Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   EL263_RS10125 Genome accession   NZ_AP018938
Coordinates   1876828..1877769 (-) Length   313 a.a.
NCBI ID   WP_000249549.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain ATCC 49619     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1871828..1882769
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL263_RS10085 (SPAT_1910) comYH 1872314..1873267 (-) 954 WP_050308921.1 class I SAM-dependent methyltransferase Machinery gene
  EL263_RS10090 - 1873328..1873922 (-) 595 Protein_1882 class I SAM-dependent methyltransferase -
  EL263_RS10095 (SPAT_1913) comGG/cglG 1874059..1874472 (-) 414 WP_050102600.1 competence type IV pilus minor pilin ComGG Machinery gene
  EL263_RS10100 (SPAT_1914) comGF/cglF 1874450..1874911 (-) 462 WP_000250544.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL263_RS10105 (SPAT_1915) comGE/cglE 1874874..1875176 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  EL263_RS10110 (SPAT_1916) comGD/cglD 1875139..1875543 (-) 405 WP_000588020.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL263_RS10115 (SPAT_1917) comGC/cglC 1875536..1875862 (-) 327 WP_000738632.1 comG operon protein ComGC Machinery gene
  EL263_RS10120 (SPAT_1918) comGB/cglB 1875864..1876880 (-) 1017 WP_114880773.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL263_RS10125 (SPAT_1919) comGA/cglA/cilD 1876828..1877769 (-) 942 WP_000249549.1 competence type IV pilus ATPase ComGA Machinery gene
  EL263_RS10130 (SPAT_1920) - 1877845..1878210 (-) 366 WP_000286415.1 DUF1033 family protein -
  EL263_RS10135 (SPAT_1921) - 1878361..1879419 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  EL263_RS10140 (SPAT_1922) nagA 1879582..1880733 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  EL263_RS10145 (SPAT_1923) - 1880886..1882703 (-) 1818 WP_001220922.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35543.45 Da        Isoelectric Point: 6.0083

>NTDB_id=71979 EL263_RS10125 WP_000249549.1 1876828..1877769(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain ATCC 49619]
MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKIASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFANRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=71979 EL263_RS10125 WP_000249549.1 1876828..1877769(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain ATCC 49619]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCGGCTCGGAAAAAAGGGGCGCAAGACATTTATTTTGTCCCTAAGTT
AGATGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATAGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACTTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAACAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

99.042

100

0.99
  comGA/cglA/cilD Streptococcus pneumoniae D39

99.042

100

0.99
  comGA/cglA/cilD Streptococcus pneumoniae R6

99.042

100

0.99
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

99.042

100

0.99
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

96.805

100

0.968
  comYA Streptococcus gordonii str. Challis substr. CH1

78.065

99.042

0.773
  comYA Streptococcus mutans UA159

66.238

99.361

0.658
  comYA Streptococcus mutans UA140

66.238

99.361

0.658
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.903

99.042

0.623
  comGA Lactococcus lactis subsp. cremoris KW2

55.128

99.681

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

41.912

86.901

0.364

Multiple sequence alignment