NTDB

Overview

Name	comX/comX2	Type	Regulator
Locus tag	OTU45_RS00340	Genome accession	NZ_CP113114
Coordinates	62964..63443 (+)	Length	159 a.a.
NCBI ID	WP_000588864.1	Uniprot ID	-
Organism	Streptococcus pneumoniae strain NP1
Function	activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 57964..68443

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OTU45_RS00325 (OTU45_00325)	tilS	59045..60322 (+)	1278	WP_001209049.1	tRNA lysidine(34) synthetase TilS	-
OTU45_RS00330 (OTU45_00330)	hpt	60326..60868 (+)	543	WP_000892185.1	hypoxanthine phosphoribosyltransferase	-
OTU45_RS00335 (OTU45_00335)	ftsH	60884..62842 (+)	1959	WP_000744557.1	ATP-dependent zinc metalloprotease FtsH	-
OTU45_RS00340 (OTU45_00340)	comX/comX2	62964..63443 (+)	480	WP_000588864.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

Download Length: 159 a.a. Molecular weight: 19845.46 Da Isoelectric Point: 7.3797

                                >NTDB_id=760313 OTU45_RS00340 WP_000588864.1 62964..63443(+) (comX/comX2) [Streptococcus pneumoniae strain NP1]

MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLADDIPRLRKYFKTKFRNRILDYIRKQESQKRR

YDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH

Nucleotide

Download Length: 480 bp

                                >NTDB_id=760313 OTU45_RS00340 WP_000588864.1 62964..63443(+) (comX/comX2) [Streptococcus pneumoniae strain NP1]

ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT

GTCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGCAGACGATATTCCAC

GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAGA

TACGATAAAGAACCCTATGAAGAAGTGGGAGAGATCAGTCATCGTATAAGTGAGGGAGGTCTCTGGCTAGATGATTATTA

TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA

ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCACTAG

Domains

No domain identified.

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comX/comX2	Streptococcus pneumoniae Rx1	99.371	100	0.994
comX/comX1	Streptococcus pneumoniae Rx1	99.371	100	0.994
comX/comX2	Streptococcus pneumoniae D39	99.371	100	0.994
comX/comX1	Streptococcus pneumoniae D39	99.371	100	0.994
comX/comX2	Streptococcus pneumoniae R6	99.371	100	0.994
comX/comX1	Streptococcus pneumoniae R6	99.371	100	0.994
comX/comX2	Streptococcus pneumoniae TIGR4	98.742	100	0.987
comX/comX1	Streptococcus pneumoniae TIGR4	98.742	100	0.987
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	91.824	100	0.918
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	91.824	100	0.918
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	89.937	100	0.899
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	89.873	99.371	0.893
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	48.718	98.113	0.478
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	48.718	98.113	0.478
comX/sigX	Streptococcus mutans UA159	46	94.34	0.434
comX/sigX	Streptococcus suis isolate S10	45.033	94.969	0.428
comX/sigX	Streptococcus suis D9	45.033	94.969	0.428
comX/sigX	Streptococcus suis P1/7	45.033	94.969	0.428
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	39.216	96.226	0.377
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	39.216	96.226	0.377
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	40	94.34	0.377
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	40	94.34	0.377
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	40	94.34	0.377
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	40	94.34	0.377

Detailed information NTG0760313