAAGAAATTGGGCAAGATAT
GCAAGAAGCTTTACTGTCAGGGCAAGCCTTTCATCAAAAAGTATTGGATTATCCTTTTTTTCTGACAGAACTAGGACTGA
TGATTGAGTACGGTGAAATCAAATCAAAATTAGGCAGTGAATTAGACATTTACGCCGAGGAAACCTGGCAACGTTTCTTT
GGCAAAATGAACCAAGCAACCCAGTTGATTCAACCGCTAGTCTTTATCTTTGTGGCTTTGGTGATTGTCTTGATTTACGT
AGCGATGTTGTTGCCAATGTATCAAAATATGGGAGGGTATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(232-352)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

58.876

93.629

0.551
  comYB Streptococcus mutans UA140

61.981

86.704

0.537
  comYB Streptococcus mutans UA159

61.981

86.704

0.537
  comGB/cglB Streptococcus mitis NCTC 12261

59.077

90.028

0.532
  comGB/cglB Streptococcus mitis SK321

56.347

89.474

0.504
  comGB/cglB Streptococcus pneumoniae Rx1

55.728

89.474

0.499
  comGB/cglB Streptococcus pneumoniae D39

55.728

89.474

0.499
  comGB/cglB Streptococcus pneumoniae R6

55.728

89.474

0.499
  comGB/cglB Streptococcus pneumoniae TIGR4

55.728

89.474

0.499
  comGB Lactococcus lactis subsp. cremoris KW2

50

90.305

0.452